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My personal journey with breast cancer and exploring spatial transcriptomics

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From MGI 29 Oct 2024

Unraveling the mystery of cancer resistance

Every multicellular creature - whether soaring through the skies, swimming in the ocean's depths or roaming the earth's surface - shares a common vulnerability: the uncontrolled growth of cells known as cancer.

29 Oct 2024

A promising new strategy for malaria drug development

Malaria kills over 600,000 people a year, and as the climate warms, the potential range of the disease is growing. While some drugs can effectively prevent and treat malaria, resistance to those drugs is also on the rise.

29 Oct 2024

Space-based research uncovers key to cancer cell survival

In October, we think pink, and for a good reason - one out of every eight women will be diagnosed with breast cancer in their lifetime, and each year, 2 million women are given this frightening diagnosis. Biotechnology startup MicroQuin leveraged the International Space Station (ISS) National Laboratory to grow 3D breast and prostate cancer cell cultures to learn more about how these cancers develop and grow.

29 Oct 2024

Researchers uncover the link between EVs and tissue damage

A landmark study led by WEHI and La Trobe University has found a potential new diagnostic marker that could be used to better detect the level of tissue damage in our bodies.

29 Oct 2024

Study provides new insights into the molecular causes of rare, fatal hereditary disease

A study entitled "IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport", now published in the open access journal "Cellular and Molecular Life Sciences", provides new insights into the molecular causes of a rare and usually fatal hereditary disease called MEDS1.

28 Oct 2024

EBUS-TBNA proves effective for tumor molecular analysis in lung cancer

Tumor molecular analysis using next-generation sequencing (NGS) is the standard of care for guiding lung cancer treatment. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive technique used to sample mediastinal lymph nodes for diagnosing and staging lung cancer.

28 Oct 2024

Researchers uncover key mechanisms of CRISPR gene editing

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy.

28 Oct 2024

New research unveils mechanism behind deadly neuroendocrine prostate cancer

A leading scientist whose discoveries about prostate cancer led to lifesaving treatments is now shedding light on an emerging and deadlier form of the disease: neuroendocrine prostate cancer (NEPC).

28 Oct 2024

C. elegans model system accelerates discovery of amyloid inhibitors

An international team led by researchers at the University of Toronto has developed an efficient and robust system, using the C. elegans nematode, to screen for compounds that can stop the growth of amyloid proteins.

28 Oct 2024

Genomic technology used to improve understanding of Marjolin's ulcer

Researchers utilized specialized genomic technology at the University of Calgary to enhance our understanding of Marjolin's ulcer (MU), a rare, highly aggressive skin cancer that affects chronic wounds that can often arise from established scars like those caused by severe burns.

28 Oct 2024

New genetic insights reveal kidney disease risk in West Africans

A study from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people from Ghana and Nigeria.

28 Oct 2024

Novel class of encrypted peptides offers hope against drug-resistant bacteria

In a significant advance against the growing threat of antibiotic-resistant bacteria, researchers have identified a novel class of antimicrobial agents known as encrypted peptides, which may expand the immune system's arsenal of tools to fight infection.

28 Oct 2024

Global leaders gather at the NFCR Summit to drive breakthroughs in cancer care

The 2024 National Foundation for Cancer Research (NFCR) Global Summit and Award Ceremonies for Cancer Research & Entrepreneurship, co-hosted with the AIM-HI Accelerator Fund, convened the world's top experts across cancer research, biotech entrepreneurship, pharmaceuticals, investment, and patient advocacy.

28 Oct 2024

Elucidating the mechanisms behind kidney development

To Alex Hughes, Assistant Professor in Bioengineering within Penn Engineering and in Cell and Developmental Biology within Penn Medicine, the kidney is a work of art. "I find the development of the kidney to be a really beautiful process," says Hughes.

28 Oct 2024

Evosep expanding capabilities with new headquarters to support rising needs in pharma and biotech for proteomics

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From Evosep 28 Oct 2024

Black Americans still suffer worse health. Here’s why there’s so little progress

One morning in late April, a small brick health clinic along the Thurgood Marshall Highway bustled with patients.

28 Oct 2024

New model sheds light on the genetic roots of polygenic diseases

Many statistical models and algorithms used by scientists can be imagined as a "black box." These models are powerful tools that give accurate predictions, but their internal workings are not easily interpretable or understood.

28 Oct 2024

Unlocking the secrets of Usher syndrome

The mistakes are small but carry severe consequences: In Usher syndrome, genetic mutations cause both hearing and vision loss. Cell biologist Professor Uwe Wolfrum from Mainz University is researching the molecular background of this rare genetic disorder - supported by foundations and, not least, by affected individuals themselves

28 Oct 2024

Study aims to construct a circRNA-miRNA-mRNA network in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most fatal malignancies. Epigenetic mechanisms have revealed that noncoding RNAs, such as microRNAs (miRNAs) and circular RNAs (circRNAs), are involved in HCC progression.

27 Oct 2024