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Novel solution could produce accurate, automated placental diagnostic reports

Placentas can provide critical information about the health of the mother and baby, but only 20 percent of placentas are assessed by pathology exams after delivery in the U.S. The cost, time and expertise required to analyze them are prohibitive.

25 Nov 2019

Discovery enables strategies to be developed for preventing malaria transmission

The bacteria that form the gut microbiota influence important processes of the human body, such as digestion, nutrient absorption, and defense against pathogens. The same type of relationship is present in most animals, including in the Anhopheles darlingi mosquito, the main vector of malaria in Brazil.

22 Nov 2019

Combination therapy improves survival in patients with hepatocellular carcinoma

Combination therapy with the PD-L1 inhibitor atezolizumab and the VEGF inhibitor bevacizumab significantly improves overall survival and progression-free survival in patients with unresectable hepatocellular carcinoma compared to standard of care, showed results from a phase 3 study reported at the ESMO Asia 2019 Congress.

22 Nov 2019

Researchers study the effects of hyperoxia on the lung development of germ-free newborn mice

Charitharth Vivek Lal, M.D., and University of Alabama at Birmingham colleagues have used a novel and first-of-its-kind newborn mouse model to study the effect of high oxygen concentrations, or hyperoxia, on lung development of newborn mice that are germ-free -- meaning no microbes colonizing their lungs.

21 Nov 2019

New research project could help reduce unnecessary C-sections in Ireland

A new research project at Trinity College Dublin could have far-reaching implications for the management of labour, making monitoring less intrusive and potentially reducing the number of unnecessary caesarean sections in Ireland.

21 Nov 2019

UTSA research aims to use sulfur to expedite new drug development

Organosulfur compounds are widely present in our bodies and the natural environment. They are found in onions, shallots and even cauliflower. Medical research finds that when consumed, they can protect against cancer, heart disease and even diabetes. There is also evidence of these compounds' antiviral and antibacterial uses. About a quarter of all pharmaceutical drugs currently use OSCs.

21 Nov 2019

Doctors place patients in suspended animation in first trial of its kind

For the first time, doctors have placed people in suspended animation in an effort to repair fatal

21 Nov 2019

Leg cramps could be a sign of peripheral artery disease

Peripheral artery disease develops silently, narrowing blood vessels for decades until the supply of nutrients and oxygen falls low enough to cause cramps and leg pain.

21 Nov 2019

'Fuzzy logic' alarm system may help NICU nurses predict catheter infusion failure

A "fuzzy logic" alarm system may help nurses in the neonatal intensive care unit (NICU) predict impending catheter infusion failure – and prevent complications in critically ill newborns, reports a study in the October issue of Advances in Neonatal Care, official journal of the National Association of Neonatal Nurses.

20 Nov 2019

Carbon monoxide has a beneficial side at low concentrations

Most people think of carbon monoxide as harmful, and with good reason -- the colorless, odorless gas sends 50,000 people in the U.S. to hospitals each year when their furnaces malfunction or car engines run in poorly ventilated spaces. But at low concentrations, carbon monoxide has a beneficial side that scientists are trying to harness to treat diseases, according to an article in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society.

20 Nov 2019

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

20 Nov 2019

Miniscule robots like "Magic School Bus" could clear blood clots

Pulmonary embolism is a condition where a clot forms and blocks the arteries of the lungs and this restricts the blood flow to the lungs and lowers the amount of oxygen reaching the different organs. Statistics from the National Institutes of Health show that pulmonary embolism leads to nearly 200,000 to 300,000 deaths in the United States annually putting it at number three in cardiovascular diseases right after heart attack and stroke.

19 Nov 2019

Directional control of protocell's movement could lead to precision drug delivery

Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the body.

18 Nov 2019

Vaping wrecks immune cell function, increases infection risk

A new study published in the Journal of the American College of Cardiology shows that e-cigarettes have toxic effects on neutrophils function, making them a threat to human health by increasing the likelihood of infection with Gram-negative bacteria.

17 Nov 2019

Clinical trial: Oral drug improves exercise capacity in teens with congenital heart defects

The largest-ever clinical trial of a medication for pediatric cardiology patients found that an oral drug significantly improved exercise capacity in adolescent patients with severe, congenital single-ventricle heart defects.

17 Nov 2019

Modern resuscitation science: Illuminating the complex processes of death

On Monday, November 18, 2019 the New York Academy of Sciences and the Critical Care and Resuscitation Research Program at NYU Langone will present a two part event titled What Happens When We Die? at the Academy's offices in downtown Manhattan.

15 Nov 2019

Researchers decode molecular structure of cytochrome bd oxidase from E. coli

Both humans and many other creatures need oxygen for survival. In the conversion of nutrients into energy, the oxygen is converted to water, for which the enzyme oxidase is responsible. It represents the last step of the so-called respiratory chain.

14 Nov 2019

WPI researchers developing miniaturized device to measure baby's blood oxygen levels

Researchers at Worcester Polytechnic Institute are developing a sensor the size of a Band-Aid that will measure a baby's blood oxygen levels, a vital indication of the lungs' effectiveness and whether the baby's tissue is receiving adequate oxygen supply.

14 Nov 2019

Machine learning algorithm predicts life expectancy in heart failure patients

When Avi Yagil, PhD, Distinguished Professor of Physics at University of California San Diego flew home from Europe in 2012, he thought he had caught a cold from his travels. When a "collection of pills" did not improve his symptoms, his wife encouraged him to see a doctor.

13 Nov 2019

UAB study suggests potential treatment target for IPF

Long-held dogma says lung fibrosis in diseases like idiopathic pulmonary fibrosis, or IPF, results from recurrent injury to alveolar epithelium that is followed by dysregulated repair.

12 Nov 2019