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ASTRO releases updated guidelines for treating locally advanced rectal cancer

The American Society for Radiation Oncology (ASTRO) issued today an updated clinical guideline for physicians who use radiation therapy to treat patients with locally advanced rectal cancer.

25 Nov 2024

History of endometriosis and fibroids linked to higher long-term risk of early death

Researchers examine the impact of endometriosis and uterine fibroids on the risk of early death.

25 Nov 2024

Steritas announces collaboration with argenx to advance evidence for novel steroid-sparing therapeutics

Steritas LLC., a company dedicated to enhancing care for steroid-treated patients, today announced a licensing agreement with argenx, a global immunology company, for use of its STOX® Suite of steroid-toxicity clinical outcome assessments (COAs) across argenx's development programs for differentiated immunology therapeutics.

From Steritas LLC 25 Nov 2024

Enterprise Therapeutics publishes on medicinal chemistry of ETD001, a novel inhaled ENaC blocker for treatment of cystic fibrosis

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of people with respiratory diseases, today announced the publication of a peer reviewed study in The European Journal of Medicinal Chemistry.

From Enterprise Therapeutics Ltd 25 Nov 2024

Study points to a strategy for inhibiting hyper-progression of melanoma

Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead of unleashing the immune system to fight them.

25 Nov 2024

Study shows growing cancer treatment inequities between high and low-income countries

A recent analysis reveals striking disparities in the cost and availability of cancer drugs across different regions of the globe, with significant gaps between high- and low-income countries. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

25 Nov 2024

Could medical imaging innovation be the catalyst for precision medicine?

Precision medicine leverages genetic and lifestyle data to customize treatments, enhancing healthcare efficiency and patient outcomes in disease management.

24 Nov 2024

Golgi apparatus plays crucial role in enhancing T-cell function against cancer

The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell.

23 Nov 2024

Probiotics shown to mitigate effects of toxic fire-retardant chemicals

Polybrominated diphenyl ethers, or PBDEs, are fire-retardant chemicals that are found everywhere - upholstery, carpets, curtains, electronics, and even infant products.

23 Nov 2024

Barcelona launches world’s first joint program on evolutionary medical genomics

Three research institutions in Barcelona have teamed up to launch the world's first Joint Program on Evolutionary Medical Genomics.

22 Nov 2024

New oral peptide therapy offers hope for chronic abdominal pain

A research team at the University of Vienna, led by medicinal chemist Markus Muttenthaler, has developed a new class of oral peptide therapeutic leads for treating chronic abdominal pain.

22 Nov 2024

AI-designed drug ISM5939 granted IND clearance for cancer clinical trials

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announced that it has received IND clearance from FDA for ISM5939, a potential best-in-class oral small molecule inhibitor targeting ENPP1 for the treatment of solid tumors.

22 Nov 2024

Why predictive retina models could be the future of IND applications

Discover how retina models are revolutionizing rare disease treatment and accelerating drug development.

From Newcells Biotech 22 Nov 2024

New study unveils why glioblastoma becomes resistant to treatment

A new study from scientists at the UCLA Health Jonsson Comprehensive Cancer Center helps explain why glioblastoma, one of the most aggressive forms of brain cancer, becomes resistant to treatment, and introduces a new approach that paves the way for more personalized treatment strategies for patients with this deadly brain tumor.

22 Nov 2024

Short-term menopausal hormone therapy shows no long-term cognitive effects

Short-term menopausal hormone therapy (MHT) did not have long-term cognitive effects when given to women in early postmenopause, according to a study published November 21st in the open-access journal PLOS Medicine by Carey Gleason from the University of Wisconsin-Madison, USA, and colleagues.

22 Nov 2024

Cetuximab performs better than durvalumab in treating head and neck cancers

Head and neck cancers are the seventh most common type of cancer worldwide, according to the 2020 World Cancer Report. Smokers and drinkers, as well as those with HPV infections, are disproportionately affected.

22 Nov 2024

ESGCT Conference Takeaways: A specialty laboratory perspective

Discover the latest innovations in cell and gene therapy via Cerba Research's highlights of ESGCT.

From Cerba Research 22 Nov 2024

Experts recommend cascade screening over universal lipid screening for familial hypercholesterolemia

The German Institute for Quality and Efficiency in Health Care (IQWiG) was commissioned by the Federal Joint Committee (G-BA) to assess the benefit of universal blood lipid screening for the early detection of familial hypercholesterolemia in children and adolescents.

21 Nov 2024

Electrical stimulation may be essential for healthy tendons, study suggests

A new study by researchers at the University of Galway and the University of Limerick suggests that electrical stimulation might be essential for tendons to maintain their health, offering fresh possibilities in tendon repair and regeneration.

21 Nov 2024

Small brain-penetrating molecule offers hope for treating aggressive brain tumors

Gliocidin selectively kills glioblastoma cells by inhibiting nucleotide synthesis, showing potential as a therapeutic option in combination with temozolomide.

21 Nov 2024