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Old antibiotic nitroxoline suggested as a treatment for MPOX

In a recent study posted to the bioRxiv* server, researchers in Germany investigated the effectiveness of the antibiotic nitroxoline against the currently circulating mpox viruses, previously called monkeypox virus (MPXV). This antibiotic has been used in Europe for about fifty years and has been proven effective in fighting biofilm infections.

3 Jan 2023

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Announcing a new publication for Acta Materia Medica journal. Mass spectrometry imaging (MSI) has been shown to be a valuable tool through nearly every stage of the preclinical drug research and development (R&D) pipeline, and even to the early phase of clinical pharmaceutical evaluation.

3 Jan 2023

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry.

3 Jan 2023

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with poor prognosis and limited treatment options.

3 Jan 2023

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Announcing a new article publication for Zoonoses journal. This study was aimed at screening differentially expressed genes (DEGs) and exploring the potential immune mechanism induced by the Bacillus Calmette-Guerin (BCG) vaccine in a humanized mouse model.

3 Jan 2023

Researchers design educational course to inform practitioners on current ranges of ticks and disease risk

Anyone who enjoys taking walks through the woods or grassy fields when the weather is warm knows that checking for ticks afterward is a must.

3 Jan 2023

Working mothers shouldered more of the parenting burden during the pandemic, study finds

A first-of-its-kind study of parents' work arrangements during the pandemic shows that mothers working from home increased their supervisory parenting fully two hours more than fathers did, and women were also more likely to adapt their work schedules to new parenting demands.

3 Jan 2023

Salk scientists show how a microprotein can increase appetite in mice

Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that they have an important role in metabolism.

3 Jan 2023

Traditional Chinese medicine may help treat neurodegenerative diseases caused by HSV-1 reactivation

Announcing a new publication for Acta Materia Medica journal. Owing to environmental and lifestyle changes in modern society, physical and mental stress is on the rise among the population in attempting to compensate for the changes.

3 Jan 2023

Generous parental leave schemes protect against poorer mental health

Being on parental leave is protective against poorer mental health particularly among mothers, with evidence of this beneficial effect continuing in later life, according to a systematic review in The Lancet Public Health.

3 Jan 2023

The role of exosomes in osteosarcoma diagnosis, prognosis, and therapeutics

Announcing a new publication for Acta Materia Medica journal. Osteosarcoma, a primary malignant tumor of the skeleton, has a morbidity of 2.5 per 1 million people.

3 Jan 2023

New study to examine the effectiveness of stroke treatment for patients with disabilities

When conducting clinical research, investigators aim to control as many variables as possible so it is easier to examine the effectiveness of new treatments.

3 Jan 2023

Adolescents' habitual checking of social media could impact their brain development

In one of the first long-term studies on adolescent neural development and technology use, researchers at the University of North Carolina at Chapel Hill report adolescents' habitual checking of social media is linked with subsequent changes in how their brains respond to the world around them.

3 Jan 2023

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers."

3 Jan 2023

Subtle variations in every day cognitive performance associated with susceptibility to viral illness

If your alertness and reaction time is see-sawing more than usual, you may be more at risk of a viral illness.

3 Jan 2023

Olive oil is beneficial for maternal-fetal health

There have been numerous studies showing how olive oil affects pregnancy. In a recent study published in the journal Nutrition Research, evidence was gathered for its effects on fetomaternal outcomes. The results are interesting, suggesting a protective effect on these outcomes.

3 Jan 2023

Research News and Research

Old antibiotic nitroxoline suggested as a treatment for MPOX

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Researchers design educational course to inform practitioners on current ranges of ticks and disease risk

Working mothers shouldered more of the parenting burden during the pandemic, study finds

Salk scientists show how a microprotein can increase appetite in mice

Traditional Chinese medicine may help treat neurodegenerative diseases caused by HSV-1 reactivation

Generous parental leave schemes protect against poorer mental health

The role of exosomes in osteosarcoma diagnosis, prognosis, and therapeutics

New study to examine the effectiveness of stroke treatment for patients with disabilities

Adolescents' habitual checking of social media could impact their brain development

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

Subtle variations in every day cognitive performance associated with susceptibility to viral illness

Olive oil is beneficial for maternal-fetal health

Major update of the INCOG guidelines for cognitive rehabilitation following traumatic brain injury

Researchers discover new role of small RNAs in Salmonella infections

Benefits, challenges in the use of transcatheter pulmonary valve replacement for congenital heart disorders

Patients receive better care when specialists know referring physicians

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