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High levels of homocysteine, an amino acid in the blood, may indicate an increased risk of stroke

Observational studies measuring homocysteine concentrations in healthy individuals have found that, on average, those with high levels of homocysteine in their blood are more likely to have a stroke. But other factors that increase homocysteine concentration and stroke risk— such as smoking and socioeconomic class—may be responsible for the relationship observed in these studies, confounding the result.

13 Jan 2005

Gene transfer used to deliver antibodies to fight Anthrax

Using gene transfer technology, investigators were able to immunize mice against anthrax in just 12 hours, according to new research featured in the February 2005 issue of Molecular Therapy, the peer-reviewed scientific journal of the American Society of Gene Therapy (ASGT).

12 Jan 2005

Euro funding for diabetes and exercise research

Researchers at The University of Nottingham are among a network of European scientists who have been awarded €12.7 million (around £8.7 million) for a study into the relationship between lack of exercise and the development of diabetes — and the health benefits of regular exercise in its prevention and cure.

12 Jan 2005

Study links meat consumption to colon cancer

A major American Cancer Society study finds people who reported the highest consumption of red and processed meat had a significantly higher risk of colorectal cancer than those who reported the least consumption.

12 Jan 2005

No link between eating fruits and vegetables and a subsequent decreased risk for breast cancer

Contrary to findings in previous studies, new research that includes a large group of women found no link between eating fruits and vegetables and a subsequent decreased risk for breast cancer, according to a study in this week’s JAMA.

12 Jan 2005

Likelihood of a large number of future cases of vCJD remains small

According to research published today in Journal of the Royal Society Interface, the team believe there will be around 70 future cases of vCJD arising from the consumption of BSE-infected beef. At most this could rise to a total of around 600 deaths, although the researchers feel this is unlikely.

12 Jan 2005

Corticosteroids can be beneficial in the treatment of Duchenne muscular dystrophy

Corticosteroids can be beneficial in the treatment of Duchenne muscular dystrophy and can be offered as a treatment option, according to the American Academy of Neurology and the Child Neurology Society in a new practice guideline published in the January 11 issue of Neurology, the scientific journal of the American Academy of Neurology.

10 Jan 2005

Depression intensifies from one generation to the next

Nearly 60 percent of children whose parents and grandparents suffered from depression have a psychiatric disorder before they reach their early teens, according to a new study by researchers at Columbia University Medical Center (CUMC) and the New York State Psychiatric Institute (NYSPI).

10 Jan 2005

Scientists identify genes that promote the growth and recurrence of skin cancer

Andrzej Dlugosz, M.D., a professor of dermatology in the U-M Medical School, and colleagues at the University of Michigan and the National Cancer Institute examined the functions of the Hedgehog (Hh) signaling pathway in basal cell carcinoma – the most common form of cancer – and uncovered a subset of tumor cells that were resistant to inhibition of the Hedgehog pathway.

10 Jan 2005

Key genetic factor determines HIV/AIDS risk

People with more copies of a gene that helps to fight HIV are less likely to become infected with the virus or to develop AIDS than those of the same geographical ancestry, such as European Americans, who have fewer copies of the gene, according to a study funded by the National Institute of Allergy and Infectious Diseases (NIAID).

10 Jan 2005

Novel Structure Proteins (NSP) could help predict the possibility of tumor growth in a patient

A new family of genes called Novel Structure Proteins (NSP) discovered by researchers in the Sbarro Institute for Cancer Research and Molecular Medicine in Temple University’s College of Science and Technology could have the potential for predicting the possibility of tumor growth in a patient.

9 Jan 2005

Now significantly easier to search long stretches of DNA for genetic changes associated with disease

The researchers developed a method called direct genomic selection that accelerates the transition between family or population-based studies of disease inheritance patterns and identification of genetic variations that may contribute to disease.

6 Jan 2005

Discovery could lead to a screening test that identifies people who have a higher or lower susceptibility to HIV/AIDS

6 Jan 2005

Single abnormal cell can duplicate to form cancerous tumors

Researchers at the University of Pittsburgh have identified how a single aberrant cell can duplicate to form cancerous tumors, suggesting a specific protein mechanism as a target for the treatment of cancer, they report in a paper titled "Spindle Multipolarity Is Prevented by Centrosomal Clustering," published in the Jan. 7 issue of Science.

6 Jan 2005

Processes shed light on how DNA recombination mechanisms are related

Peter W. Atkinson, a University of California, Riverside professor of entomology and member of the university’s Institute for Integrative Genome Biology, is part of a team that has linked the movement of small pieces of DNA, known as transposable elements, to a process called V(D)J recombination that produces the genetic diversity responsible for the production of antibodies.

6 Jan 2005

Gene sequencing explains why natural bioremediation 'bug' has big appetite for chlorinated pollutants

"The born-to-dechlorinate bug" is what Cornell University researchers called Dehalococcoides ethenogenes Strain 195 when they found the bacterium obligingly detoxifying the pollutant PCE, or perchloroethylene (a chlorinated solvent used for dry cleaning), in sludge from an Ithaca, N.Y., sewage treatment plant.

6 Jan 2005

Scents and emotions linked by learning

Whether emotional responses to scent are a product of nature or nurture is a matter of scientific debate. But a Brown University study, published in the current issue of the International Journal of Comparative Psychology, comes down on the nurturing side.

6 Jan 2005