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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

Researchers discover important drug target for preventing blood cancer

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023

Researchers use a quick, portable process to produce promising virus-fighting protein

A multidisciplinary research team has produced a promising virus-fighting protein using a quick, portable process that could be easily deployed at the source of a future virus outbreak.

12 Apr 2023

Researchers conduct experiments comparing de novo proteins with computer-generated proteins

Proteins are components of every cell. How they have changed in the course of evolution for the purpose of taking on new functions in the body, has long been a subject of research.

12 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Study finds mobile antibiotic resistance genes in some probiotic bacteria, raising concerns for public health

Researchers examine antibiotic resistance genes and their mobility in Bifidobacteriales and Lactobacillales species.

11 Apr 2023

Cornell receives $9.5 million NIH grant for chronic fatigue research

A Cornell multidisciplinary research center that studies chronic fatigue syndrome has received a five-year, $9.5 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Disease – funding that will enable experts from disparate fields to work together on the mysterious and debilitating condition.

11 Apr 2023

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options.

11 Apr 2023

Study to measure the impact of whole genome sequencing in patients with cardiovascular disease

Henry Ford Health research teams are launching a series of clinical studies in partnership with Illumina Inc., a global leader in DNA sequencing and array-based technologies, to assess the impact of comprehensive genomic testing in various disease areas.

11 Apr 2023

Study expands the knowledge about gut viral diversity in healthy infants

Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.

11 Apr 2023

Prenatal and early childhood nutritional exposures: a review of the developmental contributions to obesity

Researchers reviewed the latest studies on nutritional exposures during prenatal and early childhood stages.

11 Apr 2023

How does e-cigarette vapor alter the gut microbiome, body weight, and systemic inflammation levels?

Researchers examine the effects of electronic cigarette (e-cigarette) vapor on gut microbiome, body weight, and systemic inflammation levels.

11 Apr 2023

Immunotherapy response in patients with advanced melanoma depends on prior treatments

Research led by scientists at UCLA Jonsson Comprehensive Cancer Center found that responses to a type of immunotherapy called PD-1 checkpoint blockade in patients with advanced melanoma depended on whether or not they had previously received another immunotherapy – CTLA-4 blockade – as well as other factors.

10 Apr 2023

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

In a recent study published in the Journal of the Alzheimer's Association (AA), researchers examined the effects of a low-carbohydrate-modified Mediterranean ketogenic diet (MMKD) on the gut microbiome and metabolome of patients at risk for Alzheimer's disease (AD).

9 Apr 2023

DPE analysis may help improve the diagnosis and management of colorectal cancer

A new editorial paper was published in Oncoscience (Volume 10) on March 23, 2023, entitled, "New method of clustering colorectal cancer patients using differential presence of exons (DPE) sequencing."

7 Apr 2023

New finding in roundworms upends classical thinking about animal cell differentiation

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

7 Apr 2023

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA. Since the discovery of the CRISPR gene editing technology, scientists are revealing the evolution of the CRISPR-Cas proteins from their precursors.

7 Apr 2023

New method estimates mutation risks due to residual radiation from the Fukushima nuclear disaster

Ionizing radiation from nuclear disasters are known to be harmful to the natural environment. The Fukushima Dai-ichi Nuclear Power Plant meltdown that occurred in 2011 is a prominent example of such a disaster in recent memory.

7 Apr 2023

New report seeks to uncover attitudes, challenges facing colorectal cancer awareness and screening

To uncover attitudes and the biggest challenges facing colorectal cancer (CRC) awareness and screening, BGI Genomics today released its State of Colorectal Cancer Awareness Report, marking the first-ever global survey report on the world's third most common cancer.

7 Apr 2023

DNA News and Research

Further Reading

Research reveals molecular features of rare mtDNA mutations

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

Researchers discover important drug target for preventing blood cancer

Researchers use a quick, portable process to produce promising virus-fighting protein

Researchers conduct experiments comparing de novo proteins with computer-generated proteins

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Study finds mobile antibiotic resistance genes in some probiotic bacteria, raising concerns for public health

Cornell receives $9.5 million NIH grant for chronic fatigue research

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Study to measure the impact of whole genome sequencing in patients with cardiovascular disease

Study expands the knowledge about gut viral diversity in healthy infants

Prenatal and early childhood nutritional exposures: a review of the developmental contributions to obesity

How does e-cigarette vapor alter the gut microbiome, body weight, and systemic inflammation levels?

Immunotherapy response in patients with advanced melanoma depends on prior treatments

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

DPE analysis may help improve the diagnosis and management of colorectal cancer

New finding in roundworms upends classical thinking about animal cell differentiation

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

New method estimates mutation risks due to residual radiation from the Fukushima nuclear disaster

New report seeks to uncover attitudes, challenges facing colorectal cancer awareness and screening

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