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FDA approves Humira (adalimumab) for Crohn's disease

The U.S. Food and Drug Administration (FDA) today approved Humira (adalimumab) to treat adult patients with moderately to severely active Crohn's disease, a chronic inflammatory disease of the intestines, which affects an estimated one million Americans.

27 Feb 2007

Gene therapy shows promise as treatment for diseased lower limbs at risk for amputation

New research suggests that gene therapy is a safe treatment method to explore in patients whose lower limbs are at risk for amputation because of poor circulation caused by blocked blood vessels.

27 Feb 2007

Genetic mutations make people susceptible to schizophrenia

Gene mutations governing a key brain enzyme make people susceptible to schizophrenia and may be targeted in future treatments for the psychiatric illness, according to MIT and Japanese researchers.

20 Feb 2007

More evidence that inflammation can fuel cancer

As evidence mounts that the body's normally protective inflammation response can drive some precancerous tissues to become fully malignant, UCSF scientists report discovering an apparent trigger to this potentially deadly process.

19 Feb 2007

Mechanism driving iron overload in thalassemia identified

Led by researchers at Weill Cornell Medical College in New York City, an international group of scientists has pinpointed a specific genetic relationship as the cause of dangerous iron overload in persons with a form of the inherited blood disease, beta-thalassemia.

14 Feb 2007

Dipeptidyl peptidase I critical for early growth of abdominal aortic aneurysms

Surgery is the only treatment for an abdominal aortic aneurysm, a weak spot in the body's main artery that dilates dangerously over time.

13 Feb 2007

Scientists find molecular cause for form of deafness

Scientists exploring the physics of hearing have found an underlying molecular cause for one form of deafness, and a conceptual connection between deafness and the organization of liquid crystals, which are used in flat-panel displays.

5 Feb 2007

Scientists change bird flu virus and stop it spreading

Scientists at the U.S. Centers for Disease Control and Prevention (CDC) have found that just two small changes in the virus that caused the 1918 Spanish flu pandemic stopped it from jumping between mammals in the laboratory.

4 Feb 2007

Corn, oats, cherries and red wine's high melatonin content can help delay ageing

The Spanish Ageing Research Network (Red Nacional de Investigación del Envejecimiento), funded by Carlos III Health Institute and headed by professor Darío Acuna Castroviejo, from the University of Granada, is very near to achieving one of today's Science greatest goals: allowing humans to age in the best possible health conditions.

31 Jan 2007

First estimate at number of genes determining growth rate in any animal

How many genes influence a complex trait, like weight, height or body type?

30 Jan 2007

Melanin concentrating hormone found to be involved with insulin production

A new Joslin Diabetes Center-led study has shown conclusively that a neuropeptide, melanin concentrating hormone (MCH), found in the brain and known for its role in increasing appetite in people, plays a role in the growth of insulin-producing beta cells and the secretion of insulin.

28 Jan 2007

An active mind delays the onset of Alzheimer's

Learning appears to slow the development of two brain lesions that are the hallmarks of Alzheimer's disease, scientists at UC Irvine have discovered. The finding suggests that the elderly, by keeping their minds active, can help delay the onset of this degenerative disease.

23 Jan 2007

Targeting of cancer cells with ferrimagnetic ferritin cage nanoparticles

Researchers at Montana State University have used an engineered form of ferritin, a cage-like iron storage protein, to both synthesize and deliver iron oxide nanoparticles to tumors.

16 Jan 2007

New approach offers hope for an effective herpes vaccine

A researcher at Montana State University has called for an innovative, new approach in developing a vaccine against genital herpes.

10 Jan 2007

Emory University announces new health institute

Emory University announced today a new Global Health Institute that will help address the most pressing health challenges around the world, particularly in poorer nations.

10 Jan 2007

Modified skin cells that may help protect cultured skin substitutes from infection

Cincinnati burn researchers have created genetically modified skin cells that, when added to cultured skin substitutes, may help fight off potentially lethal infections in patients with severe burns.

9 Jan 2007

Genetically engineered blood protein can be used to split water into oxygen and hydrogen

Scientists have combined two molecules that occur naturally in blood to engineer a molecular complex that uses solar energy to split water into hydrogen and oxygen, says research published in the Journal of the American Chemical Society.

2 Dec 2006

Safety of t-PA clot-busting therapy questioned

Across the world, emergency medical teams often administer a powerful clot-busting drug called tissue plasminogen activator (t-PA) to help patients stricken by heart attack.

13 Nov 2006

Phase I clinical trial of experimental gene therapy to treat HIV shows encouraging results

The results of a Phase I clinical trial of an experimental gene therapy aimed at treating HIV indicate that the therapy is safe and effective and also might sustain viral loads, according to a study published on Monday in the online edition of the Proceedings of the National Academy of Sciences, the AP/Washington Post reports.

8 Nov 2006

Scientists discover how androgen plays a role in the development of prostate cancer

Scientists have discovered for the first time a specific biochemical pathway by which the sex hormone, androgen, increases levels of harmful chemicals called reactive oxygen species (ROS) in the prostate gland that play a role in the development of prostate cancer.