Therapeutics News and Research

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Researchers identify new drug that makes pancreatic cancer cells more vulnerable to chemotherapy

Researchers at Washington University School of Medicine in St. Louis have identified a drug compound that makes pancreatic cancer cells more vulnerable to chemotherapy.

1 Dec 2021

Plant-derived virus-like particle vaccines against SARS-CoV-2

In a review published in Biotechnology Letters, the authors discuss plant-derived VLP-based vaccines.

1 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Study shows long-term safety and biologic activity of golodirsen in DMD patients

This first-in-human study of golodirsen showed its long-term safety and biologic activity in patients with Duchenne Muscular Dystrophy (DMD). The approved exon-skipping therapy is designed to enable the production of functional dystrophin proteins, as described in the peer-reviewed journal Nucleic Acid Therapeutics.

1 Dec 2021

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN Bio 1 Dec 2021

Nanoengineers develop a new approach to effectively deliver mRNA into cells

Nanoengineers at the University of California San Diego have developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells.

30 Nov 2021

An antiviral regimen based on biomimetic polymers for COVID-19

In a new study published on the bioRxiv* preprint server, scientists proposed the aforementioned mechanism of action (MOA) and have validated it using electron photomicrographs of murine cytomegalovirus (MCMV), which were incubated with a nanoviricide.

30 Nov 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

New strategy for antibodies to distort viruses discovered

It is widely understood that antibodies neutralize viruses by latching onto their surfaces and blocking them from infecting host cells.

30 Nov 2021

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

There are few treatment options for children with multiple sclerosis - a condition in which the immune system attacks the protective covering of nerves in the brain and spinal cord - and most therapies for the disease have not been tested in children.

30 Nov 2021

New safe, painless diagnostic tool for detecting breast cancer

Mammograms are a safe, effective way to detect the presence of breast cancer in women. But doctors recommend most females should start getting mammograms after the age of 40 in part because the procedure involves small doses of ionizing radiation.

30 Nov 2021

Omicron and other coronavirus variants: What you need to know

Americans, already weary of a pandemic nearly two years long, were dealt a new blow during the long Thanksgiving weekend: the announcement that a new coronavirus variant had emerged.

30 Nov 2021

From tiny particles to big success: Knauer awarded the innovation prize for Berlin Brandenburg

The producer of high-tech laboratory systems, KNAUER Wissenschaftliche Geräte GmbH was awarded the prestigious Innovation Prize for the Berlin Brandenburg region for their new system for the production of lipid nanoparticles (LNPs).

From KNAUER Wissenschaftliche Geräte GmbH 30 Nov 2021

SARS-CoV-2 Delta spike increases viral virulence and inflammatory cytokine production

In a new study published on the bioRxiv* preprint server, scientists investigated several virological features of the Delta spike protein.

29 Nov 2021

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Funded by a Specialized Program of Research Excellence award from the National Cancer Institute (NCI), the Kidney Cancer Program at UT Southwestern's Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

29 Nov 2021

An update of what is currently known about Omicron

On 26 November 2021, WHO designated the variant B.1.1.529 a variant of concern, named Omicron, on the advice of WHO's Technical Advisory Group on Virus Evolution (TAG-VE).

29 Nov 2021

Heart failure patients may benefit from common type 2 diabetes drug

Dapagliflozin, a drug commonly used to treat type 2 diabetes, improved symptoms and physical limitations in patients with heart failure with preserved ejection fraction, according to clinical trial results published in Nature Medicine.

29 Nov 2021

UC San Diego's Scott Lippman to launch and lead NCI-sponsored PreCancer Genome Atlas

Scott Lippman, MD, will launch and lead the PreCancer Genome Atlas, a National Cancer Institute (NCI)-sponsored effort to map in time and space all of the molecular, cellular and structural characteristics of premalignant lesions and how they evolve into invasive cancers.

29 Nov 2021

SARS-CoV-2 can directly invade human kidney cells, research shows

Up to 25% of patients' COVID-19 cases involve acute kidney injury—the kidneys' equivalent of a heart attack.

29 Nov 2021

SARS-CoV-2 Omicron variant: What we know so far

On November 24, 2021, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) variant was first reported to the World Health Organization (WHO) from South Africa.

28 Nov 2021

Therapeutics News and Research

Researchers identify new drug that makes pancreatic cancer cells more vulnerable to chemotherapy

Plant-derived virus-like particle vaccines against SARS-CoV-2

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

Study shows long-term safety and biologic activity of golodirsen in DMD patients

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

Nanoengineers develop a new approach to effectively deliver mRNA into cells

An antiviral regimen based on biomimetic polymers for COVID-19

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

New strategy for antibodies to distort viruses discovered

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

New safe, painless diagnostic tool for detecting breast cancer

Omicron and other coronavirus variants: What you need to know

From tiny particles to big success: Knauer awarded the innovation prize for Berlin Brandenburg

SARS-CoV-2 Delta spike increases viral virulence and inflammatory cytokine production

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

An update of what is currently known about Omicron

Heart failure patients may benefit from common type 2 diabetes drug

UC San Diego's Scott Lippman to launch and lead NCI-sponsored PreCancer Genome Atlas

SARS-CoV-2 can directly invade human kidney cells, research shows

SARS-CoV-2 Omicron variant: What we know so far

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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