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New software-based method identifies patients with newly diagnosed HIV using EMRs

A new, validated software-based method for identifying patients with newly diagnosed HIV using electronic medical records (EMRs) is described in AIDS Research and Human Retroviruses, a peer-reviewed journal published by Mary Ann Liebert, Inc., publishers.

16 Jul 2014

Tamoxifen gel stops breast cancer growth without causing dangerous side effects

A gel form of tamoxifen applied to the breasts of women with noninvasive breast cancer reduced the growth of cancer cells to the same degree as the drug taken in oral form but with fewer side effects that deter some women from taking it, according to new Northwestern Medicine- research.

16 Jul 2014

New study reveals how genetic defect may make people more susceptible to developing melanoma

A new study by University of Kentucky researchers shows how a genetic defect in a specific hormonal pathway may make people more susceptible to developing melanoma, the deadliest type of skin cancer.

16 Jul 2014

Inflammatory shift in long-standing bipolar disorder

Patients with chronic bipolar disorder, but not those with schizophrenia, have a shift towards an M1 rather than an M2 macrophage response, research suggests.

15 Jul 2014

New method for identifying patients with newly diagnosed HIV using electronic medical records

15 Jul 2014

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

Advanced Cell Diagnostics Inc. (ACD), a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools, has announced that its RNAscope® RNA in situ hybridization technology has reached two major milestones. In just three years, over 100 peer-reviewed papers featuring the technology have been published, and with the significant increase in use of RNAscope, ACD has now built a library of over 4000 target probes for numerous species. Probes are designed to order in under two weeks, and in just six months the library has grown by over 1500, reflecting the wide interest in ACD’s breakthrough technology.

From Advanced Cell Diagnostics 15 Jul 2014

Johnson & Johnson sales increase 9.1% to $19.5 billion in second quarter 2014

Johnson & Johnson today announced sales of $19.5 billion for the second quarter of 2014, an increase of 9.1% as compared to the second quarter of 2013. Operational results increased 9.4% and the negative impact of currency was 0.3%.

15 Jul 2014

Pfizer to in-license Absorption Systems' BCRP-MDCK cells

Absorption Systems, a leader in novel test systems for drug transporters, announces a license agreement with Pfizer Inc., in which Pfizer will in-license Absorption Systems' BCRP-MDCK cells. This cell line is stably transfected with the human ABCG2 gene, which codes for a protein known as BCRP (breast cancer resistance protein).

15 Jul 2014

Metvix PDT now available at Odette Cancer Centre as additional treatment option for NMSC patients

The Odette Cancer Centre at Sunnybrook Health Sciences Centre in conjunction with Galderma Canada are pleased to announce that Metvix PDT (Photodynamic Therapy), is now available at the Odette Cancer Centre in Toronto as an additional treatment option for patients with NMSC (non-melanoma skin cancer).

15 Jul 2014

Scientists show how cannabis could reduce tumor growth in cancer patients

Scientists at the University of East Anglia have shown how the main psychoactive ingredient in cannabis could reduce tumor growth in cancer patients.

15 Jul 2014

New role for cholesterol in activation of cellular signaling pathway that linked to cancer

Everyone knows that cholesterol, at least the bad kind, can cause heart disease and hardening of the arteries. Now, researchers at the University of Illinois at Chicago describe a new role for cholesterol in the activation of a cellular signaling pathway that has been linked to cancer.

15 Jul 2014

Research demonstrates new computer software to help diagnose cancer cells

In pathology, cells and cell nuclei are usually examined using a microscope for bio-marker expressions in tumours. This analysis is used to weigh up the treatment options for patients who have cancer, for example.

15 Jul 2014

DARPins could revolutionize protein therapeutics

Integrating an INTEGRA VIAFLO 96 multichannel pipette into their high throughput expression facility has enabled Molecular Partners (Zurich, Switzerland) to streamline the discovery and development of a novel class of targeted protein therapeutics termed DARPins.

From INTEGRA Biosciences 15 Jul 2014

New potential avenues to predict and prevent ovarian cancer metastasis

Circulating tumor cells spread ovarian cancer through the bloodstream, homing in on a sheath of abdominal fatty tissue where it can grow and metastasize to other organs, scientists at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

15 Jul 2014

Researchers develop new software to identify severity of cancer

Together with the company Tissuegnostics, the pathologist Lukas Kenner and his colleagues have developed a software that is able to identify cancer cells in tissue sections and demonstrate the presence of specific biomarkers on cells. The overall information provides a precise picture of the disease and leads to the most suitable treatment.

15 Jul 2014

CRISPR system involved in promoting antibiotic resistance

CRISPR, a system of genes that bacteria use to fend off viruses, is involved in promoting antibiotic resistance in Francisella novicida, a close relative of the bacterium that causes tularemia.

15 Jul 2014

A*STAR, Roche partner to identify novel drug targets for cancer treatment

A*STAR's Bioprocessing Technology Institute has entered into an agreement with one of the world's largest pharmaceutical company, Roche, to identify novel drug candidates for the detection and treatment of cancer.

15 Jul 2014

Study reveals why survival for blood cancer patients still varies between regions within Europe

Failure to get the best treatment and variations in the quality of care are the most likely reasons why survival for blood cancer patients still varies widely between regions within Europe, according to the largest population-based study of survival in European adults to date, published in The Lancet Oncology.

15 Jul 2014

New theory of how cancer works could lead to next generation of treatments of disease

A new theory of how cancer works could lead to the next generation of treatments of the disease. The theory suggests that cancer forms when recently evolved genes are damaged, and cells have to revert to using older, inappropriate genetic pathways.

15 Jul 2014

Acute glaucoma is largely an inflammatory disease, say researchers

Researchers at the University of California, San Diego School of Medicine and Sun Yat-sen University in China have shown that acute glaucoma in mice is largely an inflammatory disease and that high pressure in the eye causes vision loss by setting in motion an inflammatory response similar to that evoked by bacterial infections.

14 Jul 2014

B Cell News and Research

New software-based method identifies patients with newly diagnosed HIV using EMRs

Tamoxifen gel stops breast cancer growth without causing dangerous side effects

New study reveals how genetic defect may make people more susceptible to developing melanoma

Inflammatory shift in long-standing bipolar disorder

New method for identifying patients with newly diagnosed HIV using electronic medical records

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

Johnson & Johnson sales increase 9.1% to $19.5 billion in second quarter 2014

Pfizer to in-license Absorption Systems' BCRP-MDCK cells

Metvix PDT now available at Odette Cancer Centre as additional treatment option for NMSC patients

Scientists show how cannabis could reduce tumor growth in cancer patients

New role for cholesterol in activation of cellular signaling pathway that linked to cancer

Research demonstrates new computer software to help diagnose cancer cells

DARPins could revolutionize protein therapeutics

New potential avenues to predict and prevent ovarian cancer metastasis

Researchers develop new software to identify severity of cancer

CRISPR system involved in promoting antibiotic resistance

A*STAR, Roche partner to identify novel drug targets for cancer treatment

Study reveals why survival for blood cancer patients still varies between regions within Europe

New theory of how cancer works could lead to next generation of treatments of disease

Acute glaucoma is largely an inflammatory disease, say researchers

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