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Study characterizes SARS-CoV-2 spike-specific cluster of differentiation 4+ T-cell response

In a new study, researchers characterized over 100 SARS-CoV-2-specific CD4+ T-cell epitopes.

8 Apr 2022

The effects of SARS-CoV-2 infection in different ancestry origins from the same region

Researchers examined whether varied allelic frequencies of the HLA gene in people of different ancestral origins were associated with increased susceptibility to SARS-CoV-2 infection and disease severity.

4 Apr 2022

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists discuss the pathogenic characteristics of SARS-CoV-2 and available therapeutic interventions for treating COVID-19.

3 Apr 2022

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Researchers developed a novel high-throughput method to obtain monoclonal antibodies from COVID-19 individuals infected with SARS-CoV-2 ancestral strain Wuhan-Hu-1 and the Beta or Gamma variants.

1 Apr 2022

Study finds COVID-19 convalescent children had more robust humoral immune responses to SARS-CoV-2 than convalescent adults

The work investigated why the children experienced milder COVID-19 illness even after a strong immune response.

1 Apr 2022

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Researchers discuss the use of the isothiocyanate sulforaphane for the treatment of both SARS-CoV-2 and HCoV-OC43 infections.

30 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.

29 Mar 2022

Immune response dynamics following COVID-19 heterologous and homologous vaccinations

Researchers evaluated the cellular and humoral immunity following heterologous and homologous COVID-19 immunization regimens for up to five months.

29 Mar 2022

Is SARS-CoV-2 a Superantigen?

Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), scientists have been conducting extensive studies to understand various aspects of the virus. Researchers have stated that SARS-CoV-2 manifests several biological and clinical consequences of a superantigen

29 Mar 2022

One year after severe COVID-19, T cells persist against SARS-CoV-2

In a recently published article in the journal eBioMedicine, scientists have demonstrated that critically ill coronavirus disease 2019 (COVID-19) patients are capable of generating durable memory T cell response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for more than one year after hospital discharge.

28 Mar 2022

HIV patients on antiretroviral treatment with protease inhibitors may have lower COVID-19 risk

A preliminary study to be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases in Lisbon, Portugal (23-26 April), suggests that people living with HIV who are on antiretroviral treatment (ART) with protease inhibitors (PI), may have a lower risk of COVID-19 infection.

27 Mar 2022

Study evaluates humoral and cellular immune memory induced by different COVID-19 vaccines

Researchers evaluated the humoral and cellular immune memory induced by four COVID-19 vaccines representing three different vaccine platforms.

24 Mar 2022

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

23 Mar 2022

CD4 News and Research

Study characterizes SARS-CoV-2 spike-specific cluster of differentiation 4+ T-cell response

The effects of SARS-CoV-2 infection in different ancestry origins from the same region

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Study finds COVID-19 convalescent children had more robust humoral immune responses to SARS-CoV-2 than convalescent adults

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

Immune response dynamics following COVID-19 heterologous and homologous vaccinations

Is SARS-CoV-2 a Superantigen?

One year after severe COVID-19, T cells persist against SARS-CoV-2

HIV patients on antiretroviral treatment with protease inhibitors may have lower COVID-19 risk

Study evaluates humoral and cellular immune memory induced by different COVID-19 vaccines

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

IU researchers exploring new ways to treat seasonal or intermittent asthma

Sex-specific differences in T-cell responses to COVID-19

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Study shows BCG vaccination reduces SARS-CoV-2-induced lung inflammation in hamsters

Immuno-metabolomic signatures that correlate with antigen-specific-T cell response during active COVID-19

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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