Central Nervous System News and Research

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New advisory offers evidence-based strategies to prevent postoperative delirium in older adults

Delirium and cognitive decline are common complications of anesthesia and surgery in older adults.

10 Dec 2024

Heart medication may slow the progression of Huntington's disease

Research indicates β-blockers may reduce the risk of motor diagnosis and slow symptom progression in Huntington's disease, suggesting new management approaches.

4 Dec 2024

CU Anschutz Medical Campus receives $46 million for blindness cure research

The University of Colorado Anschutz Medical Campus will receive up to $46 million from the Advanced Research Projects Agency for Health (ARPA-H) Transplantation of Human Eye Allografts (THEA) program to advance pioneering research aimed at curing total blindness through human eye transplantation.

2 Dec 2024

Study reveals effects of temporary blood flow loss on blood vessels in hypertensive rats

A study coordinated by Dr Francesc Jiménez-Altayó, researcher at the Institut de Neurociències of the UAB (INc-UAB) and at CIBERCV, shows that temporary lack of blood flow to the brain can lead to lasting changes in the small arteries of the abdomen in rats with high blood pressure.

28 Nov 2024

How neural and hormonal gut-brain communication shapes metabolism and health

Interoception research reveals how gut-brain communication via neural, hormonal, and microbial pathways regulates metabolism, hunger, and overall health, offering insights for therapeutic innovations.

25 Nov 2024

New discovery in the peripheral nervous system could help control obesity

An international team of researchers has discovered a new component of the peripheral nervous system that acts by increasing energy metabolism in the body.

25 Nov 2024

Researchers develop new approach to effectively deliver therapeutics into the brain

Researchers at the Icahn School of Medicine at Mount Sinai have developed an innovative approach - demonstrated in mouse models and isolated human brain tissue - to safely and effectively deliver therapeutics into the brain, providing new possibilities for treating a wide range of neurological and psychiatric diseases.

25 Nov 2024

New oral peptide therapy offers hope for chronic abdominal pain

A research team at the University of Vienna, led by medicinal chemist Markus Muttenthaler, has developed a new class of oral peptide therapeutic leads for treating chronic abdominal pain.

22 Nov 2024

AI-designed drug ISM5939 granted IND clearance for cancer clinical trials

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announced that it has received IND clearance from FDA for ISM5939, a potential best-in-class oral small molecule inhibitor targeting ENPP1 for the treatment of solid tumors.

22 Nov 2024

Oral medication sodium oxybate shows promise for treating laryngeal dystonia

Laryngeal dystonia (LD), a rare neurological disease that significantly impacts a person's ability to speak due to uncontrollable vocal cord spasms, can have a debilitating effect on a person's social life, employment and mental health.

20 Nov 2024

Impact of glucagon-like peptide-1 receptor agonists on alcohol consumption

The impact of GLP-1 RAs on alcohol use is explored, showing potential benefits in reducing intake and cravings, but with mixed results from clinical trials.

19 Nov 2024

Metagenomic sequencing improves detection of rare pathogens in CNS infections

New research shows that metagenomic next-generation sequencing (mNGS) over seven years increased pathogen detection in challenging CNS infections, identifying rare and unexpected microbes often missed by standard testing.

13 Nov 2024

AI tool tracks infant movement to predict neurologic changes in NICU

A team of clinicians, scientists, and engineers at Mount Sinai trained a deep learning pose-recognition algorithm on video feeds of infants in the neonatal intensive care unit (NICU) to accurately track their movements and identify key neurologic metrics.

11 Nov 2024

Key kinase involved in cell division linked to abnormal blood vessel growth in genetic disorder

Inhibition of CDK6 may prevent arteriovenous malformations in hereditary hemorrhagic telangiectasia by regulating endothelial cell cycle progression.

8 Nov 2024

Spatial transcriptomics uncovers tissue niches in multiple sclerosis

Mapping cell types in MS lesions reveals unique tissue niches and interactions, offering insights into the molecular drivers of multiple sclerosis progression.

8 Nov 2024

Understanding the role of neuroimmune cells in brain health and disease

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system.

6 Nov 2024

Elevated antibody responses to Epstein-Barr virus linked to increased risk of multiple sclerosis

Researchers identified a unique antibody signature against the Epstein-Barr virus protein EBNA1 that correlates with cross-reactive immune responses in multiple sclerosis (MS) patients. This connection provides new insights into how EBV infection may drive MS pathogenesis.

5 Nov 2024

Central Nervous System News and Research

New advisory offers evidence-based strategies to prevent postoperative delirium in older adults

Heart medication may slow the progression of Huntington's disease

CU Anschutz Medical Campus receives $46 million for blindness cure research

Study reveals effects of temporary blood flow loss on blood vessels in hypertensive rats

How neural and hormonal gut-brain communication shapes metabolism and health

New discovery in the peripheral nervous system could help control obesity

Researchers develop new approach to effectively deliver therapeutics into the brain

New oral peptide therapy offers hope for chronic abdominal pain

AI-designed drug ISM5939 granted IND clearance for cancer clinical trials

Oral medication sodium oxybate shows promise for treating laryngeal dystonia

Impact of glucagon-like peptide-1 receptor agonists on alcohol consumption

Metagenomic sequencing improves detection of rare pathogens in CNS infections

AI tool tracks infant movement to predict neurologic changes in NICU

Key kinase involved in cell division linked to abnormal blood vessel growth in genetic disorder

Spatial transcriptomics uncovers tissue niches in multiple sclerosis

Understanding the role of neuroimmune cells in brain health and disease

Elevated antibody responses to Epstein-Barr virus linked to increased risk of multiple sclerosis

Researchers develop the first polymer-based therapeutic for Huntington’s disease

Space-grown stem cells show promise for accelerating biotherapies

New study identifies potential treatment for tauopathies using carbonic anhydrase inhibitors

Event guide: The 7th CNS Drug Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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