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Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

Solidifying its Leadership Position in Clinical Flow Cytometry, Beckman Coulter Life Sciences Receives IVDR Certification Covering More than 200 Flow Cytometry Reagents

Leading the way with the industry’s largest portfolio of CE-IVD labeled flow cytometry reagents in the market, Beckman Coulter Life Sciences announces that it has received a EU Quality Management System Certificate under the new In Vitro Diagnostic Medical Devices Regulation (IVDR) for more than 200 flow cytometry reagents developed and manufactured at their Marseille, France facility.

From Beckman Coulter Life Sciences - Flow Cytometry 20 Jan 2022

Scientists assess ACE2 binding and antigenicity of Mu (B.1.621) and A.2.5 spikes

To gain a better understanding of the antigenic properties of Mu and A.2.5 Spikes, Canadian scientists evaluated their capacity to interact with ACE2 and performed binding and neutralization assays with plasma from vaccinated individuals.

18 Jan 2022

PhoreMost expands into new facility at Unity Campus, Cambridge, UK

PhoreMost Ltd today announced it has relocated its headquarters to Unity Campus, a high-specification technology and innovation park.

From PhoreMost 18 Jan 2022

Specific immunoresponse to SARS-CoV-2 in cats and dogs housed with COVID-19 patients

Researchers conducted a detailed epitope mapping of Np and developed an experimental double antigen-based ELISA.

13 Jan 2022

Assessing how autoantibodies in COVID-19 correlate with anti-viral humoral responses

Researchers screen several systemic autoantibodies to assess their association with the severity of COVID-19.

13 Jan 2022

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

In the present study, researchers isolated an infectious AY.4.2 strain of COVID-19 from the nasopharyngeal swab of a symptomatic individual from the Paris region. Then, they introduced the AY.4.2 signature mutations - T95I, Y145H, and A222V - in an expression plasmid coding the Delta protein to study the function of the AY.4.2 S protein.

13 Jan 2022

The impact of Comirnaty vaccination on the levels of PEG specific antibodies

Researchers observe an increase in PEG antibodies following vaccination with the SARS-CoV-2 mRNA lipid nanoparticle vaccine.

12 Jan 2022

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

In a new study, researchers determined the early immune response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) during mild coronavirus disease 2019 (COVID-19) in rhesus macaques.

11 Jan 2022

SARS-CoV-2 activates microglia in the brain

Researchers demonstrate that SARS-CoV-2 can infect the human microglia.

10 Jan 2022

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

A new study posted to the pre-print server medRxiv* investigated the significant immune alterations concerning SARS-CoV-2 specific innate and adaptive immunity associated with a lower BNT162b2 mRNA vaccine response in older individuals.

10 Jan 2022

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Biliary atresia is a rare disease that occurs when a delicate tree-like set of ducts that carry bile from the liver to the intestine becomes scarred and blocked. While some treatments can slow the damage, most children who develop biliary atresia will die without a liver transplant.

10 Jan 2022

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

New research suggests that viral mutations have a minimal effect on T cell immunity, which could explain the protection provided by vaccination against severe COVID-19, despite the significant loss of neutralizing antibodies.

10 Jan 2022

SARS-CoV-2 Omicron variant uses endosomal entry pathway and grows in upper respiratory tract cells

Researchers demonstrate that the SARS-CoV-2 Omicron variant grows rapidly in human primary nasal epithelial cultures.

9 Jan 2022

Researchers investigate SARS-CoV-2 specific inflammatory response

New research can confirm that while some of the response from monocytes to SARS-CoV-2 is generic to virus infection, most of it SARS-CoV-2 specific, especially proinflammatory responses.

7 Jan 2022

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Not too long ago the idea of taking, for instance a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

6 Jan 2022

Cytometry News and Research

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

Solidifying its Leadership Position in Clinical Flow Cytometry, Beckman Coulter Life Sciences Receives IVDR Certification Covering More than 200 Flow Cytometry Reagents

Scientists assess ACE2 binding and antigenicity of Mu (B.1.621) and A.2.5 spikes

PhoreMost expands into new facility at Unity Campus, Cambridge, UK

Specific immunoresponse to SARS-CoV-2 in cats and dogs housed with COVID-19 patients

Assessing how autoantibodies in COVID-19 correlate with anti-viral humoral responses

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

The impact of Comirnaty vaccination on the levels of PEG specific antibodies

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

SARS-CoV-2 activates microglia in the brain

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

SARS-CoV-2 Omicron variant uses endosomal entry pathway and grows in upper respiratory tract cells

Researchers investigate SARS-CoV-2 specific inflammatory response

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

After SARS-CoV-2 booster dose memory B cells adapt to Omicron

Production of molecular probes of spike and subdomains for all SARS-CoV-2 variants

T-cell responses to SARS-CoV-2 Omicron variant confer protection to vaccinated individuals

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

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