Developmental Biology News and Research

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Mea6 elimination in oligodendrocytes impairs white matter structure and lipid content

More than half amount in adult human brain is made up of white matter. Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons to form the major components of white matter.

27 Mar 2023

Research shows the role of PCYT2-mediated lipid synthesis in vertebrate muscle health

Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway.

20 Mar 2023

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

Neutral or awkward behavior of mothers with infants linked to an epigenetic change in children

Adding evidence to the importance of early development, a new study links neutral maternal behavior toward infants with an epigenetic change in children related to stress response.

2 Mar 2023

Novel software tool helps analyze animal behaviors

A team from the University of Michigan has developed a new software tool to help researchers across the life sciences more efficiently analyze animal behaviors.

25 Feb 2023

Novel fatty liver organoid models could aid in drug discovery and testing

Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology established novel human organoid models of fatty liver disease.

23 Feb 2023

Researchers identify a novel mechanism of DNA repair that occurs in neurons

"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age.

15 Feb 2023

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

Five teams led by Weill Cornell Medicine scientists have been awarded funding from the Starr Cancer Consortium in its 16th annual grant competition.

10 Feb 2023

High-precision mechanical sensing system can measure in vivo biomechanical properties of tissue, single cell

Fiber sensing scientists at Shenzhen University have developed a compact fiber optical nanomechanical probe (FONP) for measuring in vivo biomechanical properties of tissue and even single cell.

10 Feb 2023

Molecular switch regulates autophagy in plants

Autophagy, or "self-eating", is an essential cellular quality control mechanism that clears the cell of protein aggregates and damaged organelles. This mechanism is inactive under normal conditions and only triggered upon persistent cellular stress.

10 Feb 2023

Computer software can predict what happens when certain gene networks are disrupted

Computer software developed at Washington University School of Medicine in St. Louis can predict what happens to complex gene networks when individual genes are missing or dialed up more than usual.

9 Feb 2023

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

A mutant or damaged gene may be a cause of a severe, mysterious form of nonalcoholic fatty liver disease, University of Illinois Urbana-Champaign researchers have found.

9 Feb 2023

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

In this interview, we speak to Magdalena Kasendra at the CuSTOM Accelerator, about the organoid technology and how it has the power the revolutionize healthcare.

From Society for Laboratory Automation and Screening (SLAS) 1 Feb 2023

Study uncovers protein that acts as a brake for DNA replication

A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study by Weill Cornell Medicine researchers.

24 Jan 2023

Study reveals how new cells join existing tissues by reading mechanical information

Integration is not only a problem of social significance among humans, but also an issue for the cells that form us as humans.

12 Jan 2023

UC research could lead to possible treatments for scoliosis in the future

How cells shape complex tissues and organs during embryo development, which makes us what we are, has many mysteries.

11 Jan 2023

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine.

28 Dec 2022

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

A Japanese research group has become the first to reveal that the checkerboard-like arrangement of cells in the inner ear's organ of Corti is vital for hearing.

27 Dec 2022

Adding Gli1+ cells could regenerate the enthesis after rotator cuff surgery

In the annals of shoulder surgery, NFL quarterback Drew Brees is an anomaly. In 2005, Brees was tackled and the rotator cuff tendon in his throwing shoulder was severely torn, a potentially career-ending injury.

16 Dec 2022

Researchers discover how segmentation clock genes instruct the tempo of spine formation

One of the most dramatic phases of fetal development occurs as previously unstructured collections of rapidly dividing precursor cells begin forming the embryo's spine.

15 Dec 2022

Developmental Biology News and Research

Mea6 elimination in oligodendrocytes impairs white matter structure and lipid content

Research shows the role of PCYT2-mediated lipid synthesis in vertebrate muscle health

Discovery could lead to effective treatments for acute alcohol intoxication

Neutral or awkward behavior of mothers with infants linked to an epigenetic change in children

Novel software tool helps analyze animal behaviors

Novel fatty liver organoid models could aid in drug discovery and testing

Researchers identify a novel mechanism of DNA repair that occurs in neurons

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

High-precision mechanical sensing system can measure in vivo biomechanical properties of tissue, single cell

Molecular switch regulates autophagy in plants

Computer software can predict what happens when certain gene networks are disrupted

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

Study uncovers protein that acts as a brake for DNA replication

Study reveals how new cells join existing tissues by reading mechanical information

UC research could lead to possible treatments for scoliosis in the future

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

Adding Gli1+ cells could regenerate the enthesis after rotator cuff surgery

Researchers discover how segmentation clock genes instruct the tempo of spine formation

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