Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

Study characterizes brain changes in adolescents affected by juvenile fibromyalgia

Juvenile fibromyalgia is a syndrome characterized by a chronic pain affecting the whole body. It also causes fatigue as well as sleep and mood disorders.

17 Feb 2022

Use of immunosuppressants for inflammatory rheumatic diseases and the associated risk of severe COVID-19

A recent study posted to the medRxiv* preprint server investigated the risk of severe/fatal coronavirus disease 2019 (COVID-19) in patients treated with immunosuppressants for inflammatory rheumatic diseases (IRD).

15 Feb 2022

Colchicine holds promise to reduce the risk of severe COVID-19

A recent article, published in Rheumatology and Therapy, reviews the potent evidence of colchicine against the SARS-CoV-2 infection.

7 Feb 2022

Study investigates how vitamin D or omega fatty acids may affect rates of autoimmune diseases

Autoimmune diseases (AD) such as rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis, are a leading cause of morbidity and mortality as people age.

28 Jan 2022

Immunosuppressed patients can benefit from COVID-19 booster vaccination, study shows

Patients under immunosuppressive therapy, who do not respond to primary COVID-19 vaccination, have an increased risk for severe COVID-19 disease courses. Until now, it was not clear whether those patients at risk can benefit from an additional booster vaccination.

26 Jan 2022

New, more accurate tool to measure the progress of lupus in patients

A new paper in Rheumatology, published by Oxford University Press, indicates that researchers have developed a new, easier, and more accurate tool to measure the progress of lupus in patients.

25 Jan 2022

New therapies for AIRDs can reduce the harmful side-effects caused by conventional treatments

New therapies for autoimmune rheumatic diseases (AIRDs) that are designed to better regulate lipid (fat) metabolism, could significantly reduce the harmful side-effects caused by conventional treatments, finds a new large-scale review led by UCL researchers.

19 Jan 2022

Study finds a subset of vascular macrophages to be powerful ally in the fight against atherosclerosis

A new study reveals the existence of a powerful ally in the fight against cardiovascular disease, a protective subset of vascular macrophages expressing the C-type lectin receptor CLEC4A2, a molecule which fosters "good" macrophage behavior within the vessel wall.

11 Jan 2022

Researchers identify factors at midlife linked with 10-year declines in women's physical health

Among 55-year-old women, factors such as higher body mass index, smoking, osteoarthritis, depressive symptoms and more were associated with clinically important declines in physical health 10 years later.

9 Jan 2022

Study examines if antidepressants can benefit patients with osteoarthritis

A clinical trial published in Arthritis & Rheumatology recently examined whether duloxetine, a medication that is prescribed to treat depression and may also reduce chronic pain, can benefit patients with hip or knee osteoarthritis.

6 Jan 2022

Scientists unravel how LPS prevents or promotes development of allergic disease

Immunologists have long been baffled by LPS, the bacterial lipopolysaccharide that helps form the cell walls of Gram-negative bacteria.

5 Jan 2022

Scientists find that having one kind of autoimmune disease can lead to another

Researchers at the University of Colorado Anschutz Medical Campus have discovered that having one kind of autoimmune disease can lead to another.

4 Jan 2022

Insight into immune cell communication may pave the way for new cancer vaccines

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences.

9 Dec 2021

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Despite clear directives outlined in the updated guidelines published by the American College of Rheumatology/National Psoriasis Foundation (ACR/NPF) in 2018, there is limited data regarding medication use in real-world clinical practice and patient medication preferences for the treatment of psoriatic arthritis (PsA).

9 Nov 2021

Risk factors for "long-haul" COVID in people with rheumatic diseases identified

A new study by researchers at Hospital for Special Surgery (HSS) in New York City demonstrates over half of patients with rheumatic diseases who contracted COVID-19 during the pandemic and completed a COVID-19 survey, experienced so-called "long-haul" COVID, or prolonged symptoms of the infection, including loss of taste or smell, muscle aches and difficulty concentrating, for one month or longer.

7 Nov 2021

Global effort focuses on developing better methods to quantify joint damage in rheumatoid arthritis patients

Crowdsourcing has become an increasingly popular way to develop machine learning algorithms to address many clinical problems in a variety of illnesses.

7 Nov 2021

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

7 Nov 2021

Cycling JAK inhibitors can be effective for treating people with difficult-to-treat rheumatoid arthritis

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that people with difficult-to-treat rheumatoid arthritis who do not have success with one Janus kinase inhibitor (JAK inhibitor) can achieve success either cycling to other JAKi medications or switching to a biologic drug.

2 Nov 2021

RA patients taking glucocorticoids or B-cell therapies may have worse COVID-19 vaccine response

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that people with chronic inflammatory diseases, such as rheumatoid arthritis (RA), who take immunosuppressive therapy appear to have an impaired immunity response to SARS-CoV-2, the coronavirus that causes COVID-19, vaccines. Patients currently on glucocorticoids or B-cell depleting therapy appear to have an even more severely impeded vaccine response.

2 Nov 2021

Study finds persistent racial gaps in renal complications for children with juvenile lupus

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that while hospitalized children with juvenile lupus have fewer adverse kidney outcomes overall, significant racial gaps for developing these complications persist and do not seem to be narrowing.

2 Nov 2021

Rheumatology News and Research

Further Reading

Study characterizes brain changes in adolescents affected by juvenile fibromyalgia

Use of immunosuppressants for inflammatory rheumatic diseases and the associated risk of severe COVID-19

Colchicine holds promise to reduce the risk of severe COVID-19

Study investigates how vitamin D or omega fatty acids may affect rates of autoimmune diseases

Immunosuppressed patients can benefit from COVID-19 booster vaccination, study shows

New, more accurate tool to measure the progress of lupus in patients

New therapies for AIRDs can reduce the harmful side-effects caused by conventional treatments

Study finds a subset of vascular macrophages to be powerful ally in the fight against atherosclerosis

Researchers identify factors at midlife linked with 10-year declines in women's physical health

Study examines if antidepressants can benefit patients with osteoarthritis

Scientists unravel how LPS prevents or promotes development of allergic disease

Scientists find that having one kind of autoimmune disease can lead to another

Insight into immune cell communication may pave the way for new cancer vaccines

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Risk factors for "long-haul" COVID in people with rheumatic diseases identified

Global effort focuses on developing better methods to quantify joint damage in rheumatoid arthritis patients

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

Cycling JAK inhibitors can be effective for treating people with difficult-to-treat rheumatoid arthritis

RA patients taking glucocorticoids or B-cell therapies may have worse COVID-19 vaccine response

Study finds persistent racial gaps in renal complications for children with juvenile lupus

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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