Tau Protein News and Research

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Tau proteins are microtubule-associated proteins found in neurons in the brain.

Why some patients with brain markers for Alzheimer's never develop the condition

Scientists have discovered the reason why patients who show brain markers for Alzheimer's never develop the condition.

17 Aug 2018

Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases

There is new hope for the treatment of Alzheimer’s and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Novel discovery offers hope for treatment of Alzheimer's and other neurological diseases

There is new hope for the treatment of Alzheimer's and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.

10 Aug 2018

Alzheimer’s-in-a-dish model made better with microfluidic system

Researchers from Massachusetts have used a microfluidic device to incorporate neuroinflammation into the Alzheimer's-in-a-dish model for drug discovery.

31 Jul 2018

Reduced plasmalogen level may increase risk of Alzheimer's disease, shows study

Reduced levels of plasmalogens - a class of lipids created in the liver that are integral to cell membranes in the brain - are associated with an increased risk of Alzheimer's Disease, according to new research presented this week at the Alzheimer's Association International Conference 2018 by Mitchel A. Kling, MD, an associate professor of Psychiatry in the Perelman School of Medicine at the University of Pennsylvania and the Veterans Affairs Medical Center.

25 Jul 2018

Scientists find abnormal gene copying in fruit fly models of tauopathies

It sounds like science fiction: Nefarious genes clone themselves and settle their rogue copies in distant outposts of the galaxy (namely, our DNA), causing disease.

24 Jul 2018

Scientists discover ‘Big Bang’ of Alzheimer's disease

Scientists have discovered a "Big Bang" of Alzheimer's disease - the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain.

11 Jul 2018

Tau protein allows microtubules to grow and remain dynamic, shows study

A new study by researchers from Drexel University College of Medicine reverses the popular scientific dogma that the protein tau stabilizes microtubules within brain cells.

30 Jun 2018

Tau mutations may serve as novel risk factor for cancer

Mutations to the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer, according to results published in Cancer Research, a journal of the American Association for Cancer Research.

24 May 2018

New study reveals the extent of brain damage due to elevated homocysteine

The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism.

17 May 2018

ALS and frontotemporal dementia share genetic connections

Nearly half of all patients with amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder, develop cognitive problems that affect memory and thinking.

9 Apr 2018

InSysBio evaluates tau protein phosphorylation related targets for treatment of AD

InSysBio continues to investigate the mechanisms underlying Alzheimer's disease using the quantitative systems pharmacology modeling approach. The part of QSP model describing tau protein was published in the PLOS ONE journal. This is one of more than dozen InSysBio publications in AD area during last seven years.

28 Feb 2018

Amyloid protein may be transmitted through neurosurgical instruments, study suggests

Amyloid beta pathology - protein deposits in the brain - might have been transmitted by contaminated neurosurgical instruments, suggests a new UCL-led study.

15 Feb 2018

Low dose alcohol everyday might actually "clean" the brain

A new study in mice has suggests that a couple of glasses of wine may actually “clean” the brain and not only clear the mind at the end of a long day. The study was published in the latest issue of the journal Scientific Reports.

5 Feb 2018

Chronic traumatic encephalopathy may start early even without signs of concussions

The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic encephalopathy, and the relationships between these disorders, are poorly understood.

18 Jan 2018

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

5 Dec 2017

Alzheimer's Tau protein interacts with cell membranes and forms toxic complexes

The brains of patients with Alzheimer's disease contain characteristic tangles inside neurons. These tangles are formed when a protein called Tau aggregates into twisted fibrils. As a result, the neurons' transport systems disintegrate, essential nutrients can't move through, and the cells begin to die, affecting the brain's functions and giving rise to the disease's symptoms.

22 Nov 2017

Researchers uncover mechanism that contributes to patterns of degeneration in AD

Alzheimer's disease (AD) is known to cause memory loss and cognitive decline, but other functions of the brain can remain intact.

17 Nov 2017

Shear shock waves may explain why some head knocks cause more harm than others

Veteran sailors know that rogue waves can rise suddenly in mid-ocean to capsize even the largest vessels. Now it appears that a similar phenomenon called shear shock wave occurs in the concussed brain. It may help explain why some head knocks cause so much more harm than others.

1 Nov 2017

New tool helps researchers to identify and detect various sub-groups of Alzheimer’s disease

Alzheimer's disease can lead to several widely divergent symptoms and, so far, its various expressions have mainly been observed through the behaviour and actions of patients.

31 Aug 2017