Clinical Trial News and Research

RSS

UC San Diego Health first to offer new injectable medication to patients with hereditary transthyretin amyloidosis

UC San Diego Health is first in the nation to offer a new injectable medication to patients with nerve damage caused by hereditary transthyretin amyloidosis, a rare disease that can be fatal without management.

18 Aug 2022

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

A team of University of Michigan researchers is developing a new anti-cancer drug that is absorbed through the gut's lymphatic system rather than blood vessels, potentially outmaneuvering the molecular signaling pathways that lead to drug resistance while increasing cancer-fighting ability and reducing side effects.

17 Aug 2022

Expert panel identifies critical challenges in recruiting study participants

Unless cures are found, Alzheimer's dementia is projected to affect nearly 13 million Americans by 2050 - overwhelming families, caregivers and our healthcare system. Yet only one new therapeutic, aducanumab, has come to market in the past 20 years, and therapeutic progress remains hampered for several reasons: recruiting study participants in clinical trials for Alzheimer's is more challenging than other disease areas, the trials take longer to complete and they are more costly.

17 Aug 2022

LSHTM expert comment: UK's MHRA approves bivalent COVID-19 vaccine

The UK's Medicines and Healthcare products Regulatory Agency (MHRA) has approved a booster vaccine made by Moderna which targets two COVID-19 variants, known as a bivalent vaccine. Following clinical trial data that showed it triggers a strong immune response against both strains, the vaccine was found to meet the UK regulator's standards for safety, quality and effectiveness. Vaccine expert, Professor Beate Kampmann reacts to this announcement.

16 Aug 2022

Research analyzes the impact of virtual tours on older adults experiencing social isolation

Scientists have long known that social isolation is associated with a number of health problems, including increased risks for stroke and heart disease, as well as mental decline and even premature death. The risks are especially acute for older adults, who are more likely to be socially isolated and lonely. The coronavirus pandemic only exacerbated the problem due to the need for social distancing, particularly to protect the health of the world's elderly population.

16 Aug 2022

Three genetic mutations seen in individuals with KCNMA1-linked channelopathy successfully mirrored in mice

Three genetic alterations associated with a rare seizure and a movement disorder primarily found in children were successfully mirrored in mice and their symptoms treated, in a new study from a University of Maryland School of Medicine researcher, Andrea Meredith, PhD, Professor of Physiology and her collaborators.

15 Aug 2022

MHRA approves first bivalent COVID-19 booster vaccine

An updated version of the COVID-19 vaccine made by Moderna that targets two coronavirus variants (known as a "bivalent" vaccine) has today been approved for adult booster doses by the Medicines and Healthcare products Regulatory Agency (MHRA) after it was found to meet the UK regulator's standards of safety, quality and effectiveness.

15 Aug 2022

Do pre-existing antibodies alter the development of memory B cells in response to SARS-CoV-2 mRNA vaccination in humans?

Researchers explored how passive administration of monoclonal antibodies impact the development of immunological memory in response to COVID-19 vaccination.

15 Aug 2022

Manageable amounts of daily physical activity could be the most beneficial approach, research shows

So… should I exercise a little bit every day, or exercise for longer once a week?

15 Aug 2022

People with blood-related cancers more likely to experience COVID breakthrough infections

Individuals with blood-related cancers are more likely to experience a COVID-19 infection even after being vaccinated, a University of Kansas Cancer Center study has found.

12 Aug 2022

Auckland scientists develop novel mobile-phone-based therapy for tinnitus

After 20 years searching for a cure for tinnitus, researchers at the University of Auckland are excited by 'encouraging results' from a clinical trial of a mobile-phone-based therapy. The study randomized 61 patients to one of two treatments, the prototype of the new 'digital polytherapeutic' or a popular self-help app producing white noise.

12 Aug 2022

Gene discovery could help develop new tools to prevent strokes and heart attacks

Heart attacks and strokes are a leading cause of death in the United States, but scientists are still working to understand one of their primary triggers.

11 Aug 2022

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

A new study reviews recent advancements made in the development of RSV immunoprophylactic measures.

11 Aug 2022

New gel-based cartilage substitute is stronger and more durable than the real thing

Over-the-counter pain relievers, physical therapy, steroid injections -- some people have tried it all and are still dealing with knee pain.

11 Aug 2022

Leaving small, asymptomatic kidney stones behind increases patient's risk of relapse

When surgeons remove patients' kidney stones, they typically leave behind small stones that appear not to be causing problems.

11 Aug 2022

SARS-CoV-2 receptor-binding domain-based protein subunit vaccine shows promise against multiple SARS-CoV-2 variants

Researchers described a novel protein subunit vaccine comprising the receptor-binding domain (RBD) of ancestral SARS-CoV-2 spike (S) protein, dimerized with an immunoglobulin (Ig)G1-fraction, crystallizable (Fc) domain.

11 Aug 2022

Azelastine nasal spray could decrease SARS-CoV-2 load

A new study illustrated that early azelastine nasal spray therapy might lower the SARS-CoV-2 load among virus-infected patients.

11 Aug 2022

Repurposed drug shows promise as potential new treatment for motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.

11 Aug 2022

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a National Institutes of Health clinical trial has found.

10 Aug 2022

Study uncovers new prognostic marker for multiple sclerosis severity

It is essential to assess the severity of multiple sclerosis (MS) in order to choose appropriate therapeutic measures, but this cannot be reliably done using existing methods.

10 Aug 2022

Clinical Trial News and Research

UC San Diego Health first to offer new injectable medication to patients with hereditary transthyretin amyloidosis

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

Expert panel identifies critical challenges in recruiting study participants

LSHTM expert comment: UK's MHRA approves bivalent COVID-19 vaccine

Research analyzes the impact of virtual tours on older adults experiencing social isolation

Three genetic mutations seen in individuals with KCNMA1-linked channelopathy successfully mirrored in mice

MHRA approves first bivalent COVID-19 booster vaccine

Do pre-existing antibodies alter the development of memory B cells in response to SARS-CoV-2 mRNA vaccination in humans?

Manageable amounts of daily physical activity could be the most beneficial approach, research shows

People with blood-related cancers more likely to experience COVID breakthrough infections

Auckland scientists develop novel mobile-phone-based therapy for tinnitus

Gene discovery could help develop new tools to prevent strokes and heart attacks

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

New gel-based cartilage substitute is stronger and more durable than the real thing

Leaving small, asymptomatic kidney stones behind increases patient's risk of relapse

SARS-CoV-2 receptor-binding domain-based protein subunit vaccine shows promise against multiple SARS-CoV-2 variants

Azelastine nasal spray could decrease SARS-CoV-2 load

Repurposed drug shows promise as potential new treatment for motor neuron disease

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

Study uncovers new prognostic marker for multiple sclerosis severity

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer