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Experts identify key measures to reduce alcohol consumption in Germany

Research paper discusses the high levels of alcohol consumption in Germany and proposes enhancing alcohol health literacy as a way to reduce consumption. The aim of the study is to identify and prioritize measures to improve alcohol health literacy.

15 May 2023

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina.

15 May 2023

UArizona Health Sciences researchers seek to improve opioid therapy while decreasing its side effects

University of Arizona Health Sciences researchers are taking the foot off the brake in their quest to improve opioid therapy while decreasing its side effects.

15 May 2023

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

Advanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor.

15 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

Creating the Lab of the Future; What does it entail?

As part of our SLAS US 2023 coverage, we speak to Luigi Da Via, Team Leader in Analytical Development at GSK, about the lab of the future, and what it may look like.

From Society for Laboratory Automation and Screening (SLAS) 15 May 2023

Drug combination can prolong survival and improve quality of life in patients with advanced lung cancer

A recent clinical trial showed that the drug combination of cemiplimab plus platinum chemotherapy can prolong survival in patients with advanced lung cancer when compared with placebo plus platinum chemotherapy. Now an analysis published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, indicates that cemiplimab plus platinum chemotherapy also affects quality of life compared to chemotherapy alone.

13 May 2023

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with head and neck cancer (HNC).

12 May 2023

Study identifies extremely potent monoclonal antibodies that neutralized multiple sarbecoviruses

Researchers longitudinally isolated immensely potent monoclonal antibodies from macaques vaccinated with COVID-19.

12 May 2023

Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

New approach could help inform future lens design for treating myopia

Researchers have developed new instruments for rigorously quantifying and comparing the light-focusing properties of specialized eyeglass lenses that are used to slow the progression of myopia, or nearsightedness.

11 May 2023

Is medical cannabis treatment associated with improvements in health-related quality of life?

Researchers investigated whether cannabis treatment could improve the health-associated quality of life.

11 May 2023

Can cognitive behavioral therapy target severe fatigue following COVID-19?

Researchers examined the efficacy of cognitive behavioral therapy (CBT) for severe fatigue after COVID-19.

11 May 2023

New tool launched to make ESMO Clinical Practice Guidelines easier to use in routine clinical practice

ESMO, the leading professional organization for medical oncology, today announced the launch of a new tool designed to make the renowned ESMO Clinical Practice Guidelines (CPGs) easier to use in oncologists' routine clinical practice and support optimal decision-making in a rapidly evolving medical field.

10 May 2023

Study sheds light on a possible pharmacological approach to treat cardiac arrhythmias

Scientists at Simon Fraser University (SFU) and the Lankenau Institute for Medical Research (LIMR) near Philadelphia have found that a drug discovered at SFU and patented several years ago may have potential lifesaving results in the treatment of conditions leading to sudden cardiac death.

10 May 2023

Cardiovascular risk reduction in type 2 diabetes: Study urges better use of life-saving therapies

Researchers explore the efficacy of current approaches to reduce the risk of cardiovascular events in patients with type 2 diabetes.

10 May 2023

Nirmatrelvir/ritonavir reduces the risk of COVID-19-associated hospitalization

Researchers assess whether nirmatrelvir/ritonavir treatment reduced the risk of COVID-19-related hospitalization.

10 May 2023

Concomitant tuberculosis disease significantly impacts HIV immune responses in people with HIV

New research from Boston Medical Center found that people living with HIV that have had pulmonary tuberculosis had broader and more potent HIV antibody responses and differences in HIV sequences predicted to be antibody resistant as compared to those without suspected or documented tuberculosis.

9 May 2023

Vitamin D intake could reduce cancer mortality

Vitamin D intake could reduce cancer mortality in the population by twelve percent - provided the vitamin is taken daily.

9 May 2023

Efficacy News and Research

Experts identify key measures to reduce alcohol consumption in Germany

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

UArizona Health Sciences researchers seek to improve opioid therapy while decreasing its side effects

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Creating the Lab of the Future; What does it entail?

Drug combination can prolong survival and improve quality of life in patients with advanced lung cancer

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

Study identifies extremely potent monoclonal antibodies that neutralized multiple sarbecoviruses

Targeting the hemoglobin problem in sickle cell disease using a new drug

New approach could help inform future lens design for treating myopia

Is medical cannabis treatment associated with improvements in health-related quality of life?

Can cognitive behavioral therapy target severe fatigue following COVID-19?

New tool launched to make ESMO Clinical Practice Guidelines easier to use in routine clinical practice

Study sheds light on a possible pharmacological approach to treat cardiac arrhythmias

Cardiovascular risk reduction in type 2 diabetes: Study urges better use of life-saving therapies

Nirmatrelvir/ritonavir reduces the risk of COVID-19-associated hospitalization

Concomitant tuberculosis disease significantly impacts HIV immune responses in people with HIV

Vitamin D intake could reduce cancer mortality

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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