Immune System News and Research

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Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

Patients taking efgartigimod, a drug being studied for use to treat chronic primary immune thrombocytopenia (ITP), exhibited a significantly greater improvement in platelet counts which are essential to clotting and stopping bleeding, compared to those taking a placebo, according to results reported from the ADVANCE IV clinical trial, which was conducted globally, including at Georgetown University Medical Center.

12 Dec 2022

How vaping impacts alveolar macrophage lipid content

The use of e-cigs increases the risk of acute respiratory syndrome.

11 Dec 2022

An epigenetic modification improves the defense against infections, research shows

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens.

9 Dec 2022

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma.

9 Dec 2022

UH researchers investigate how traumatic experiences affect mental and physical health of migrants

In a first of its kind study, University of Houston psychology researchers are investigating how the trauma experienced by migrants before and during the journey to the United States affects their mental and physical health.

8 Dec 2022

Multi-stage HIV vaccine regimen shows promising results in Phase 1 clinical trial

The George Washington University Vaccine Research Unit in partnership with Scripps Research, IAVI, Fred Hutchinson Cancer Center (FHCC) and the National Institutes of Health, National Institute of Allergy and Infectious Diseases Vaccine Research Center published the results of their Phase 1 Clinical Trial in Science.

8 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Study explores the risk of new-onset diabetes mellitus following SARS-CoV-2 infections

Researchers evaluated individuals who had SARS-CoV-2 infections and were diagnosed with diabetes mellitus within six months of the onset of COVID-19 to understand the temporal relationship between SARS-CoV-2 infections and diabetes mellitus.

8 Dec 2022

Cancer immunotherapies can become more potent depending on the time of day

Scientists from the UNIGE and LMU show that the anti-tumor activity of the immune system - and the effectiveness of cancer immunotherapies - depends on the time of day.

7 Dec 2022

Air pollution-triggered immune surveillance deficits in the lungs increase the risk of respiratory diseases with aging

Researchers highlighted the significance of air quality in preserving immune health over the human lifespan, especially lung-related immunity, owing to the lungs' continuous exposure to the environment.

7 Dec 2022

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Nearly three years into the pandemic, many of us now carry antibodies against the virus - due to an infection or two, a few doses of mRNA vaccine, or a round of monoclonal-antibody treatment.

6 Dec 2022

Research extends the powerful tool of immunotherapy to autoimmune diseases

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

6 Dec 2022

Study suggests new anti-KRAS drug as a strong candidate for pancreatic cancer clinical trials

A small molecule inhibitor that attacks the difficult to target, cancer-causing gene mutation KRAS, found in nearly 30 percent of all human tumors, successfully shrunk tumors or stopped cancer growth in preclinical models of pancreatic cancer, researchers from Penn Medicine's Abramson Cancer Center showed, suggesting the drug is a strong candidate for clinical trials.

6 Dec 2022

The critical role of flow cytometry in CAR+ T-Cell trials

In this interview, Ryan Muise talks to AZoNetwork about the added value of using flow cytometry in CAR T-Cell clinical trials.

From Cerba Research 6 Dec 2022

Perinatal exposure to inorganic nanoparticles may make babies more vulnerable to food allergies

Nanotechnologies have revolutionized food technology with changes to food production, manufacture, and processing that are intended to make our food safer and healthier.

5 Dec 2022

How two structurally different lemon pectins modulate the gut microbiota

A diet containing fruits and vegetables contains pectins (plant polysaccharides). Pectin cannot be metabolized by mammalian cells in the gastrointestinal tract but is fermented by the gut microbiota in the colon, where short-chain fatty acids (SCFAs) are released. Previous studies have examined pectin's prebiotic properties.

4 Dec 2022

AI could make doctors’ work simpler, faster, and more precise

One in nine women in the developed world will be diagnosed with breast cancer at some point in her life. The prevalence of breast cancer is increasing, an effect caused in part by the modern lifestyle and increased lifespans.

2 Dec 2022

Sharp increase in B cell population can prevent intestinal healing

B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, preventing the tissue from healing.

2 Dec 2022

Women with postpartum mood disorders may be suffering from irregular immune system responses

Women with prolonged mental health problems up to three years after childbirth may be suffering from irregular immune system responses, according to new research by Cedars-Sinai investigators.

2 Dec 2022

Vaccination against pertussis in pregnancy and outstanding scientific questions

A recent paper published in Vaccines summarized the data presented and the discussions in the meeting regarding pertussis vaccination in pregnancy (ViP).

2 Dec 2022

Immune System News and Research

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

How vaping impacts alveolar macrophage lipid content

An epigenetic modification improves the defense against infections, research shows

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

UH researchers investigate how traumatic experiences affect mental and physical health of migrants

Multi-stage HIV vaccine regimen shows promising results in Phase 1 clinical trial

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

Study explores the risk of new-onset diabetes mellitus following SARS-CoV-2 infections

Cancer immunotherapies can become more potent depending on the time of day

Air pollution-triggered immune surveillance deficits in the lungs increase the risk of respiratory diseases with aging

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Research extends the powerful tool of immunotherapy to autoimmune diseases

Study suggests new anti-KRAS drug as a strong candidate for pancreatic cancer clinical trials

The critical role of flow cytometry in CAR+ T-Cell trials

Perinatal exposure to inorganic nanoparticles may make babies more vulnerable to food allergies

How two structurally different lemon pectins modulate the gut microbiota

AI could make doctors’ work simpler, faster, and more precise

Sharp increase in B cell population can prevent intestinal healing

Women with postpartum mood disorders may be suffering from irregular immune system responses

Vaccination against pertussis in pregnancy and outstanding scientific questions

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