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OPKO Health completes patient enrollment in first phase 3 trial of Rayaldy for SHPT treatment

OPKO Health, Inc., has completed patient recruitment in the first phase 3 trial of Rayaldy to treat patients with secondary hyperparathyroidism, stage 3 or 4 chronic kidney disease and vitamin D insufficiency.

16 Nov 2013

Small molecule compound shows significant success in controlling polyomaviruses

A team of scientists reports that a small molecule compound showed significant success in controlling the infectivity and spread of three polyomaviruses in human cell cultures. To date there has been no medicine approved to treat such viruses, which prey on transplant recipients, people with HIV, and others whose immune systems have been weakened.

15 Nov 2013

Internal body clock may contribute to morning peak in heart attacks and ischemic strokes

Cardiovascular disease is the number one cause of death in both men and women, and most adverse cardiovascular events tend to happen in the morning. In new findings published in the November issue of Blood, researchers from Brigham and Women's Hospital (BWH) and Oregon Health & Science University have discovered that the internal body clock may contribute to the morning peak in heart attacks and ischemic strokes.

13 Nov 2013

Tailored doses of pre-transplant drug therapy in Glaucomatous patients boosts survival rates to over 90%

Chronic Granulomatous Disease is a rare immune deficiency that seriously compromises organ function and is life-threatening, with 20-30 per cent of patients dying within the first two decades of life.

13 Nov 2013

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

FibroGen, Inc. (FibroGen), today announced that data from a China-based Phase 2 study of roxadustat (FG-4592), a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD), were presented in an oral session at the 2013 American Society of Nephrology (ASN) Kidney Week in Atlanta, Georgia.

13 Nov 2013

Results announced for Phase 3B/4 study of RAPAMUNE in kidney transplant patients

Pfizer Inc. (NYSE:PFE) announced today top-line results from a Phase 3B/4 study of RAPAMUNE® (sirolimus) evaluating kidney transplant patients who transitioned from tacrolimus-based therapy (TAC) to RAPAMUNE® 3 to 5 months after transplant.

12 Nov 2013

Livers from donors with pre-hospital cardiac arrest considered for transplant

Researchers from the U.K. suggest that using organs from donors after circulatory death (DCD) who also suffered a previous cardiac arrest out of the hospital environment could expand the pool of available livers for transplant.

11 Nov 2013

Generating an alternative to IVIG therapy: an interview with Professor Richard Pleass, LSTM

IVIG is a hugely successful biological with FDA approval for treating idiopathic thrombocytopenic purpura (ITP), Kawasaki disease, Guillain-Barré syndrome, Graves ophthalmopathy and numerous polyneuropathies.

11 Nov 2013

Cycling champion Cadel Evans takes part in cutting edge cardiopulmonary research

As the first Australian to win the Tour de France, cycling champion Cadel Evans has already pedalled his way into our hearts. Now he is taking part in world-leading cardiopulmonary research – by pedalling inside an MRI scanner.

11 Nov 2013

Risk of dangerous bloodstream infections can be reduced in newborns with central venous catheters

A new study led by Johns Hopkins Children's Center investigators shows that clinicians can reduce the risk of dangerous bloodstream infections in newborns with central venous catheters by ending use of the device as soon as possible, rather than waiting for signs of infection.

11 Nov 2013

Patients' quality of life negatively affected by perceived discrimination, mistrust in health care

Perceived discrimination and mistrust in health care can negatively affect patients' quality of life, according to a study that will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

11 Nov 2013

Treatment with rheumatoid arthritis drug saved transplanted kidney and achieved remission

A drug approved for the treatment of rheumatoid arthritis may also turn out to be the first targeted therapy for one of the most common forms of kidney disease, a condition that almost inevitably leads to kidney failure.

11 Nov 2013

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

A team of scientists that includes Saint Louis University researchers has identified a new way to intervene in the molecular and cellular cascade that causes fibrosis - a condition where the body's natural process of forming scars for wound healing goes into overdrive and causes diseases.

11 Nov 2013

Adequate vitamin D levels vital for maintaining the health of kidney transplant recipients

Adequate vitamin D levels are important for maintaining kidney transplant recipients' health, according to a study that will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

10 Nov 2013

Tissue scarring may help develop new treatments for patients with damaged organs

Patients with damaged organs could be helped by new treatments after scientists have discovered how tissues scar.

10 Nov 2013

New zebrafish technique finds potential treatments for multiple diseases

Skeletal muscle has proved to be very difficult to grow in patients with muscular dystrophy and other disorders that degrade and weaken muscle. Researchers at Boston Children's Hospital's Stem Cell Program now report boosting muscle mass and reversing disease in a mouse model of Duchenne muscular dystrophy, using a "cocktail" of three compounds identified through a new rapid culture system. Adding the same compounds to stem cells derived from patients' skin cells, they then successfully grew human muscle cells in a dish.

8 Nov 2013

Northwestern Medicine receives $12 million to continue organ transplant research with stem cells

An innovative Northwestern Medicine- research program investigating if stem cells may be the key to allowing organ transplant patients to stop taking immunosuppressive drugs has received $12 million in research funding. The grant will allow researchers to finish Phase II of the clinical trials and begin Phase III.

8 Nov 2013

Life-saving bone marrow transplants may also cure peanut allergies

Not only can bone marrow transplants be life-saving for children with acute lymphocytic leukemia, they may also cure peanut allergies. According to research presented during the American College of Allergy, Asthma and Immunology's Annual Scientific Meeting, a 10-year-old boy no longer had a peanut allergy after undergoing a bone marrow transplant.

8 Nov 2013

Michael Kors gifts $3M to Weill Cornell Medical College to support immunology research

Award-winning fashion designer Michael Kors has dedicated his career to designing luxury American sportswear. Now, with a $3 million gift to Weill Cornell Medical College, one of America's most recognized faces in fashion is seeking to significantly help advance human health.

8 Nov 2013

UC researchers receive FDA grant to study generic tacrolimus in high-risk transplant patients

Transplant researchers at the University of Cincinnati have received a grant from the U.S. Food and Drug Administration to study the safety and efficacy of a generic immunosuppressive drug in high-risk transplant patients.

7 Nov 2013

Transplant News and Research

OPKO Health completes patient enrollment in first phase 3 trial of Rayaldy for SHPT treatment

Small molecule compound shows significant success in controlling polyomaviruses

Internal body clock may contribute to morning peak in heart attacks and ischemic strokes

Tailored doses of pre-transplant drug therapy in Glaucomatous patients boosts survival rates to over 90%

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

Results announced for Phase 3B/4 study of RAPAMUNE in kidney transplant patients

Livers from donors with pre-hospital cardiac arrest considered for transplant

Generating an alternative to IVIG therapy: an interview with Professor Richard Pleass, LSTM

Cycling champion Cadel Evans takes part in cutting edge cardiopulmonary research

Risk of dangerous bloodstream infections can be reduced in newborns with central venous catheters

Patients' quality of life negatively affected by perceived discrimination, mistrust in health care

Treatment with rheumatoid arthritis drug saved transplanted kidney and achieved remission

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

Adequate vitamin D levels vital for maintaining the health of kidney transplant recipients

Tissue scarring may help develop new treatments for patients with damaged organs

New zebrafish technique finds potential treatments for multiple diseases

Northwestern Medicine receives $12 million to continue organ transplant research with stem cells

Life-saving bone marrow transplants may also cure peanut allergies

Michael Kors gifts $3M to Weill Cornell Medical College to support immunology research

UC researchers receive FDA grant to study generic tacrolimus in high-risk transplant patients

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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