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Study explores rapid SARS-CoV-2 genome sequencing to help reduce hospital-acquired COVID-19 infections

In a new study, researchers examined whether SARS-CoV-2 whole-genome sequencing could be routinely used for infection prevention and control in hospitals.

15 Feb 2022

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

A new study published demonstrated the in vitro potencies of RDV and GS-441524 through PRA, and nucleoprotein ELISA against SARS-CoV-2 and other VOC/VOIs isolates with specific substitutions in Nsp12.

15 Feb 2022

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Single-cell RNA sequencing, or "scRNA-seq" for short, is a technique that allows scientists to study the expression of genes in an individual cell within a mixed population – which is virtually how all cells exist in the body's tissues.

15 Feb 2022

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

In a recent study posted to the bioRxiv* preprint server, a team of researchers from Washington, United States, investigated the transmission of viral genetic diversity during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) superspreading outbreak among the crew members on a fishing boat.

14 Feb 2022

First survey on Omicron BA.2 in France

In a recent study posted to the medRxiv* preprint server, researchers described the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 21L/BA.2 Omicron variant in south-eastern France.

14 Feb 2022

RNA capping mechanism of SARS-CoV-2 unveiled

In a recent study posted to the bioRxiv* preprint server, researchers elucidated the mechanism of ribonucleic acid (RNA) capping in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

14 Feb 2022

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Researchers reported the development and validation of a two-reaction multiplex reverse transcription-quantitative polymerase chain reaction genotyping strategy that distinguishes SARS-CoV-2 variants of concern.

14 Feb 2022

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.

14 Feb 2022

Study shows expression of viral proteases may be used to quantitate SARS-CoV-2 infected cells

A new study describes a new method to quantify SARS-CoV-2 infection, which is much simpler and faster compared to existing methods.

14 Feb 2022

First unbiased proteome scale study expands the number of known transcriptional activators

Also known as transcriptional activators for their ability to induce transcription of genes into RNA messages, these proteins are essential for the cells to function properly. Yet little is known about these proteins, and it wasn't clear how many activators there might be in human cells – until now.

11 Feb 2022

Drugs used to increase insulin signaling may be effective therapeutic strategy for autism

Drugs to increase insulin signaling may be effective for treating autism say Lancaster University researchers, who have discovered how a genetic change impacts on insulin signaling and glucose metabolism in the brain.

10 Feb 2022

Artificial intelligence uses facial features to better diagnose rare genetic diseases

Rare genetic diseases can sometimes be recognized through facial features, such as characteristically shaped brows, nose or cheeks.

10 Feb 2022

Scientists introduce a genetic mutation to provide protection against Alzheimer's disease

Researchers from the Université Laval Faculty of Medicine and CHU de Québec–Université Laval Research Centre have successfully edited the genome of human cells grown in vitro to introduce a mutation providing protection against Alzheimer's disease.

10 Feb 2022

Spillover of SARS-CoV-2 Omicron variant infection in white-tailed deer in New York

Researchers detected evidence for SARS-CoV-2 Omicron variant exposure in the white-tailed deer population inhabiting Staten Island in New York.

10 Feb 2022

Clinical severity of COVID-19 caused by SARS-CoV-2 variants and the effectiveness of mRNA vaccines against them

A recent study examined the clinical severity of the SARS-CoV-2 Alpha, Delta, and Omicron VOCs and compared vaccine effectiveness against each VOC.

10 Feb 2022

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

In two recent studies, researchers at Washington University School of Medicine in St. Louis found evidence that the omicron variant of the virus that causes COVID-19 causes less severe disease than previous variants — at least in rodents — but that many antibody-based therapies may not be effective against it.

10 Feb 2022

Genome News and Research

Study explores rapid SARS-CoV-2 genome sequencing to help reduce hospital-acquired COVID-19 infections

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

First survey on Omicron BA.2 in France

RNA capping mechanism of SARS-CoV-2 unveiled

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Study shows expression of viral proteases may be used to quantitate SARS-CoV-2 infected cells

First unbiased proteome scale study expands the number of known transcriptional activators

Drugs used to increase insulin signaling may be effective therapeutic strategy for autism

Artificial intelligence uses facial features to better diagnose rare genetic diseases

Scientists introduce a genetic mutation to provide protection against Alzheimer's disease

Spillover of SARS-CoV-2 Omicron variant infection in white-tailed deer in New York

Clinical severity of COVID-19 caused by SARS-CoV-2 variants and the effectiveness of mRNA vaccines against them

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

Machine learning highly effective at identifying SARS-CoV-2 variants

Researchers identify and characterize a previously unrecognized key player in cancer evolution

Super-resolution imaging of the human coronavirus genome during infection

Study explores wastewater surveillance of US military installations to mitigate the spread of SARS-CoV-2

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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