Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

PET/CT may improve differentiation of PTSD from MTBI

Hybrid imaging with positron emission tomography and computed tomography (PET/CT) in the pituitary region of the brain is a promising tool for differentiating military veterans with post-traumatic stress disorder (PTSD) from those with mild traumatic brain injury (MTBI), according to a new study presented at the annual meeting of the Radiological Society of North America (RSNA).

1 Dec 2014

DFG to establish new Collaborative Research Centres

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) will establish eight new Collaborative Research Centres (CRCs).

29 Nov 2014

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

A promising experimental immunotherapy drug works best in patients whose immune defenses initially rally to attack the cancer but then are stymied by a molecular brake that shuts down the response, according to a new study led by researchers at Dana-Farber Cancer Institute and the Yale University School of Medicine.

28 Nov 2014

Immune-suppressing protein may predict how patients respond to treatment

The presence of an immune-suppressing protein in non-cancerous immune cells may predict how patients with different types of cancer respond to treatment, a multi-center phase I study using an investigational immune therapy drug has found.

27 Nov 2014

External artificial pancreas improves glucose control, reduces hypoglycemia risk

The world's first clinical trial comparing three alternative treatments for type 1 diabetes was conducted in Montréal by researchers at the IRCM and the University of Montreal, led by endocrinologist Dr. Rémi Rabasa-Lhoret.

27 Nov 2014

Scientists make breakthrough in developing new treatment for advanced bladder cancer

Scientists from Queen Mary University of London have made a breakthrough in developing a new therapy for advanced bladder cancer - for which there have been no major treatment advances in the past 30 years.

26 Nov 2014

Perc NGage® and Perc NCompass® nitinol stone extractors launched by Cook Medical

Urologists now have new options for stone extraction devices when performing percutaneous nephrolithotomy (PCNL), as Cook Medical is launching the Perc NGage® and Perc NCompass® nitinol stone extractors today. The new products complement the Perc NCircle®, which has been on the market since 2002 and was the first nitinol extraction device for percutaneous procedures. Cook Medical was the first company to incorporate nitinol into its stone extraction devices.

From COOK MEDICAL INC. 26 Nov 2014

Quarter of all obesity-related cancers in 2012 attributed to increasing BMI, say researchers

Based on the results, the researchers led by Dr Melina Arnold from the International Agency for Research on Cancer, estimate that a quarter of all obesity-related cancers in 2012 (118 000 cases) were attributable to the rising average body mass index (BMI) in the population since 1982, and were therefore "realistically avoidable".

26 Nov 2014

Presence of certain proteins in HDL can lead to cardiovascular risk

A current study by the MedUni Vienna has shown that changes to the "good cholesterol" HDL (High-Density Lipoprotein) can be associated with cardiovascular diseases: by developing a new laboratory test, scientists at the Institute of Medical Genetics and the Department of Nephrology & Dialysis (University Department of Internal Medicine III) at the MedUni Vienna have demonstrated for the first time that the presence of certain proteins in the HDL can lead to an increased risk of cardiovascular disease and mortality.

26 Nov 2014

CHMP approves Victoza for use in adults with type 2 diabetes, moderate renal impairment

The Committee for Medicinal Products for Human Use today issued a positive opinion for the use of Victoza (liraglutide) in adults with type 2 diabetes and moderate renal impairment.

25 Nov 2014

UL professor awarded HRB grant to improve understanding of Acute Kidney Injury

It is estimated that at least 1 in 5 hospitalised adults develop Acute Kidney Injury (AKI). Emerging evidence suggests that AKI: is under-recognised in clinical practice; predicts an accelerated risk of end-stage kidney disease (ESKD), and may be a risk amplifier for many other chronic diseases with death rates in excess of 20%.

24 Nov 2014

Endocrine Society issues Clinical Practice Guideline on rare bone condition

The Endocrine Society today issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of Paget's disease of the bone, a condition where one or more bones in the body become oversized and weak.

23 Nov 2014

Investigational drug maintains normal potassium levels in patients with chronic kidney disease

Research published today found that the investigational drug patiromer decreased high potassium levels and maintained normal potassium levels in patients with chronic kidney disease. The results of a multicenter trial appear in the New England Journal of Medicine.

21 Nov 2014

Kidney disease patients can benefit from simple and structured exercise

Simple yet structured exercise can significantly improve kidney disease patients' quality of life as well as decrease their pain, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

21 Nov 2014

Majority of kidney dialysis patients not adequately prepared for emergency or natural disaster

Eighty percent of kidney dialysis patients surveyed were not adequately prepared in the event of an emergency or natural disaster that shut down their dialysis center.

20 Nov 2014

Scientists unravel molecular mechanisms that drive ferroptosis signaling

Ferroptosis is a recently recognized form of regulated necrosis. Up until now, this form of cell death has only been thought to be a possible therapeutic approach to treat tumour cells. Yet, ferroptosis also occurs in non-transformed tissues as demonstrated by this study, thus implicating this cell death pathway in the development of a wide range of pathological conditions. More specifically, the deletion of the ferroptosis-regulating enzyme Gpx4 in a pre-clinical model results in high ferroptosis rates in kidney tubular epithelial cells causing acute renal failure.

19 Nov 2014

Researchers find drug combination that reduces risk of skin graft rejection

A research team bringing together José Cohen and Philippe Grimbert (Inserm Unit 955/Université Paris Est Créteil [UPEC] and the Centre for Clinical Investigation - Biotherapies 504 [CIC-BT 504]), and their collaborators at Institut Curie and AP-HP (George Pompidou European Hospital) has succeeded in finding a combination of drugs that reduces the risk of rejection following a skin graft.

19 Nov 2014

Strict monitoring of lithium levels urged

Plasma levels of lithium above the advised range are associated with a transient reduction in kidney function, research shows.

19 Nov 2014

3SBio enters into exclusive license agreement with PharmAbcine for Tanibirumab

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced it has entered into an exclusive license with PharmAbcine, Inc. for the development, manufacturing and marketing of Tanibirumab, an anti-VEGFR2/KDR antibody for cancer in the territory of Greater China (including Mainland China, Taiwan, Hong Kong and Macau) and several emerging countries, including Thailand, Brazil and Russia.

18 Nov 2014

Researchers discover second protein associated with membranous nephropathy

An international team of researchers from France, Germany, and the US have identified a protein that turns a person's immune system against itself in a form of kidney disease called membranous nephropathy (MN). The new research was presented at ASN Kidney Week 2014 in Philadelphia and published online in the New England Journal of Medicine.

18 Nov 2014

Nephrology News and Research

Further Reading

PET/CT may improve differentiation of PTSD from MTBI

DFG to establish new Collaborative Research Centres

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

Immune-suppressing protein may predict how patients respond to treatment

External artificial pancreas improves glucose control, reduces hypoglycemia risk

Scientists make breakthrough in developing new treatment for advanced bladder cancer

Perc NGage® and Perc NCompass® nitinol stone extractors launched by Cook Medical

Quarter of all obesity-related cancers in 2012 attributed to increasing BMI, say researchers

Presence of certain proteins in HDL can lead to cardiovascular risk

CHMP approves Victoza for use in adults with type 2 diabetes, moderate renal impairment

UL professor awarded HRB grant to improve understanding of Acute Kidney Injury

Endocrine Society issues Clinical Practice Guideline on rare bone condition

Investigational drug maintains normal potassium levels in patients with chronic kidney disease

Kidney disease patients can benefit from simple and structured exercise

Majority of kidney dialysis patients not adequately prepared for emergency or natural disaster

Scientists unravel molecular mechanisms that drive ferroptosis signaling

Researchers find drug combination that reduces risk of skin graft rejection

Strict monitoring of lithium levels urged

3SBio enters into exclusive license agreement with PharmAbcine for Tanibirumab

Researchers discover second protein associated with membranous nephropathy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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