immunity News and Research

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How can we increase confidence in the COVID-19 vaccine?

In this interview, we speak to Professor Rishi Goyal and Professor Dennis Yi Tenen about their latest research that investigated COVID-19 vaccine hesitancy.

22 Dec 2021

Transcription factor Blimp1 identified as potential target for modulating T-reg activity to treat cancer

In cancer, a major obstacle to anti-tumor immunity and immunotherapy treatment is the infiltration of regulatory T cells, or T-reg cells, into a tumor. These immune cells generally turn down the immune response, and they can prevent the immune system from destroying cancer cells.

22 Dec 2021

Reprogramming immune system cells to strengthen against infections and cancer in geriatric patients

What if the key to aging well lies in reprogramming immune system cells to strengthen them against infections and cancer? Researchers at UT Southwestern are working to find out.

22 Dec 2021

Two-dose ChAdOx1 vaccine protection wanes after three months

New research reported in the journal The Lancet examines the temporal association between the two-dose ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccination regimen and the risk of severe outcomes from COVID-19 in Scotland vs. Brazil, where the Delta variant of SARS-CoV-2 was dominant and rare, respectively.

21 Dec 2021

Booster doses offer broader protection in SARS-CoV-2 infected and vaccinated individuals

Researchers determined IgG titers of vaccinated healthcare workers 11 months following primary COVID-19 vaccination.

21 Dec 2021

Effect of T cell reactivity in COVID-19 infection and vaccination

Researchers recently developed an immunodiagnostic T cell assay to classify T cell immune responses of the subjects based on their coronavirus disease 2019 infection and vaccination history.

21 Dec 2021

Stabilizing the long-term endemic behavior of COVID-19

Researchers used a classic age and contact structured model to explore the several reopening and vaccination coverage scenarios regarding the COVID-19 pandemic.

21 Dec 2021

Identifying a recurring pattern in broadly neutralizing antibodies that can target an epitope on SARS-CoV-2

Interesting research decrypts a recurring sequence in antibodies against severe acute respiratory syndrome 2 (SARS-CoV-2) and identifies it to be a board neutralizing antibody that targets a conserved epitope on the SARS-CoV-2 receptor-binding domain (RBD) of the spike protein.

21 Dec 2021

Estimating vaccine efficacy against COVID-like illness from omicron and other COVID-19 variants

A new study combines real-time syndromic surveillance data from daily cross-sectional surveys with a COVID-like illness (CLI) prevalence-based vaccine efficacy estimator to better explain the early onset of the omicron variant.

21 Dec 2021

Researchers create 'UV Curtain' that can sterilize rooms against coronaviruses

Researchers from the Ludwig Maximilian University of Munich have created a new system to protect areas from the virus, using a light-emitting diode (LED)-based ultraviolet C (UV-C) light curtain. Specific wavelengths of UV-C are known to inactivate viruses and bacteria, and this tool could help keep areas sterile.

20 Dec 2021

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

In a new study, published on the bioRxiv* preprint server, scientists showed in a mice model that three doses of the same synthetic peptide vaccine, eliciting an exclusive CD8+ T cell response against one SARS-CoV-2 Spike epitope, protected against lethal SARS-CoV-2 infection, in the absence of neutralizing antibodies. Researchers also showed that the third dose resulted in superior generation of effector-memory T cells in the circulation and tissue-resident memory T (TRM) cells.

20 Dec 2021

An Omicron wave predicted for England from December 2021 to April 2022

A study, published on the medRxiv* preprint server, focuses on the interaction between Omicron variants and public health interventions in England that promote immunity.

20 Dec 2021

Study casts light on how to combine antibiotics and phage therapy to fight bacterial infection

New research has moved a step closer to harnessing viruses to fight bacterial infection, reducing the threat of antibiotic resistance.

20 Dec 2021

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

The Omicron variant of SARS-CoV-2 may be significantly better than previous variants at evading vaccine-induced antibodies, according to new research from Cambridge - but preliminary evidence suggests it is less likely to cause severe COVID-19 illness in the lungs.

20 Dec 2021

immunity News and Research

How can we increase confidence in the COVID-19 vaccine?

Transcription factor Blimp1 identified as potential target for modulating T-reg activity to treat cancer

Reprogramming immune system cells to strengthen against infections and cancer in geriatric patients

Two-dose ChAdOx1 vaccine protection wanes after three months

Booster doses offer broader protection in SARS-CoV-2 infected and vaccinated individuals

Effect of T cell reactivity in COVID-19 infection and vaccination

Stabilizing the long-term endemic behavior of COVID-19

Identifying a recurring pattern in broadly neutralizing antibodies that can target an epitope on SARS-CoV-2

Estimating vaccine efficacy against COVID-like illness from omicron and other COVID-19 variants

Researchers create 'UV Curtain' that can sterilize rooms against coronaviruses

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

An Omicron wave predicted for England from December 2021 to April 2022

Study casts light on how to combine antibiotics and phage therapy to fight bacterial infection

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Researchers predict 200% increase in European coronavirus cases as Omicron spreads

A test to identify antibody effectiveness against COVID-19 variants

Anti-SARS-CoV-2 antibody infusion shown to demonstrate robust immune response following COVID-19 vaccination

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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