Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Advances in Cell Lineage Analysis

Dr. Jan Phillip Junker discusses the applications of CRISPR-Cas9 in cell lineage analysis and the development of tomo-seq; a method to study the spatial organization of cells within whole organisms.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

New findings point to potential therapeutic avenues for leukemia

Scientists have known for decades that the Hox family of transcription factors are key regulators in the formation of blood cells and the development of leukemia.

9 May 2018

Night shifts may have negative impact on long-term health

A team of researchers from the McGill University affiliated Douglas Mental Health University Institute (DMHUI) has discovered that genes regulating important biological processes are incapable of adapting to new sleeping and eating patterns and that most of them stay tuned to their daytime biological clock rhythms.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Cancer scientists confirm oligometastasis hypothesis

In 1995, two University of Chicago-based cancer specialists suggested there was an intermediate state - somewhere between curable localized cancers and lethal widespread disease - for patients with metastatic cancer.

7 May 2018

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

Castle Biosciences, Inc., the skin cancer diagnostics company providing molecular diagnostics to improve cancer treatment decisions, today announced the presentation of data supporting clinical use of the DecisionDx®-Melanoma test to inform sentinel lymph node biopsy (SLNB) recommendations.

7 May 2018

Discovery could be used as starting point for development of new antibiotics

According to the WHO, around 700,000 people die every year as a result of antibiotic resistance. In Germany, around 6,000 people die every year because treatment with antibiotics is not effective.

7 May 2018

Stimulant use may negatively affect health of HIV-positive persons

A researcher at the University of Miami Miller School of Medicine has found that the use of stimulants, such as methamphetamine, can negatively affect the health of HIV-positive persons even when they are adhering to medical treatment.

4 May 2018

Genes that control the immune system may play role in hair graying

A study has found a link between genes that warn our bodies of a pathogenic infection and genes that play a role in determining hair color.

4 May 2018

NASA finds new solutions for rapid in-flight molecular testing aboard the space station

What do astronauts, microbes, and plants all have in common? Each relies on deoxyribonucleic acid (DNA) - essentially a computer code for living things - to grow and thrive.

2 May 2018

New T cell biomarker could be much-needed patient-selection tool for CAR T cell therapy

Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia don't respond to chimeric antigen receptor T cell therapy, and the answer is tied to how primed patients' immune systems are before the therapy is administered.

30 Apr 2018

New optogenetic tools show promise in treating cardiovascular, neuropsychiatric disorders

You've heard of "nature versus nurture," and philosophers argue about which is more important. But how does this work on the cellular level?

27 Apr 2018

Plants provide a new avenue in curbing tumor growth

Plants have provided a new avenue in curbing tumor growth. On this occasion, it doesn't involve miracle species or the like, but rather the results obtained by the University of Cordoba BIO301 research team called "Epigenetics and DNA Repair."

27 Apr 2018

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment.

27 Apr 2018

Neonicotinoids may impact human health by disrupting hormonal systems, shows study

Neonicotinoids are currently the most widely used pesticides in the world and frequently make headlines because of their harmful effects on honeybees and other insect pollinators

27 Apr 2018

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

A Brazilian study published April 26 in the journal Cancer Research shows for the first time in vivo that Zika virus can be used as a tool to treat aggressive human central nervous system (CNS) tumors.

27 Apr 2018

Detailed genetic testing of head and neck cancers could lead to more personalized treatments

Research led by UNC School of Medicine student Wesley Stepp, PhD, shows how more detailed genetic testing of head and neck tumors could lead to more personalized treatments for patients.

26 Apr 2018

New UCLA study could elucidate certain causes of infertility and miscarriage

A new study in the journal Nature Cell Biology has uncovered information about a key stage that human embryonic cells must pass through just before an embryo implants. The research, led by UCLA biologist Amander Clark, could help explain certain causes of infertility and spontaneous miscarriage.

26 Apr 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

Gene Expression News and Research

Further Reading

Advances in Cell Lineage Analysis

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

New findings point to potential therapeutic avenues for leukemia

Night shifts may have negative impact on long-term health

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Cancer scientists confirm oligometastasis hypothesis

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

Discovery could be used as starting point for development of new antibiotics

Stimulant use may negatively affect health of HIV-positive persons

Genes that control the immune system may play role in hair graying

NASA finds new solutions for rapid in-flight molecular testing aboard the space station

New T cell biomarker could be much-needed patient-selection tool for CAR T cell therapy

New optogenetic tools show promise in treating cardiovascular, neuropsychiatric disorders

Plants provide a new avenue in curbing tumor growth

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Neonicotinoids may impact human health by disrupting hormonal systems, shows study

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

Detailed genetic testing of head and neck cancers could lead to more personalized treatments

New UCLA study could elucidate certain causes of infertility and miscarriage

Researchers target telomerase for killing NRAS-mutant melanoma cells

Industry Focus eBook - Biotechnology (4th edition) eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy