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First investigational xenotransplantation marks a major step towards adequate organ supply

The first investigational transplant of a genetically engineered, nonhuman kidney to a human body was recently completed at NYU Langone Health—marking a major step forward in potentially utilizing an alternative supply of organs for people facing life-threatening disease.

21 Oct 2021

Novel Einstein-developed strategy successfully suppresses HIV infections in mice

Armed with a novel strategy they developed for bolstering the body's immune response, scientists at Albert Einstein College of Medicine have successfully suppressed HIV infections in mice - offering a path to a functional cure for HIV and other chronic viral infections.

21 Oct 2021

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

By combining computational and experimental approaches, University of Pittsburgh School of Medicine and Prairie View A&M University researchers identified cancer drugs that show promise for treating pulmonary hypertension, or PH, a rare and incurable lung disease.

21 Oct 2021

UW Medicine receives NIH support to study aging cells

Efforts to understand aging cells in human tissues have received increased support from the National Institutes of Health.

20 Oct 2021

New discovery can pave the way to better diagnostics and therapeutics for asthma and COPD

Rutgers researchers have discovered that people with asthma and chronic obstructive pulmonary disease have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.

20 Oct 2021

Washington University receives $7.5 million to support NIH's research on senescent cells

Washington University School of Medicine in St. Louis is joining the National Institutes of Health's new research network focused on the study of senescent cells, a rare and important population of cells that is difficult to study but vital for understanding aging and the diseases of aging, including cancer and neurodegeneration.

20 Oct 2021

NIH launches new program to identify and characterize the differences in senescent cells

The National Institutes of Health has launched a program to study a rare type of cells, called "senescent" cells, that play both positive and negative roles in biological processes.

20 Oct 2021

UK government announces deals to secure two new COVID-19 treatments

Thousands of vulnerable patients could be taking ground-breaking COVID-19 antivirals this winter after the government announced deals to secure two new treatments.

20 Oct 2021

Cat bacteria likely to form the basis for novel therapeutics against severe skin infections

Researchers at University of California San Diego School of Medicine used bacteria found on healthy cats to successfully treat a skin infection on mice. These bacteria may serve as the basis for new therapeutics against severe skin infections in humans, dogs and cats.

20 Oct 2021

UQ start-up secures $1.3 million seed investment to develop new treatment for liver disease

A University of Queensland start-up company, developing a potential new treatment for obesity-related liver disease, has secured a seed investment of $1.3 million from IP Group, a UK-based intellectual property business.

19 Oct 2021

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

In a recent study published in the journal PLOS Pathogens, scientists showed that nasal administration of a single-domain antibody (VHH), named K-874A, brought about inhibition of SARS-CoV-2 titers in infected lungs of Syrian hamsters.

19 Oct 2021

Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

A group of researchers from various institutes in the USA addressed the limitations of BAT therapy by transplanting a low dose of brown adipocytes (BAs) without Matrigel to determine if this could alleviate high-fat diet-induced OB, metabolic symptoms, and T2DM in mice.

18 Oct 2021

New atlas of small cell lung cancer reveals rare population of stem-like cells with metastatic properties

Imagine you're about to go on a cross-country trip, stopping at spots along the way to admire local attractions.

15 Oct 2021

Ondansetron use associated with increased survival in mechanically ventilated COVID-19 patients

A recent study analyzes real-world data using artificial intelligence to provide insights into using ondansetron, an antiemetic agent, among SARS-CoV-2 positive patients.

14 Oct 2021

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

In a first-in-world clinical trial, researchers at Sunnybrook Health Sciences Centre in Toronto, Canada, have demonstrated that magnetic resonance (MR)-guided focused ultrasound can be used to safely deliver antibody therapy to breast cancer that has metastasized to the brain.

13 Oct 2021

FSU chemists develop a faster way to synthesize compounds for drug development

A team of Florida State University chemists has developed a faster way to synthesize a class of compounds that are commonly used in the development of new medications.

12 Oct 2021

Single-genome sequencing reveals malaria parasite genetics and evolution

Understanding how malaria parasites evolve after a human is bitten by an infected mosquito is very difficult. There can be billions of individual parasites in a patient's bloodstream and traditional genetic sequencing techniques can't identify the raw material for evolution: new mutations.

12 Oct 2021

Researchers uncover how cancer cells use sugar residue to evade the immune system

A team of South Dakota State University chemistry researchers uncovered how cancer cells utilize a simple sugar residue to disguise themselves from the immune system. What they learned will help scientists develop more effective cancer therapeutics.

12 Oct 2021

Research reveals components of Sinbis virus ribonucleoproteins

To address this gap in research regarding the understanding of post-replicative alphavirus RNPs, scientists have created a novel proteome-wide approach known as viral RNA interactome capture (vRIC). This study is available in the bioRxiv* preprint server while awaiting peer review.

11 Oct 2021

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Recently, scientists have developed a bacterial two-hybrid (B2H) system to study the PPIs of SARS-CoV-2 in a heterologous non-eukaryotic system. This study is available on the bioRxiv* preprint server. Put simply, the B2H system could be used to analyze the SARS-CoV-2 proteome.

11 Oct 2021

Therapeutics News and Research

First investigational xenotransplantation marks a major step towards adequate organ supply

Novel Einstein-developed strategy successfully suppresses HIV infections in mice

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

UW Medicine receives NIH support to study aging cells

New discovery can pave the way to better diagnostics and therapeutics for asthma and COPD

Washington University receives $7.5 million to support NIH's research on senescent cells

NIH launches new program to identify and characterize the differences in senescent cells

UK government announces deals to secure two new COVID-19 treatments

Cat bacteria likely to form the basis for novel therapeutics against severe skin infections

UQ start-up secures $1.3 million seed investment to develop new treatment for liver disease

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

New atlas of small cell lung cancer reveals rare population of stem-like cells with metastatic properties

Ondansetron use associated with increased survival in mechanically ventilated COVID-19 patients

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

FSU chemists develop a faster way to synthesize compounds for drug development

Single-genome sequencing reveals malaria parasite genetics and evolution

Researchers uncover how cancer cells use sugar residue to evade the immune system

Research reveals components of Sinbis virus ribonucleoproteins

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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