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First cases of co-infection with Delta and Omicron identified during local co-circulation of both SARS-CoV-2 lineages

Researchers revealed the co-infection of the SARS-CoV-2 Delta and Omicron variants in two epidemiologically unrelated patients suffering from chronic kidney disease and requiring hemodialysis

17 Feb 2022

Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Gene therapy trials for sickle cell disease have been showing great promise, even offering hope of a cure. But in early 2021, the trials ground to a halt after reports of blood malignancies in two people in a trial sponsored by bluebird bio.

16 Feb 2022

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Researchers discuss the genomic and virological characterization of SARS-CoV-2 variants among unvaccinated and vaccinated U.S military personnel.

16 Feb 2022

Study helps understand actionable genetic variation affecting drugs in the Middle East population

A group of researchers at Qatar Foundation have reported the first comprehensive study of the distribution of actionable genetic variation affecting drugs in any Middle Eastern population, with potential implications for preemptive pharmacogenomic implementation in the region.

16 Feb 2022

Omicron breakthrough boosts neutralization titers a little more than a 3rd COVID vaccine dose

Researchers compare the neutralizing antibody titers in individuals who received two or three mRNA vaccine doses and experienced breakthrough infections.

16 Feb 2022

SARS-CoV-2 variants are evolving increased infectivity and antibody escape, studies say

First announced by the World Health Organization on Nov. 26, 2021, the SARS-CoV-2 omicron variant spread rapidly around the world, becoming the dominant variant in the U.S. and elsewhere.

16 Feb 2022

Zebrafish model reveals how early embryo cells begin to independently produce proteins

It happens in the first hours after fertilization: The cells of the early embryo begin to independently produce proteins, the building blocks for cells and organs.

16 Feb 2022

Study confirms that pets can harbor SARS-CoV-2 infection

A new study looks at how dogs and cats within households are susceptible to COVID-19 infection from humans, and whether they act as reservoir species.

16 Feb 2022

COVID-19 related placental tissue destruction and insufficiency may cause stillbirth and neonatal death from hypoxic-ischemic injury

Researchers evaluate the role of the placenta in causing stillbirth and neonatal death post-maternal COVID-19 and confirmed placental positivity for SARS-CoV-2.

16 Feb 2022

Omicron RBD-ACE2 binding found to be stronger than wild type SARS-CoV-2 strain

Researchers recently investigated the effect of SARS-CoV-2 Omicron variant mutations on the binding of the receptor-binding domain and angiotensin-converting enzyme-2 to study the overall binding profile of the RBD-ACE2 system.

16 Feb 2022

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

The multiplex detection approach outlined in this study has the potential to address the need to rapidly characterize the phenotype and clinical response to continually emerging SARS-CoV-2 variants as the COVID-19 pandemic continues.

16 Feb 2022

The emergence of infectious diseases from the "germ’s eye view”

The study highlighted that the disruption caused by the COVID-19 pandemic has shown that human societies remain ill-prepared and susceptible to novel infectious diseases.

16 Feb 2022

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Researchers investigate SARS-CoV-2 mutations present across the whole genome of different SARS-CoV-2 variants.

15 Feb 2022

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Acne on the face is often treated with topical antibiotics, which tend to be used for an extended period of time and contribute to the serious problem of antibiotic resistance.

15 Feb 2022

Study explores rapid SARS-CoV-2 genome sequencing to help reduce hospital-acquired COVID-19 infections

In a new study, researchers examined whether SARS-CoV-2 whole-genome sequencing could be routinely used for infection prevention and control in hospitals.

15 Feb 2022

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

A new study published demonstrated the in vitro potencies of RDV and GS-441524 through PRA, and nucleoprotein ELISA against SARS-CoV-2 and other VOC/VOIs isolates with specific substitutions in Nsp12.

15 Feb 2022

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Single-cell RNA sequencing, or "scRNA-seq" for short, is a technique that allows scientists to study the expression of genes in an individual cell within a mixed population – which is virtually how all cells exist in the body's tissues.

15 Feb 2022

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

In a recent study posted to the bioRxiv* preprint server, a team of researchers from Washington, United States, investigated the transmission of viral genetic diversity during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) superspreading outbreak among the crew members on a fishing boat.

14 Feb 2022

First survey on Omicron BA.2 in France

In a recent study posted to the medRxiv* preprint server, researchers described the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 21L/BA.2 Omicron variant in south-eastern France.

14 Feb 2022

RNA capping mechanism of SARS-CoV-2 unveiled

In a recent study posted to the bioRxiv* preprint server, researchers elucidated the mechanism of ribonucleic acid (RNA) capping in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

14 Feb 2022

Genome News and Research

First cases of co-infection with Delta and Omicron identified during local co-circulation of both SARS-CoV-2 lineages

Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Study helps understand actionable genetic variation affecting drugs in the Middle East population

Omicron breakthrough boosts neutralization titers a little more than a 3rd COVID vaccine dose

SARS-CoV-2 variants are evolving increased infectivity and antibody escape, studies say

Zebrafish model reveals how early embryo cells begin to independently produce proteins

Study confirms that pets can harbor SARS-CoV-2 infection

COVID-19 related placental tissue destruction and insufficiency may cause stillbirth and neonatal death from hypoxic-ischemic injury

Omicron RBD-ACE2 binding found to be stronger than wild type SARS-CoV-2 strain

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

The emergence of infectious diseases from the "germ’s eye view”

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Study explores rapid SARS-CoV-2 genome sequencing to help reduce hospital-acquired COVID-19 infections

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

First survey on Omicron BA.2 in France

RNA capping mechanism of SARS-CoV-2 unveiled

Genetics & Genomics - Second Edition eBook

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The Critical Role of Sample Storage in Drug Discovery and Development

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