Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

SARS-CoV-2 beta variant elicits variant specific and cross-reactive antibodies

One recent study assessed the serum of Beta variant infected patients to determine whether major non-VOC antibodies could neutralize this virus.

5 Oct 2021

Anti-CD20 therapy patients can develop immune responses after SARS-CoV-2 vaccination

A new systematic review and meta-analysis focused on the humoral and cell-mediated immune responses after COVID-19 vaccination in patients undergoing anti-CD20 antibodies treatment.

5 Oct 2021

Depressed seroconversion in immunocompromised COVID-19 vaccine recipients

Researchers from the University of Singapore have reviewed the data in post-vaccinated immunocompromised patients to examine the effectiveness of these vaccines in these patients.

5 Oct 2021

CAR-T cells require an abundance of antigens to efficiently kill solid tumors

Immunotherapy, which harnesses the power of the body's immune system to fight disease, is gaining huge traction in treating cancer.

5 Oct 2021

Humoral responses to SARS-CoV-2 are detectable through saliva, scientists find

Your saliva may be able to tell you if you’ve developed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies, suggests a new medRxiv* preprint study. In immunocompromised groups, salivary Immunoglobulin G (IgG) antibody levels were associated with IgG titers in blood serum 3 to 4 weeks after mRNA vaccination.

5 Oct 2021

SARS-CoV-2 mRNA vaccines elicit higher levels of antibodies compared to natural infection

Researchers from the US recently characterized the scale and specificity of SARS-CoV-2 spike-reactive antibodies from 23 participants who received SARS-CoV-2 mRNA vaccines and 10 acutely infected health care workers. They found that primary mRNA vaccination and infection elicited S1- and S2-reactive antibodies, while secondary mRNA vaccination elicited mostly S1 antibodies.

4 Oct 2021

Fully vaccinated people with prior SARS-CoV-2 infection have more memory B cells, study shows

A new study by University of Minnesota Medical School researchers is revealing that some people who received an mRNA vaccination for COVID-19 have greater immune responses compared to others.

4 Oct 2021

Study looks at immunosuppressants and COVID vaccine efficacy

Researchers investigate the effects of five established immunosuppressant medications following COVID-19 vaccination.

4 Oct 2021

How durable is the immune response generated from the BNT162b2 vaccine?

In a recent study, researchers analyzed antibody responses to the homologous Wu strain and several other SARS-CoV-2 variants after BNT162b2 vaccination.

4 Oct 2021

mRNA vaccination induces strong humoral immune responses against SARS-CoV-2 in over 80's

A recent study assesses the serological and cellular responses to Pfizer’s BNT162b2 mRNA vaccine in people aged 80-96 years.

4 Oct 2021

Antibody kinetics after natural SARS-CoV-2 infection and COVID-19 vaccination in Hispanic/Latino population

A new study addressing this issue has been published in Viruses that shows that functional neutralizing antibody tests are more relevant indicators than the presence or absence of binding antibodies.

4 Oct 2021

Difficulties of stability and storage of mRNA COVID-19 vaccines

Two researchers have collaborated to review the difficulties faced in storing and transporting these vaccines in a manner that will keep them stable.

4 Oct 2021

Breakthrough research reveals why some Covid patients may die from the disease

The number of Covid cases in the UK has risen 12% this week, but while some people may be hospitalized, others will suffer little more than a loss of smell. London Medical Laboratory says new research is now revealing everyone’s immune system is as unique as their fingerprint.

4 Oct 2021

Study provides insights on kidney transplant recipients’ immune response to SARS-CoV-2 infection

New research provides insights on the immune responses of kidney transplant recipients following infection with the virus that causes COVID-19. The study, which is published in JASN, may help explain why these individuals face a higher risk of dying from COVID-19 than others in the general population.

4 Oct 2021

Using a new public antibody to understand SARS-CoV-2 neutralization

SARS-CoV-2 infects host cells by binding to the angiotensin convertase 2 receptor (ACE2) on the cell surface through its trimeric spike (S) protein. SARS-CoV enters host human cells through endosomes, while SARS-CoV-2 enters through the cell surface and endosomes. The present study published in the journal “Cell Reports” aimed to understand the mechanisms of SARS-CoV-2 antibody neutralization to facilitate the development of therapeutic interventions for COVID-19.

4 Oct 2021

REGEN-COV shown to reduce risk of COVID-19–related hospitalization or death from any cause

The phase 1-2 clinical trials conducted using REGEN-COV had shown promising therapeutic benefits in COVID-19 outpatients. Its effect was further investigated in the present phase 3 clinical trial, the findings of which have been published in the "The New England Journal of Medicine".

3 Oct 2021

Immune response to SARS-CoV-2 variants of concern after natural infection or vaccination

A recent review paper published in the MDPI's journal Viruses highlights how available vaccines may be effective in protecting individuals against severe forms of coronavirus disease 2019 (COVID-19), but the protection against infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its transmission to others may be reduced – with consequences for community protection and herd immunity.

3 Oct 2021

Antibody News and Research

Further Reading

SARS-CoV-2 beta variant elicits variant specific and cross-reactive antibodies

Anti-CD20 therapy patients can develop immune responses after SARS-CoV-2 vaccination

Depressed seroconversion in immunocompromised COVID-19 vaccine recipients

CAR-T cells require an abundance of antigens to efficiently kill solid tumors

Humoral responses to SARS-CoV-2 are detectable through saliva, scientists find

SARS-CoV-2 mRNA vaccines elicit higher levels of antibodies compared to natural infection

Fully vaccinated people with prior SARS-CoV-2 infection have more memory B cells, study shows

Study looks at immunosuppressants and COVID vaccine efficacy

How durable is the immune response generated from the BNT162b2 vaccine?

mRNA vaccination induces strong humoral immune responses against SARS-CoV-2 in over 80's

Antibody kinetics after natural SARS-CoV-2 infection and COVID-19 vaccination in Hispanic/Latino population

Difficulties of stability and storage of mRNA COVID-19 vaccines

Breakthrough research reveals why some Covid patients may die from the disease

Study provides insights on kidney transplant recipients’ immune response to SARS-CoV-2 infection

Using a new public antibody to understand SARS-CoV-2 neutralization

REGEN-COV shown to reduce risk of COVID-19–related hospitalization or death from any cause

Immune response to SARS-CoV-2 variants of concern after natural infection or vaccination

Important factors that determine the child clinical COVID-19 attack ratio

Two-mAb cocktail prevents SARS-CoV-2 infection, study suggests

Enveloped virus-like particle based vaccines potentially broaden immunity against SARS-CoV-2 variants

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