Clinical Trial News and Research

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Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

The Damon Runyon Cancer Research Foundation has named five new Damon Runyon Clinical Investigators.

6 Jul 2022

Outpatient antibiotic management of patients with appendicitis is safe, helps avoid surgery

Outpatient antibiotic management of selected patients with appendicitis is safe, allowing many patients to avoid surgery and hospitalization, and should be considered as part of shared decision-making between doctor and patient.

6 Jul 2022

What is the optimal LDL cholesterol level for patients with cardiovascular diseases?

In a new study, the effectiveness of low low-density lipoprotein cholesterol levels in reducing the risk of atherosclerotic vascular events was explored.

6 Jul 2022

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

A new study assessed both placebo and vaccine recipients in the mRNA-1273 (Moderna) phase 3 clinical trial who were infected with SARS-CoV-2 during the blinded, placebo-controlled trial phase.

6 Jul 2022

Trial: Convalescent plasma does not improve survival or recovery in hospitalized COVID-19 patients

Convalescent plasma, widely given to severely ill patients hospitalized with COVID-19 during the pandemic, does not improve their ability to survive or recover, according to a national clinical trial led by Vanderbilt University Medical Center and published in the journal CHEST.

5 Jul 2022

Intensive nurse home visiting program did not improve birth outcomes for low-income mothers, finds study

A paper in the Journal of the American Medical Association found that Nurse-Family Partnership (NFP), a prenatal and early child home visiting program, did not improve birth outcomes for low-income mothers in South Carolina.

5 Jul 2022

Risk of eczema in babies could be lowered by taking vitamin D supplements during pregnancy

Taking Vitamin D supplements during pregnancy could substantially reduce the chances of babies up to a year old suffering from atopic eczema, according to a new study by University of Southampton researchers.

5 Jul 2022

Politicians have a considerable survival benefit over general populations, finds study

New data show politicians have a considerable survival advantage over general populations, based on information from 11 countries and over 57,500 politicians.

5 Jul 2022

BICO; Combining Life Sciences Solutions to Further Human Health

As part of our SLAS Europe 2022 coverage, we speak to Héctor Martínez, CTO of BICO, about the technology and services they offer within life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 5 Jul 2022

Greater global coordination needed for AI-enhanced diagnostics, treatment to save lives of prostate cancer patients

The largest prostate cancer biopsy dataset – involving over 95,000 images – has been created by researchers in Sweden to ensure AI can be trained to diagnose and grade prostate cancer for real world clinical applications.

3 Jul 2022

Portable biosensor device for early detection of chronic kidney disease

A new method for early detection of chronic kidney disease, which affects an estimated 7% of the world’s population, has been shown to have potential to service rural and remote patients and communities with limited medical services.

1 Jul 2022

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

A team of clinician-scientists and scientists, led by the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore together with collaborators in Europe and South Korea, used single-cell techniques to uncover a central dichotomy for colorectal cancer cells, leading to a proposed update of the classification system for the disease.

1 Jul 2022

HIV accelerates epigenetic aging soon after initial HIV infection

HIV has an "early and substantial" impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection, according to a study by UCLA researchers and colleagues.

1 Jul 2022

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

In a recent article posted to the bioRxiv* preprint server, researchers at Rutgers, the State University of New Jersey, the University of South Florida, and the Catholic University of America demonstrated that the natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) mutations result in nirmatrelvir resistance.

30 Jun 2022

Better, safer treatment option than saline solution may be available for hospital patients

A new study by researchers at Intermountain Healthcare in Salt Lake City finds there may be a better and safer treatment option for emergency department and hospital patients than saline solution, which is used as an IV fluid and is one of the most prescribed medical therapies in the United States.

30 Jun 2022

Awake prone positioning does not reduce endotracheal intubation for COVID-19 patients with acute hypoxemia

A large multicenter, randomized clinical trial revealed no difference in the risk of endotracheal intubation requirement at 30 days between awake prone positioning and standard positioning for patients with COVID-19 who suffered from acute hypoxemic respiratory failure, according to research published in JAMA by researchers at UTHealth Houston.

29 Jun 2022

Analysis finds variation in the management of mantle cell lymphoma across clinical settings

There is considerable variation in the management of mantle cell lymphoma across different clinical settings, and some strategies do not always conform with what might be expected, according to an analysis by investigators from Weill Cornell Medicine and other leading health institutions.

28 Jun 2022

UC enrolling patients for clinical trial of novel PTSD treatments

About 8% of Americans will experience post-traumatic stress disorder at some point in their lives, but there are still few effective options to treat the condition.

28 Jun 2022

Acute illness increases cortisol levels in children and adolescents

A new study reports that in children and adolescents without glucocorticoid deficiency, circulating cortisol levels were higher during acute illnesses.

28 Jun 2022

Penn Medicine receives $9 million to advance research on imaging technology that illuminates tumors

Building on Penn Medicine's years of research and use of imaging technology that illuminates tumor tissue - helping clinicians more easily detect and remove it - the Perelman School of Medicine at the University of Pennsylvania has received a five-year, $9 million research grant from the National Cancer Institute (NCI) to push the field forward, particularly for lung cancer patients.

28 Jun 2022

Clinical Trial News and Research

Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

Outpatient antibiotic management of patients with appendicitis is safe, helps avoid surgery

What is the optimal LDL cholesterol level for patients with cardiovascular diseases?

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

Trial: Convalescent plasma does not improve survival or recovery in hospitalized COVID-19 patients

Intensive nurse home visiting program did not improve birth outcomes for low-income mothers, finds study

Risk of eczema in babies could be lowered by taking vitamin D supplements during pregnancy

Politicians have a considerable survival benefit over general populations, finds study

BICO; Combining Life Sciences Solutions to Further Human Health

Greater global coordination needed for AI-enhanced diagnostics, treatment to save lives of prostate cancer patients

Portable biosensor device for early detection of chronic kidney disease

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

HIV accelerates epigenetic aging soon after initial HIV infection

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

Better, safer treatment option than saline solution may be available for hospital patients

Awake prone positioning does not reduce endotracheal intubation for COVID-19 patients with acute hypoxemia

Analysis finds variation in the management of mantle cell lymphoma across clinical settings

UC enrolling patients for clinical trial of novel PTSD treatments

Acute illness increases cortisol levels in children and adolescents

Penn Medicine receives $9 million to advance research on imaging technology that illuminates tumors

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