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Post-exposure doxycycline approach leads to two-thirds reduction in STI incidence

The oral antibiotic doxycycline prevented the acquisition of sexually transmitted infections (STIs) when tested among men who have sex with men (MSM) and transgender women who took the medication within 72 hours of having condomless sex, according to findings published today in the New England Journal of Medicine.

6 Apr 2023

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Researchers assess the role of the live-attenuated vaccine sCPD9 in inducing systemic and mucosal immunity against SARS-CoV-2 variants.

6 Apr 2023

The economic burden of RSV infections in low and middle-income countries

Researchers discuss the cost-of-illness associated with RSV infections among children in low and middle-income countries.

6 Apr 2023

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Global antimicrobial resistance: socioeconomic factors play an underappreciated role in the spread

Researchers investigated the association between rates of antimicrobial resistance in animals and humans and environmental, socioeconomic, and anthropogenic indicators.

6 Apr 2023

Study reviews the diagnosis and treatment of acute myocarditis

Scientists have recently reviewed and summarized the evidence regarding diagnosing and treating acute myocarditis.

6 Apr 2023

mAb therapy reduces risk of hospitalization and death against Alpha, Delta, and Omicron variants

Researchers assess the efficacy of monoclonal antibodies in treating COVID-19 caused by different viral variants.

6 Apr 2023

Can fecal microbiota be administered safely and efficiently to prevent Clostridiodes difficile infection?

Researchers assessed the safety and efficacy of fecal microbiota in preventing Clostridiodes difficile infection.

6 Apr 2023

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Researchers assessed the extent of SARS-CoV-2 Omicron VOC BA.5 sub-VOC infection-associated brain infection and death.

5 Apr 2023

Using brain organoids to test gene therapies for a rare disease in children

Brain tissue grown in a laboratory by University of Queensland researchers will be used to test a treatment for a rare disease in children and help unlock therapies for a range of neurological disorders.

5 Apr 2023

Long-term protection and high efficacy of bivalent BA.1 booster confirmed in older adults

Researchers estimated the duration of protection with monovalent vaccination and the efficacy of bivalent vaccine boosters.

5 Apr 2023

Antioxidant supplementation shows potential to improve male fertility

A new study discusses the benefits of antioxidant supplementation on male fertility.

4 Apr 2023

Novel immunotherapy-based approach for low-grade lymphomatoid granulomatosis improves patient survival

Results from a clinical trial conducted by researchers at the National Institutes of Health (NIH) show that people with low-grade lymphomatoid granulomatosis who are treated with interferon alfa-2b, a type of immunotherapy, can live for decades after diagnosis.

4 Apr 2023

Innovative approach to customize treatments for colorectal cancer

Using AI to enhance the performance of surgeons: decoding intraoperative surgical activity via accurate machine learning systems

Researchers proposed the utilization of a vision transformer model to decode surgeon activities from surgical videos.

3 Apr 2023

Efficacy News and Research

Post-exposure doxycycline approach leads to two-thirds reduction in STI incidence

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

The economic burden of RSV infections in low and middle-income countries

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

Global antimicrobial resistance: socioeconomic factors play an underappreciated role in the spread

Study reviews the diagnosis and treatment of acute myocarditis

mAb therapy reduces risk of hospitalization and death against Alpha, Delta, and Omicron variants

Can fecal microbiota be administered safely and efficiently to prevent Clostridiodes difficile infection?

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Using brain organoids to test gene therapies for a rare disease in children

Long-term protection and high efficacy of bivalent BA.1 booster confirmed in older adults

Antioxidant supplementation shows potential to improve male fertility

Novel immunotherapy-based approach for low-grade lymphomatoid granulomatosis improves patient survival

Innovative approach to customize treatments for colorectal cancer

Live attenuated nasal vaccine elicits superior immunity to SARS-CoV-2 variants in hamsters

Overcoming challenges in flavivirus vaccine development: Exploring modern vaccine types for Dengue, Zika, and beyond

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Crystal engineering strategy could make medicines more soluble and palatable for children

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Using AI to enhance the performance of surgeons: decoding intraoperative surgical activity via accurate machine learning systems

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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