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Ohio appeals court reinstates claim that diet drug Redux should not have been marketed

An Ohio Federal Court of Appeals ruling issued yesterday is reinstating the late victim's claim that the recalled diet drug Redux (commonly called fen-phen) linked to her death should never have been marketed to the American people by Wyeth due in part to its pre-approval concerns about potentially lethal side effects.

20 Aug 2010

Genetic architecture controlling growth of 'back-up' blood vessels uncovered

Researchers at the University of North Carolina at Chapel Hill School of Medicine have uncovered the genetic architecture controlling the growth of the collateral circulation - the "back-up" blood vessels that can provide oxygen to starved tissues in the event of a heart attack or stroke.

20 Aug 2010

AHRQ grant allows Premier Perinatal Safety Initiative to develop birth-related injury reduction tehniques

The Department of Health & Human Services' Agency for Healthcare Research and Quality (AHRQ) has awarded a three-year demonstration grant for not-for-profit entities to Fairview Health Services in Minneapolis to extend a national collaborative that is reducing birth-related injuries.

20 Aug 2010

ISCO to formalize eye care based stem cell therapeutic programs into Cytovis business unit

International Stem Cell Corporation, today announced that its stem cell therapeutic programs focused on protective, transparent corneas (CytoCor™) in the front of the eye and the light-sensitive retinal tissue (CytoRet™) in the back of the eye will be formalized into a new business unit, Cytovis™.

20 Aug 2010

Research on gut mucosa enables effective drug treatment for irritable bowel syndrome

Irritable bowel syndrome makes life miserable for those affected an estimated ten percent or more of the population. And what irritates many of them even more is that they often are labeled as hypochondriacs, since physical causes for irritable bowel syndrome have never been identified. Now, biologists at the Technische Universitaet Muenchen (TUM) have shed new light on the matter: They have discovered mini-inflammations in the mucosa of the gut, which upset the sensitive balance of the bowel and are accompanied by sensitization of the enteric nervous system.

20 Aug 2010

SIR-Spheres safe, effective for patients with colorectal cancer liver metastases who have failed chemotherapy

Radioactive yttrium-90 labelled resin microspheres (SIR-Spheres; Sirtex Medical, Sydney, Australia) appear to be a safe and effective treatment for patients with colorectal cancer liver metastases who have failed available chemotherapy options, according to the final results of a prospective clinical multi-centre phase II trial conducted by the Italian Society of Locoregional Therapies in Oncology (SITILO) and published in the British Journal of Cancer.

20 Aug 2010

Study finds ketamine restores connection in chronic stress affected brain cells

Yale researchers have discovered how a novel anti-depressant can take effect in hours, rather than the weeks or months usually required for most drugs currently on the market.

20 Aug 2010

Bacterial pathogens require vitamin B6 biosynthesis enzymes for virulence: Study

Scientists have determined that Helicobacter pylori, the bacterium that causes peptic ulcers and some forms of stomach cancer, requires the vitamin B6 to establish and maintain chronic infection, according to research published this week in the online journal mBio-. This finding, along with the identification of the enzyme the microbe requires to utilize the vitamin, could lead to the development of an entirely new class of antibiotics.

20 Aug 2010

Scientists discover genetic flaw that causes facioscapulohumeral muscular dystrophy

Nearly two decades after they identified the specific genetic flaw that causes a common type of muscular dystrophy, scientists believe they have figured out how that flaw brings about the disease. The finding by an international team of researchers settles a longstanding question about the roots of facioscapulohumeral muscular dystrophy or FSHD.

20 Aug 2010

FDA Advisory Committee votes in favor of expanding pain indications for Eli Lilly's Cymbalta

The U.S. Food and Drug Administration (FDA) Anesthetic and Life Support Drugs Advisory Committee voted 8-6 in favor of expanding the pain indications for Eli Lilly and Company's (NYSE: LLY) Cymbalta® (duloxetine HCl) to a broader pain population that will be further defined by the FDA, if approved.

20 Aug 2010

Renin test can predict appropriate drugs for BP patients: Study

Commonly prescribed drugs used to lower blood pressure can actually have the opposite effect-raising blood pressure in a statistically significant percentage of patients. A new study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that doctors could avoid this problem-and select drugs most suitable for their patients-by measuring blood levels of the enzyme renin through a blood test that is becoming more widely available. The study appears in the online edition of the American Journal of Hypertension.

20 Aug 2010

Research marks new direction to treat Pneumocystis, inflammatory diseases

A drug to treat inflammation plays a surprising role reducing the level of infection caused by an opportunistic bug that is deadly for AIDS and cancer patients and others with weakened immune systems.

20 Aug 2010

Muscular Dystrophy Association awards $14.1M in new grants

The Muscular Dystrophy Association, which has invested almost $39 million in 2010 in worldwide research seeking treatments and cures for muscle diseases, today announced that it has awarded $14.1 million in new grants.

20 Aug 2010

FDA grants priority review designation of BENLYSTA for systemic lupus erythematosus treatment

Human Genome Sciences, Inc. and GlaxoSmithKline PLC today announced that the U.S. Food and Drug Administration has granted a priority review designation to BENLYSTA (belimumab) as a potential treatment for systemic lupus erythematosus.

20 Aug 2010

First Edition: August 19, 2010

In the news today, modest premium increases are ahead for Medicare drug plans while a survey finds that big employers expect health cost hikes in 2011.

20 Aug 2010

Novartis sales representatives increase calls to healthcare providers by 7%: SDI report

In the first 6 months of 2010, according to SDI, calls made by Novartis sales representatives to physicians, nurse practitioners, and physician assistants increased 7% compared with the last 6 months of 2009.

19 Aug 2010

PAREXEL International launches temperature recording solution optimized for clinical trial supply process

PAREXEL International Corporation, a leading global biopharmaceutical services organization, today announced that it has introduced an integrated temperature recording solution for study drug transportation as part of its expanded Clinical Logistics Services.

From Parexel 19 Aug 2010

PharmaVentures announces global expansion of PharmaDeals Agreements

PharmaVentures, the company behind the PharmaDeals(R) range of business information, announced today the expansion of its PharmaDeals Agreements coverage that includes exclusive interviews with deal makers around the world. The announcement follows major enhancement of its dedicated, market leading platform delivering deal data and information to the pharmaceutical and biotechnology sector.

19 Aug 2010

Effects of illegal drugs on health

Illegal drugs are responsible for up to 1,600 deaths a year in the UK, and destroy thousands of relationships, families and careers. Find out about the most commonly used illegal drugs in England and Wales and the effects they can have on your health.

19 Aug 2010

Celera Corporation releases review article on KIF6 gene variant for CHD

Celera Corporation today announced the publication of a review article on the KIF6 gene variant as a predictor of risk of coronary heart disease (CHD) and reduction of CHD events from statin therapy.

19 Aug 2010

Drugs News and Research

Ohio appeals court reinstates claim that diet drug Redux should not have been marketed

Genetic architecture controlling growth of 'back-up' blood vessels uncovered

AHRQ grant allows Premier Perinatal Safety Initiative to develop birth-related injury reduction tehniques

ISCO to formalize eye care based stem cell therapeutic programs into Cytovis business unit

Research on gut mucosa enables effective drug treatment for irritable bowel syndrome

SIR-Spheres safe, effective for patients with colorectal cancer liver metastases who have failed chemotherapy

Study finds ketamine restores connection in chronic stress affected brain cells

Bacterial pathogens require vitamin B6 biosynthesis enzymes for virulence: Study

Scientists discover genetic flaw that causes facioscapulohumeral muscular dystrophy

FDA Advisory Committee votes in favor of expanding pain indications for Eli Lilly's Cymbalta

Renin test can predict appropriate drugs for BP patients: Study

Research marks new direction to treat Pneumocystis, inflammatory diseases

Muscular Dystrophy Association awards $14.1M in new grants

FDA grants priority review designation of BENLYSTA for systemic lupus erythematosus treatment

First Edition: August 19, 2010

Novartis sales representatives increase calls to healthcare providers by 7%: SDI report

PAREXEL International launches temperature recording solution optimized for clinical trial supply process

PharmaVentures announces global expansion of PharmaDeals Agreements

Effects of illegal drugs on health

Celera Corporation releases review article on KIF6 gene variant for CHD

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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