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Treatment with DMARDs reduces rheumatoid arthritis disability: Study

For people living with rheumatoid arthritis (RA), the level of disease activity measured using the standard DAS 28 score is the factor most strongly affecting the level of RA-related disability, according to a study in Journal of Clinical Rheumatology.

19 Aug 2010

Policy restrictions for certain medications lead to decreased drug use and substantial savings for insurers

Policies that restrict reimbursement for certain medications can save money for health insurers without driving patients to seek other kinds of health care, a new review of studies suggests.

19 Aug 2010

Cognition Therapeutics receives grant to develop small-molecule drug candidate for Alzheimer's disease

The Alzheimer's Drug Discovery Foundation (ADDF) announced today that it has awarded a grant of $228,668 to Cognition Therapeutics (CogRx) to develop small molecule drugs that block the action of the toxic "oligomers" thought responsible for Alzheimer's disease (AD).

19 Aug 2010

MD Anderson Cancer Center receives $20 million to advance research on targeted therapies

Dallas businessman and philanthropist H. Ross Perot has donated $20 million to The University of Texas MD Anderson Cancer Center for research to advance and design novel targeted therapies.

19 Aug 2010

U-M research results show potential for discovering new avenues for anti-aging drugs

A team of University of Michigan scientists has found that suppressing a newly discovered gene lengthens the lifespan of roundworms. Scientists who study aging have long known that significantly restricting food intake makes animals live longer. But the goal is to find less drastic ways to achieve the same effect in humans someday. The U-M results offer promising early evidence that scientists may succeed at finding targets for drugs that someday could allow people to live longer, healthier lives.

19 Aug 2010

Scientists reveal lab approach method to treat neuroblastoma in children

A study led by scientists at The Hospital for Sick Children (SickKids) reveals a new method of identifying drugs to treat children suffering from fatal cancers for which an effective treatment has not been found. Rather than developing a new drug from scratch, which is a complicated and time-consuming process, they tried a different approach: in the lab, they tested existing drugs on cancer stem cells from young patients with neuroblastoma, one of the common cancers of infants and children.

19 Aug 2010

FDA accepts to review Bristol-Myers Squibb's ipilimumab for melanoma

Bristol-Myers Squibb Company today announced that the U.S. Food and Drug Administration (FDA) has accepted, for filing and review, the Biologics License Application (BLA) for ipilimumab for the treatment of adult patients with advanced melanoma who have been previously treated. The company also announced today that the application has been granted a priority review designation by the FDA.

19 Aug 2010

Achillion Pharmaceuticals enters agreement to raise $50.1 million from sale of common stock

Achillion Pharmaceuticals, Inc., a leader in the discovery and development of small molecule drugs to combat the most challenging infectious diseases, today announced that it has entered into definitive agreements for the purchase of $50.1 million of Achillion's common stock and warrants in a private placement financing with a select group of institutional and accredited investors, namely Domain Associates, Clarus Ventures, Quaker BioVentures and Pappas Ventures.

19 Aug 2010

China PharmaHub and Chengdu Yongkon Pharmacy sign cooperation agreement

China PharmaHub Corp., recently merged with World Wide Relics, which will be shortly changing its name to China PharmaHub Corp, is proud to announce it has signed a cooperation agreement with Chengdu Yongkon Pharmacy Co. Ltd., a pharmaceutical company based in Sichuan, with an established sales network of over 2600 hospitals in China.

18 Aug 2010

Pharmacies in Massachusetts to make available lock boxes for sale

On August 9, 2010 Massachusetts passed Chapter 283 of the Acts of 2010, adding Safeguards to the Prescription Monitoring Program and furthering Substance Abuse Education and Prevention. Section 11 of the act requires all pharmacies in Massachusetts that dispense schedule II, III, IV, or V prescription drugs to make available lock boxes for sale at each location.

18 Aug 2010

PBM Medco invests in comparative-effectiveness, safety research firm

The Wall Street Journal reports that pharmacy benefit manager Medco Health Solutions will buy United BioSource, a business that conducts safety and comparative effectiveness research, for $730 million.

18 Aug 2010

FDA grants orphan drug designation to NephRx's lead product NX001

NephRx Corporation today announced that the U.S. Food and Drug Administration has granted orphan drug designation to its lead product NX001 for the prevention of delayed graft function in renal transplant recipients. NX001 is a kidney growth factor peptide that has demonstrated good safety and promising efficacy in two animal models of acute renal failure.

18 Aug 2010

Aggressive children more inclined to misuse drugs

Aggressive and hyperactive boys with low parental monitoring are more likely to befriend deviant peers and become heavy drug users as teens, according to a new study published in the journal Addictive Behaviors. Yet the investigation by scientists from the Universit- de Montr-al and Sainte-Justine University Hospital Research Center found that bad boys can be protected from heavy substance use as teenagers if they are highly monitored and befriend good boys as children.

18 Aug 2010

World Bank to provide $900M in emergency funding for Pakistan floods, country's High Commissioner provides rough damage estimate

The World Bank on Monday "pledged to reroute money from other projects to provide $900 million in emergency funding to help Pakistan" with its flood recovery efforts, the New York Times reports (Ellick, 8/17).

18 Aug 2010

Study finds pharmaceuticals as a two-tier market for producing 'lemons' and serious harm

The pharmaceutical industry is a "market for lemons," a market in which the seller knows much more than the buyer about the product and can profit from selling products less effective and less safe than consumers are led to believe, according to an analysis that will be presented at the 105th Annual Meeting of the American Sociological Association.

18 Aug 2010

Policies, practices concerning MRSA differ among acute-care hospitals in the U.S.: Researchers

Hospitals vary in how they detect and treat drug-resistant staph infections, but most follow national guideline recommendations, according to researchers at the University of Illinois at Chicago.

18 Aug 2010

MDA awards $14.1 million in new grants to advance treatments and cures for muscle diseases

The Muscular Dystrophy Association, which has invested almost $39 million in 2010 in worldwide research seeking treatments and cures for muscle diseases, today announced that it has awarded $14.1 million in new grants.

18 Aug 2010

UK scientists receive Royal Society awards for cancer research

Two Cancer Research UK scientists were recently awarded prestigious Royal Society Awards, while a number of Cancer Research UK scientists were elected fellows of the Royal Society and the Academy of Medical Sciences.Dr Tomas Lindahl is the recipient of the Royal Society Copley Medal, the world's oldest prize for scientific achievement, and Professor Stephen West is awarded this year's GlaxoSmithKline Prize and Lecture.

18 Aug 2010

Lilly to halt development of potential Alzheimer's disease drug semagacestat

Eli Lilly and Company will halt development of semagacestat, a gamma secretase inhibitor being studied as a potential treatment for Alzheimer's disease, because preliminary results from two ongoing long-term Phase III studies showed it did not slow disease progression and was associated with worsening of clinical measures of cognition and the ability to perform activities of daily living.

18 Aug 2010

Researcher identifies immune system's ability to protect body against lung cancer

A Michigan State University researcher is analyzing the immune system's own ability to protect the body against lung cancer.The results of the work by Alison Bauer, an assistant professor of pathobiology and diagnostic investigation in the College of Veterinary Medicine, are expected to provide new approaches to prevent, identify and treat lung cancer.

18 Aug 2010

Drugs News and Research

Treatment with DMARDs reduces rheumatoid arthritis disability: Study

Policy restrictions for certain medications lead to decreased drug use and substantial savings for insurers

Cognition Therapeutics receives grant to develop small-molecule drug candidate for Alzheimer's disease

MD Anderson Cancer Center receives $20 million to advance research on targeted therapies

U-M research results show potential for discovering new avenues for anti-aging drugs

Scientists reveal lab approach method to treat neuroblastoma in children

FDA accepts to review Bristol-Myers Squibb's ipilimumab for melanoma

Achillion Pharmaceuticals enters agreement to raise $50.1 million from sale of common stock

China PharmaHub and Chengdu Yongkon Pharmacy sign cooperation agreement

Pharmacies in Massachusetts to make available lock boxes for sale

PBM Medco invests in comparative-effectiveness, safety research firm

FDA grants orphan drug designation to NephRx's lead product NX001

Aggressive children more inclined to misuse drugs

World Bank to provide $900M in emergency funding for Pakistan floods, country's High Commissioner provides rough damage estimate

Study finds pharmaceuticals as a two-tier market for producing 'lemons' and serious harm

Policies, practices concerning MRSA differ among acute-care hospitals in the U.S.: Researchers

MDA awards $14.1 million in new grants to advance treatments and cures for muscle diseases

UK scientists receive Royal Society awards for cancer research

Lilly to halt development of potential Alzheimer's disease drug semagacestat

Researcher identifies immune system's ability to protect body against lung cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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