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Previously unknown mechanism helps intestinal bacteria to affect formation of blood vessels

Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have discovered a previously unknown mechanism which helps intestinal bacteria to affect the formation of blood vessels. The results, which are presented in Nature, may provide future treatments of intestinal diseases and obesity.

27 Mar 2012

Study reveals clinically relevant differences between on pump and off pump bypass

A large randomized trial comparing bypass surgery done with a heart-lung machine (on pump) and without it (off pump) found no differences in results between techniques overall but some clinically relevant differences, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

High-risk, high-cost PCI patients can be identified through pre-procedure bleeding risk score

A pre-procedure bleeding risk score can accurately identify high-risk, high-cost patients and may provide an opportunity to employ bleeding avoidance strategies to improve patient outcomes and reduce total costs related to percutaneous coronary intervention (PCI) procedures, according to a retrospective study being presented March 26 at the 61st annual American College of Cardiology (ACC) scientific session.

27 Mar 2012

Detailed CT scan can safely and quickly rule out possibility of heart attack

A highly detailed CT scan of the heart can safely and quickly rule out the possibility of a heart attack among many patients who come to hospital emergency rooms with chest pain, according to the results of a study that will be presented by researchers from the Perelman School of Medicine at the University of Pennsylvania today at the American College of Cardiology's 61st Annual Scientific Session and published concurrently in the New England Journal of Medicine.

27 Mar 2012

Catheter-based heart valve procedures effective for patients with aortic stenosis

Patients diagnosed with aortic stenosis who are too sick for open-heart surgery have better survival rates and an improved quality of life after undergoing catheter-based heart valve replacement than if the patients had been treated with standard medical therapy, according to a study authored by a Cedars-Sinai Heart Institute physician based on results from a multicenter clinical trial.

27 Mar 2012

Simple placebo pill can track footprints of prior antidepressant use

Individuals with major depressive disorder (MDD) often undergo multiple courses of antidepressant treatment during their lives. This is because the disorder can recur despite treatment and because finding the right medication for a specific individual can take time.

27 Mar 2012

Minimally invasive treatments re-establish blood flow in people with chronic DVT

Interventional radiology treatments re-establish blood flow in people with chronic deep vein thrombosis (DVT), reducing disabling symptoms and improving the quality of life for those afflicted with post-thrombotic syndrome—an under-recognized but frequent long-term complication of DVT.

27 Mar 2012

Pacemaker may effectively prevent NMS-related fainting spells

A select number of patients who suffer from neurally mediated synope (NMS) - a disorder in which the brain fails to regulate heart rate and blood pressure - may be good candidates to receive a dual-chamber pacemaker to prevent common NMS-related fainting spells, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

Rivaroxaban safer, effective than standard therapy in treating PE

A novel oral anti-coagulant outperformed the injected standard therapy on important safety measures for initial and long-term treatment of pulmonary embolism - a blockage of lung blood vessels usually caused by a clot - and showed comparable efficacy, according to data from the EINSTEIN-PE trial presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

Bariatric surgery effectively controls diabetes

Overweight, diabetic patients who underwent bariatric surgery achieved significant improvement or remission of their diabetes, according to new research from Cleveland Clinic.

27 Mar 2012

New technique can detect small secondary brain tumours

Cancer Research UK scientists have developed a technique they believe could be used to detect tiny secondary tumours in the brain, a process that is currently impossible, according to research published in PNAS.

27 Mar 2012

GE Healthcare, DiaGenic enter research collaboration to develop blood-based test for MCI

DiaGenic ASA today announced a research agreement to collaborate with GE Healthcare to develop a blood-based test using DiaGenic's peripheral gene expression profiling in patients with mild cognitive impairment, a disorder associated with risk for Alzheimer's Disease.

27 Mar 2012

Intravenous immune globulin effective treatment for GBS, CIDP

Intravenous immune globulin (IVIg) is an effective treatment for certain disorders of the nerve and muscles, including Guillain-Barré syndrome (GBS) and a form of neuropathy called chronic inflammatory demyelinating polyneuropathy (CIDP), according to a guideline issued by the American Academy of Neurology.

27 Mar 2012

CCTA can safely and rapidly identify candidates for discharge from EDs

Coronary CT angiography (CCTA) -- a non-invasive way to look inside arteries that supply blood to the heart -- can quickly and reliably determine which patients complaining of chest pain at an emergency department can safely be sent home, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

SAR236553/REGN727 antibody reduces LDL by up to 72% in patients

A novel monoclonal antibody identified in a new study dramatically lowered circulating LDL cholesterol by 40 percent to 72 percent, a development with potential to provide a new option for patients who are resistant to cholesterol-lowering drugs such as statins or to the current standard of care, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

Medtronic pacemaker reduces risk of syncope recurrence

Medtronic, Inc. today announced the results of a double-blind, randomized study, ISSUE-3, which found that patients who suffered from fainting due to neurocardiogenic syncope had fewer fainting occurrences when treated with a Medtronic pacemaker.

From Medtronic 27 Mar 2012

Study clarifies conflicting reports for clot aspiration and abciximab administration

The anti-platelet drug abciximab, delivered directly to lesions caused by a heart attack, significantly decreased damage to the heart muscle in high-risk patients while clot aspiration showed no impact, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

From Medtronic 27 Mar 2012

Bariatric surgery better than standard medical treatment for severe type 2 diabetes

In the first published study of its kind, researchers from the Catholic University/Policlinico Gemelli in Rome, Italy, and NewYork-Presbyterian/Weill Cornell Medical Center found that bariatric surgery dramatically outperforms standard medical treatment of severe type 2 diabetes.

27 Mar 2012

Simple OB/GYN screening may identify risk of heart disease among women

Simple screening implemented in obstetrics and gynecology (OB/GYN) clinics may identify previously undetected heart disease risk among women and has the potential to greatly increase education about prevention and treatment of cardiovascular disease in female patients, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

Novel interventional radiology procedure zaps around complicated pancreatic tumors

Results of a study presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif., signal a light at the end of the tunnel for individuals with inoperable locally advanced pancreatic cancer (LAPC). A new procedure called irreversible electroporation or IRE uses microsecond electrical pulses to force open and destroy tumor cells around a vast and delicate network of blood vessels of the pancreas.

27 Mar 2012

Blood News and Research

Previously unknown mechanism helps intestinal bacteria to affect formation of blood vessels

Study reveals clinically relevant differences between on pump and off pump bypass

High-risk, high-cost PCI patients can be identified through pre-procedure bleeding risk score

Detailed CT scan can safely and quickly rule out possibility of heart attack

Catheter-based heart valve procedures effective for patients with aortic stenosis

Simple placebo pill can track footprints of prior antidepressant use

Minimally invasive treatments re-establish blood flow in people with chronic DVT

Pacemaker may effectively prevent NMS-related fainting spells

Rivaroxaban safer, effective than standard therapy in treating PE

Bariatric surgery effectively controls diabetes

New technique can detect small secondary brain tumours

GE Healthcare, DiaGenic enter research collaboration to develop blood-based test for MCI

Intravenous immune globulin effective treatment for GBS, CIDP

CCTA can safely and rapidly identify candidates for discharge from EDs

SAR236553/REGN727 antibody reduces LDL by up to 72% in patients

Medtronic pacemaker reduces risk of syncope recurrence

Study clarifies conflicting reports for clot aspiration and abciximab administration

Bariatric surgery better than standard medical treatment for severe type 2 diabetes

Simple OB/GYN screening may identify risk of heart disease among women

Novel interventional radiology procedure zaps around complicated pancreatic tumors

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