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Study suggesting that CRISPR babies are likely to die early has been retracted

A research paper that sparked concerns about the lifespan of China's first gene-edited babies has been retracted due to technical errors.

15 Oct 2019

How Is Ophthalmology Changing To Meet New Challenges?

Ophthalmology, a highly dynamic space in vision loss and age-related eye diseases with approximately 1.3 billion people living with vision impairment.

From Santen Pharmaceutical Co., Ltd. 15 Oct 2019

Risk of genetic seizure disorder: new scoring system

A Cleveland Clinic-led initiative has come up with a new risk scoring system for epileptic or seizure disorders of genetic origin. The researchers summed up the risks for a very large number of genes weakly implicated in some common forms of epilepsy, to create a polygenic risk score.

14 Oct 2019

Custom-made oligonucleotide therapy for girl with fatal Batten disease

Sufferers of fatal Batten disease have been given new hope as scientists develop a custom-made oligonucleotide therapy for a young girl.

14 Oct 2019

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

In continuing efforts to find novel ways to kill cancer cells, researchers at the University of Maryland School of Medicine have identified a new pathway that leads to the destruction of cancer cells.

14 Oct 2019

New genomics technique can be used to track down the causes of rare genetic diseases

A team led by a scientist at Scripps Research has invented a new genomics technique for tracking down the causes of rare genetic diseases.

11 Oct 2019

Understanding protein aggregation over time can help decipher early stages of Parkinson's

One of the biggest difficulties in treating Parkinson's disease, a progressive neurodegenerative disorder, is the understanding of when it starts.

11 Oct 2019

Combination drug appears to improve lung health in patients with cystic fibrosis, but with caveats

In adolescent and adult patients with cystic fibrosis taking lumacaftor-ivacaftor (ORKAMBI), the combination drug appears to improve lung function and body weight and reduce the need for intravenous antibiotic treatment, according to a French study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

11 Oct 2019

New study finds genetic link for some forms of SIDS

A genetic link has now been found for some instances of Sudden Infant Death Syndrome, or SIDS. The new UW Medicine research study is the first to make an explainable link tracking the mechanism between a genetic anomaly and some forms of the devastating syndrome, which claims the lives of more than 3,000 infants a year.

11 Oct 2019

Researchers develop customized drug treatment to bypass patient’s unique mutation

An unprecedented case at Boston Children's Hospital shows that it's possible to do something that's never been done before: identify a patient's unique mutation, design a customized drug to bypass it, manufacture and test the drug, and obtain permission from the Food and Drug Administration (FDA) to begin treating the patient -- all in less than one year.

11 Oct 2019

Genetic mechanisms could serve as a road map for screening new drugs to prolong healthy lifespan

The discovery in the 1990s that a mutation in a single gene of an experimental worm could double its lifespan set off a stampede of research on the molecular biology of aging and triggered hopes that drug therapies or other interventions could be developed to extend healthy human lifespan. But as is often the case in science, the genetic regulation of aging is more complicated than it first appeared.

10 Oct 2019

Study pinpoints a gene that allows chlamydia to pick up DNA from host environment

According to the Centers for Disease Control and Prevention, chlamydia trachomatis is the most commonly reported sexually transmitted bacterial disease in the U.S., totaling 1.7 million cases in 2017. Rates are highest among teenagers and young adults. Left untreated, chlamydia can cause blindness and sterility.

10 Oct 2019

TSC1 status may predict response to Hsp90 inhibitors in bladder cancer patients

The researchers have recently identified the tumor suppressor tuberous sclerosis complex 1 as a new co-chaperone of Hsp90 that affects Hsp90 binding to its inhibitors.

10 Oct 2019

Kazan University researchers study the genetics of nephropathia epidemica

This particular inquiry pertains to CCR5 - a gene which has lately been on the focuses of research worldwide. In particular, CCR5 deletion was used in China to perform the first ever genetic editing on human embryos. It's also known that a CCR5-Δ32 mutation can make people immune to HIV.

10 Oct 2019

Researchers identify genetic mutation that causes idiopathic pulmonary fibrosis

Researchers in Japan have identified a genetic mutation that causes a severe lung disease called idiopathic pulmonary fibrosis by killing the cells lining the lung's airways.

10 Oct 2019

New algorithm hand-picks which cancer mutations are promising targets for immunotherapy

As tumor cells multiply, they often spawn tens of thousands of genetic mutations. Figuring out which ones are the most promising to target with immunotherapy is like finding a few needles in a haystack.

9 Oct 2019

Novel cancer-driving mutation discovered in vast non-coding regions of the cancer genome

An Ontario-led research group has discovered a novel cancer-driving mutation in the vast non-coding regions of the human cancer genome, also known as the "dark matter" of human cancer DNA.

9 Oct 2019

Cedars-Sinai breast radiologist explains benefits of 3D mammography for every woman

If it's October, it's Breast Cancer Awareness Month, when pink ribbons sprout up on everything from suit lapels to yogurt containers, reminding women to turn their attention to breast health -- especially mammograms.

9 Oct 2019

Scientists discover new patterns in the evolution of the influenza virus

Researchers from Skoltech have found that the devious influenza virus is capable of new patterns of evolution and mutation in order to escape treatment with the currently available drugs and prevention with the currently available vaccines. This discovery however could help researchers predict the potential mutations in the genome of the virus and ultimately help them develop and design more effective vaccines against influenza.

9 Oct 2019

New grants support research on mechanics of tumor cells

At the cellular level, cancer can be viewed as a mechanical engineering challenge. The disease alters the structure and function of cells and tissues, which are meant to perform very specific tasks.

8 Oct 2019

Mutation News and Research

Study suggesting that CRISPR babies are likely to die early has been retracted

How Is Ophthalmology Changing To Meet New Challenges?

Risk of genetic seizure disorder: new scoring system

Custom-made oligonucleotide therapy for girl with fatal Batten disease

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

New genomics technique can be used to track down the causes of rare genetic diseases

Understanding protein aggregation over time can help decipher early stages of Parkinson's

Combination drug appears to improve lung health in patients with cystic fibrosis, but with caveats

New study finds genetic link for some forms of SIDS

Researchers develop customized drug treatment to bypass patient’s unique mutation

Genetic mechanisms could serve as a road map for screening new drugs to prolong healthy lifespan

Study pinpoints a gene that allows chlamydia to pick up DNA from host environment

TSC1 status may predict response to Hsp90 inhibitors in bladder cancer patients

Kazan University researchers study the genetics of nephropathia epidemica

Researchers identify genetic mutation that causes idiopathic pulmonary fibrosis

New algorithm hand-picks which cancer mutations are promising targets for immunotherapy

Novel cancer-driving mutation discovered in vast non-coding regions of the cancer genome

Cedars-Sinai breast radiologist explains benefits of 3D mammography for every woman

Scientists discover new patterns in the evolution of the influenza virus

New grants support research on mechanics of tumor cells

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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