Therapeutics News and Research

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A review of drugs harmful in COVID-19

In a new study, researchers investigate a number of drugs that are believed to potentially worsen outcomes in patients with COVID-19.

26 Sep 2021

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

Twist Bioscience Corporation (Nasdaq: TWST) today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19.

25 Sep 2021

MD Anderson supports World Cancer Research Day and its efforts to promote cancer research

The University of Texas MD Anderson Cancer Center is proud to support World Cancer Research Day, Sept. 24, and its efforts to promote cancer research as a driving force behind progress in cancer prevention, early detection, treatment, and survivorship.

25 Sep 2021

Researchers receive $3.7 million grant to diagnose and treat concussion-related eye disorder

Nearly half of adolescents and young adults with lingering symptoms of concussion suffer from an eye coordination disorder that causes blurred and double vision, headaches and difficulties concentrating. There is no proven method for treating the condition when it occurs after a head injury.

24 Sep 2021

Research reveals underperformance of many Phase III oncology trials

New research in the September 2021 issue of JNCCN - Journal of the National Comprehensive Cancer Network finds that more than 80% of therapies tested in Phase III oncology trials did not achieve meaningful clinical benefit in prolonging survival.

24 Sep 2021

Scientists publish a detailed map of where human antibodies bind to SARS-CoV-2

Scientists at La Jolla Institute for Immunology (LJI) have published a detailed map of where human antibodies bind to SARS-CoV-2, a map that was generated by a global collaboration comparing nearly all leading clinical candidates.

24 Sep 2021

Study identifies master regulator behind the development of antibody-producing cells

The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system and may help understand how tissues develop and how certain cancers arise.

24 Sep 2021

Researchers discover how Rift Valley fever virus enters cells

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle.

24 Sep 2021

Design of mRNA vaccines to combat COVID-19

A recent review study discusses fundamental concepts in the successful delivery of nucleic acids in therapeutics.

23 Sep 2021

Altered characteristics of granulocytes in COVID-19 patients can be linked to disease severity

COVID-19 disease severity seems to be affected by the characteristics of white blood cells called granulocytes, which are part of the innate immune system.

23 Sep 2021

Scientists discover how mucus protein emerges to disrupt airways of individuals with lung conditions

Mucus is an essential protective layer of gel-like liquid composed largely of proteins called mucins throughout our airways. One of them, called MUC5B, is crucial for the innate defense against the various things we inhale.

23 Sep 2021

Neuroscientists discover how associative memories are formed

Has the scent of freshly baked chocolate chip cookies ever taken you back to afternoons at your grandmother's house? Has an old song ever brought back memories of a first date? The ability to remember relationships between unrelated items (an odor and a location, a song and an event) is known as associative memory.

23 Sep 2021

Increased signaling by sonic hedgehog protein can inhibit LID in Parkinson's patients

Levodopa, or L-dopa, is considered the most effective treatment for Parkinson's disease today. After a few years of treatment, however, almost all patients develop a debilitating side-effect called L-dopa induced dyskinesia, or LID, which causes involuntary movements in the limbs, face, and torso. Deep brain stimulation can alleviate LID, but the procedure is highly invasive and not all patients are eligible.

23 Sep 2021

Researchers unravel the structure of bacterial appendages

A research team led by David Thanassi, PhD, of Stony Brook University, has used molecular biology and cryoelectron microscopy to successfully unravel the structure of bacterial appendages called P pili.

22 Sep 2021

Remote diabetes management using CGM and telemedicine visits can improve glycemic control

New case studies show the benefits of remote management based on continuous glucose monitoring (CGM) and telemedicine visits for patients with type 1 and type 2 diabetes during the COVID-19 pandemic.

22 Sep 2021

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

Penn Medicine and The Wistar Institute have been awarded a prestigious $11.7 million Specialized Programs of Research Excellence, or SPORE, grant from the National Cancer Institute.

22 Sep 2021

COVID-19 vaccination in IBD patients

In this review, researchers reviewed all published research related to Phase 1/2 and/or Phase 3 and 4 studies of SARS-CoV-2 vaccinations.

22 Sep 2021

PerkinElmer Completes Acquisition of Antibody and Reagent Leader BioLegend

PerkinElmer today announced it has completed its acquisition of BioLegend, a leading, worldwide provider of life science antibodies and reagents.

From Revvity 22 Sep 2021

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Sep 2021

Discovery of genes opens the door to new treatments for obesity

Promising news in the effort to develop drugs to treat obesity: University of Virginia scientists have identified 14 genes that can cause and three that can prevent weight gain.

22 Sep 2021

Therapeutics News and Research

A review of drugs harmful in COVID-19

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

MD Anderson supports World Cancer Research Day and its efforts to promote cancer research

Researchers receive $3.7 million grant to diagnose and treat concussion-related eye disorder

Research reveals underperformance of many Phase III oncology trials

Scientists publish a detailed map of where human antibodies bind to SARS-CoV-2

Study identifies master regulator behind the development of antibody-producing cells

Researchers discover how Rift Valley fever virus enters cells

Design of mRNA vaccines to combat COVID-19

Altered characteristics of granulocytes in COVID-19 patients can be linked to disease severity

Scientists discover how mucus protein emerges to disrupt airways of individuals with lung conditions

Neuroscientists discover how associative memories are formed

Increased signaling by sonic hedgehog protein can inhibit LID in Parkinson's patients

Researchers unravel the structure of bacterial appendages

Remote diabetes management using CGM and telemedicine visits can improve glycemic control

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

COVID-19 vaccination in IBD patients

PerkinElmer Completes Acquisition of Antibody and Reagent Leader BioLegend

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Discovery of genes opens the door to new treatments for obesity

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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