B Cell News and Research

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Obesity-driven estrone emerges as a key driver of deadly postmenopausal breast cancer

A new analysis of research into the most common type of breast cancer has zeroed in on an overlooked hormone that may be responsible for the increased risk of breast cancer death in post-menopausal women with obesity.

2 Dec 2025

Cell nucleus shape plays a key role in cancer therapy outcomes

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden.

2 Dec 2025

How tick saliva reprograms the skin’s immune defenses

A research team led by the Medical University of Vienna has gained new insights into how ticks influence the human immune system in order to introduce pathogens.

2 Dec 2025

AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects

One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through changes in protein expression.

2 Dec 2025

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Discover how electron microscopy advances plant and microbial research with expert insights from the John Innes Centre’s bioimaging facility.

From Leica Microsystems GmbH 2 Dec 2025

New technique overcomes technological barrier in 3D brain imaging

Scientists at the Swiss Light Source SLS have succeeded in mapping a piece of brain tissue in 3D at unprecedented resolution using X-rays, non-destructively. The breakthrough overcomes a long-standing technological barrier that had limited the use of X-rays for such studies.

2 Dec 2025

Atelerix and Labskin partner to enable long-distance transport of advanced in vitro skin models

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced an agreement with Labskin, a global leader in laboratory-grown human skin models used for research, testing and product development.

2 Dec 2025

Study provides new hope for future treatment of intestinal condition IBS

Researchers at örebro University in Sweden have made a significant advance in understanding the intestinal condition IBS.

2 Dec 2025

Specific DNA sequences control spinal cord injury response

After a spinal cord injury, cells in the brain and spinal cord change to cope with stress and repair tissue. A new study from Karolinska Institutet, published in Nature Neuroscience, shows that this response is controlled by specific DNA sequences.

2 Dec 2025

Generative AI aids discovery of ISM3830's novel scaffold

Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative regulator of T‑cell and natural killer (NK) cell activation, playing a central role in modulating T-cell activation and immune tolerance, and its inhibition enhances T cells and NK cells function, also provides a strategy for the function restoration of exhausted T cells.

1 Dec 2025

New technique helps understand how bacterial shapes contribute to disease

Scientists have long known that bacteria come in many shapes and sizes, but understanding what those differences mean has remained a major challenge, especially for species that can't be grown in the lab. Now, a new study led by Nina Wale, an Assistant Professor in MSU's Department of Microbiology, Genetics, & Immunology, introduces a groundbreaking method that could change how researchers study bacterial diversity.

1 Dec 2025

Neural stem cells drive lifelong eye growth in marine bristleworms

A new study, led by the University of Vienna and the Alfred Wegener Institute in Bremerhaven, shows how the eyes of adult marine bristleworms continue to grow throughout life – driven by a ring of neural stem cells reminiscent of vertebrate eyes.

1 Dec 2025

Innate immunity and metabolic stress drive a unique form of cell death

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together.

1 Dec 2025

Killer T cell traits explain why some people achieve long-term HIV remission after treatment

Researchers led by a team from Mass General Brigham and the Ragon Institute have discovered why some people living with HIV who are given a treatment called broadly neutralizing anti-HIV antibodies (bNAbs) can safely stop taking standard, lifelong HIV medications and maintain control of the virus for years, while others given the same treatment do not achieve this remission.

1 Dec 2025

Study links endocrine-disrupting chemicals to hidradenitis suppurativa

A Johns Hopkins Medicine study involving a dozen people with the inflammatory skin disease hidradenitis suppurativa (HS), which mostly affects skin folds, is believed to be the first to provide evidence that hormone-disrupting chemicals commonly found in ultra-processed food and single-use water bottles may contribute to the development of or worsen the condition in some people.

1 Dec 2025

Researchers uncover GFAP’s role in mitochondrial dysfunction

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare.

1 Dec 2025

Study reveals ATM kinase as the key driver of replicative senescence

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective caps at the chromosome ends-those caps eventually become too short to prevent chromosome ends from being recognized as DNA breaks.

1 Dec 2025

UTEP scientists find promising new target in the fight against high-grade serous carcinoma

Scientists at The University of Texas at El Paso have found a promising new target in the fight against high-grade serous carcinoma, an aggressive form of ovarian cancer.

1 Dec 2025

Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy.

1 Dec 2025

Machine learning tool identifies compounds that induce cancer cells into senescence

A new research paper featured on the cover of Volume 17, Issue 11 of Aging-US was published on October 30, 2025, titled "SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells."

1 Dec 2025

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B Cell News and Research

Obesity-driven estrone emerges as a key driver of deadly postmenopausal breast cancer

Cell nucleus shape plays a key role in cancer therapy outcomes

How tick saliva reprograms the skin’s immune defenses

AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

New technique overcomes technological barrier in 3D brain imaging

Atelerix and Labskin partner to enable long-distance transport of advanced in vitro skin models

Study provides new hope for future treatment of intestinal condition IBS

Specific DNA sequences control spinal cord injury response

Generative AI aids discovery of ISM3830's novel scaffold

New technique helps understand how bacterial shapes contribute to disease

Neural stem cells drive lifelong eye growth in marine bristleworms

Innate immunity and metabolic stress drive a unique form of cell death

Killer T cell traits explain why some people achieve long-term HIV remission after treatment

Study links endocrine-disrupting chemicals to hidradenitis suppurativa

Researchers uncover GFAP’s role in mitochondrial dysfunction

Study reveals ATM kinase as the key driver of replicative senescence

UTEP scientists find promising new target in the fight against high-grade serous carcinoma

Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients

Machine learning tool identifies compounds that induce cancer cells into senescence

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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