Biochemistry News and Research

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Study: Witnessing trauma triggers unique brain changes

For years, post-traumatic stress disorder (PTSD) has been studied primarily in people who experience trauma firsthand.

18 Mar 2025

New insights into ADAR1 mechanisms could revolutionize autoimmune and cancer therapies

A research team led by Rice University's Yang Gao has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses.

17 Mar 2025

Researchers develop new compound to treat alopecia areata

A research group, led by Dr. Pavel Majer from IOCB Prague, in collaboration with the laboratories of Barbara Slusher and Louis Garza at Johns Hopkins University, have developed a compound that could potentially treat the autoimmune disorder alopecia areata, which causes hair loss leading to the formation of bald patches.

13 Mar 2025

Shift Biosciences announces key appointments to advance rejuvenation therapeutics pipeline

Shift Biosciences, a biotech company using an AI powered virtual cell to fight age-related diseases, today announced the appointments of Jill Reckless, Ph.D, as Translation Advisor and Laurence Reid, Ph.D., as Non-Executive Director. In these roles, Jill and Laurence will guide Shift in building a robust product translation and business development strategy respectively, enabling the Company to capitalize on early momentum and progress its pipeline of novel rejuvenation therapeutics towards clinical development.

12 Mar 2025

Study reveals how silent X chromosome enhances female brain resilience

In a surprise, work in mice has found that the dormant X chromosome in females can reawaken late in life and turn on genes that keep the brain healthy.

6 Mar 2025

Circadian clocks influence muscle recovery

The body's internal clock doesn't just dictate when we sleep - it also determines how quickly our muscles heal.

6 Mar 2025

New drug candidate may help combat metabolic dysfunction-associated steatotic liver disease

A study published in Nature Aging has revealed a promising new drug candidate that may help combat metabolic dysfunction-associated steatotic liver disease (MASLD), a chronic liver condition that disproportionately affects communities in San Antonio due to high rates of obesity and diabetes.

5 Mar 2025

Researchers uncover key biological mechanism that prevents sperm-egg fusion

A Yale-led research team has uncovered how a naturally occurring biological mechanism found in mammals is able to prevent sperm cells from interacting with an egg, preventing fertilization.

3 Mar 2025

Synthetic microbiome therapy offers new hope against C. difficile infections

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

3 Mar 2025

Breakthrough research uncovers way to maintain metabolism during calorie restriction

Many people who have tried to lose weight by cutting calories are familiar with this frustrating reality: at some point, the body stops shedding pounds.

3 Mar 2025

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

3 Mar 2025

Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

3 Mar 2025

Study identifies key role of JMJD1C in acute myeloid leukemia

Acute myeloid leukemia (AML) is one of the most aggressive and genetically complex cancers, marked by the unchecked growth of immature myeloid cells.

3 Mar 2025

Stress granules as potential biomarkers for neurodegenerative diseases

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

3 Mar 2025

Skin organoids show promise for treating frostbite injuries

Frostbite is a severe cold injury that affects millions worldwide, often resulting in prolonged recovery, scarring, and long-term complications such as chronic pain and dysfunction.

3 Mar 2025

Macrophages use bacteria to build vital nutrients and control inflammation

Immune cells that eat bacteria in the body don't stash them in specialized compartments as once thought, but turn them into critical nutrients that build proteins, create energy and keep the cells alive, according to a new study from scientists at the University of Colorado Anschutz Medical Campus.

27 Feb 2025

Retinal changes may serve as early indicator for Alzheimer's disease

A team of scientists at the Indiana University School of Medicine has identified that an eye condition affecting the retina, the light-sensing tissue in the back of the eye, may serve as an early indicator for Alzheimer's disease.

26 Feb 2025

New protein identified as key to protecting kidneys in diabetic nephropathy

This study is led by Dr. Haisheng Zhou (Department of Biochemistry and Molecular Biology, Anhui Medical University, China) and Dr. Guoling Zhou (Center for Computational Integrative Biology, Massachusetts General Hospital, USA).

24 Feb 2025

Discovery paves way for new hepatitis B treatment

In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, research led by Memorial Sloan Kettering Cancer Center (MSK), Weill Cornell Medicine, and The Rockefeller University identified a vulnerability that opens the door to new treatments.

22 Feb 2025

New human antibody shows promise for Ebola virus treatment

New research led by scientists at La Jolla Institute for Immunology (LJI) reveals the workings of a human antibody called mAb 3A6, which may prove to be an important component for Ebola virus therapeutics.

21 Feb 2025

Biochemistry News and Research

Study: Witnessing trauma triggers unique brain changes

New insights into ADAR1 mechanisms could revolutionize autoimmune and cancer therapies

Researchers develop new compound to treat alopecia areata

Shift Biosciences announces key appointments to advance rejuvenation therapeutics pipeline

Study reveals how silent X chromosome enhances female brain resilience

Circadian clocks influence muscle recovery

New drug candidate may help combat metabolic dysfunction-associated steatotic liver disease

Researchers uncover key biological mechanism that prevents sperm-egg fusion

Synthetic microbiome therapy offers new hope against C. difficile infections

Breakthrough research uncovers way to maintain metabolism during calorie restriction

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Study identifies key role of JMJD1C in acute myeloid leukemia

Stress granules as potential biomarkers for neurodegenerative diseases

Skin organoids show promise for treating frostbite injuries

Macrophages use bacteria to build vital nutrients and control inflammation

Retinal changes may serve as early indicator for Alzheimer's disease

New protein identified as key to protecting kidneys in diabetic nephropathy

Discovery paves way for new hepatitis B treatment

New human antibody shows promise for Ebola virus treatment

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