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One letter DNA change switches sex development in mice

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development in mice.

9 Apr 2026

Genetic variants may help explain who loses more weight and who gets side effects on GLP-1 drugs

A large 23andMe-based GWAS found that common variants in GLP1R and GIPR help explain why some people lose more weight or experience more nausea and vomiting on GLP-1 drugs. The findings suggest genetics may eventually help predict who responds best to semaglutide or tirzepatide and who is more likely to develop side effects.

9 Apr 2026

AI-powered chemistry accelerates discovery of selective cancer inhibitors

Recently, the Insilico team's research entitled "An Internal Sulfur-Lone Pair Interaction Enabled the Discovery of Potential and Sub-Family Selective PKMYT1 Inhibitors" was invited for publication as a cover Feature in ChemMedChem.

9 Apr 2026

Dynamic binding of linker histone H1 shapes flexible chromatin organization

DNA inside the nucleus is not packed as a rigid regular fiber-linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a dynamic, fluid organization that can still support essential genome functions.

9 Apr 2026

Scientists find new genetic causes for diabetes in babies

Scientists have found new genetic causes for diabetes in babies – in a part of the genome that has historically been overlooked in genetic studies.

9 Apr 2026

New method reveals how the genome is regulated and disrupted in diseases

Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like cancer.

8 Apr 2026

Study finds genetic basis for GLP-1 weight loss efficacy and side effects

23andMe Research Institute, a nonprofit medical research organization, announced the publication of a study that identifies genetic predictors for GLP-1 weight loss efficacy and side effects.

8 Apr 2026

Clusterin inhibition offers new hope for treating cervical gastric-type adenocarcinoma

Gastric-type adenocarcinoma (GAS) is one of the most aggressive non-human papillomavirus (HPV)-associated cervical adenocarcinomas and remains especially difficult to diagnose and treat.

8 Apr 2026

Study reveals how hyperdiploidy creates rare pre-leukemic clones in children

B-cell acute lymphoblastic leukemia is the most common form of childhood cancer. In this type of cancer, which affects blood cells, one of the most common abnormalities is the presence of cells with an excess of chromosomes (hyperdiploidy), a condition that leads to chromosomal instability.

8 Apr 2026

CIPHER-seq technology reveals how immune cells communicate during treatment

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

8 Apr 2026

Early genetic signals connect diabetes subgroups to heart disease risk

A growing body of research shows that diabetes can be stratified into five different subgroups. Researchers at Lund University have now investigated whether a person's genetic predisposition to different diabetes subgroups can help assess the risk of developing coronary artery disease.

7 Apr 2026

New blood test spots four cancers and other diseases by stripping away healthy DNA noise

MethylScan is a new low-cost cell-free DNA methylome test that removes much of the healthy blood DNA background, helping rare disease signals stand out more clearly. In more than 1,000 people, it showed strong performance for detecting four cancers, classifying liver diseases, and identifying organ-specific damage.

7 Apr 2026

Pol theta enzyme identified as key driver of cancer resilience

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential than researchers realized.

7 Apr 2026

Interpretable machine learning model advances analysis of complex genetic traits

A new study published in Genome Research presents an interpretable artificial intelligence framework that improves both the accuracy and transparency of genomic prediction, a key challenge in fields such as precision medicine, crop science, and animal breeding.

7 Apr 2026

World Health Day 2026: WHO urges global collaboration and science for better health

The World Health Organization (WHO) today calls on people everywhere to renew their commitment to working together and supporting science as the twin engines driving better health, under the World Health Day 2026 theme: "Together for health. Stand with science."

6 Apr 2026

AI helps researchers find antimicrobial peptides in Earth’s harshest habitats

Researchers built the Extreme Environment Microbiome Catalog from 78,213 genomes across global extreme habitats, revealing major taxonomic and biosynthetic novelty, including 32,715 representative species, nearly 4 billion non-redundant genes, and 163,693 biosynthetic gene clusters. They then used protein language models to identify 3,032 candidate non-toxic antimicrobial peptides, with 84 of 100 synthesized peptides showing antibacterial activity and low cytotoxicity in the 50 tested in mammalian cells.

6 Apr 2026