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Immune responses against SARS-CoV-2 Delta variant after BNT162b2 vaccination in people living with HIV

Researchers from Sorbonne Universite have been investigating the effect of the BNT162b2 mRNA vaccine on HIV-positive individuals.

9 Dec 2021

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

In a recent study conducted at Yale University, USA, scientists have investigated the immunogenicity of mRNA-based coronavirus disease 2019 (COVID-19) vaccine candidates encoding the spike proteins of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The findings reveal that the vaccines induce robust immune responses against SARS-CoV-2 variants. The study is currently available on the bioRxiv* preprint server.

6 Dec 2021

New marker could lead to better diagnoses of Covid-19

Biomedical scientists at LMU have found a new marker in the blood of Covid-19 patients. It furnishes insights into the course and development of the disease and could lead to better diagnoses.

6 Dec 2021

New approach to COVID-19 immune profiling using blood-based machine learning

A new study discusses the application of a novel deconvolution model AImmune to predict moderate and severe cases of COVID-19.

5 Dec 2021

Exposure to Chikungunya may offer partial cross-protection against Mayaro virus

A study conducted at the University of São Paulo (USP) in Brazil suggests people previously infected by Chikungunya virus may develop partial immunity to Mayaro virus.

4 Dec 2021

NEI researchers identify unique population of B cells that tamps down the immune system

Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation.

2 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

Study shows vaccinated multiple myeloma patients at greater risk of breakthrough SARS-CoV-2 infections

Researchers recently published a study assessing the risks of patients with MM to breakthrough infections after completing their vaccination schedule compared to those without any form of cancer.

25 Nov 2021

Study compares immune responses of patients with and without kidney failure after COVID-19 vaccination

Death rates from COVID-19 are especially high in individuals with kidney failure who are on dialysis, making SARS-CoV-2 vaccination in this population a high priority.

24 Nov 2021

Vaccine-induced immune responses for SARS-CoV-2 in patients receiving anti-CD20 B-cell depleting therapies

A new study published on the medRxiv* preprint server analyzed the trajectories of anti-SARS-CoV-2 antibodies in patients from the RituxiVac study were compared to healthy volunteers. In addition, they investigated the immunogenicity of a third vaccine dose in previously non-responding patients.

23 Nov 2021

Severe COVID-19 patients have significantly higher NK and T cell frequency

A new study published in the open-access journal Cells aimed to clarify the role of NK and T cell subsets in SARS-CoV-2 infection in hospitalized COVID-19 patients to unravel their potential association with disease severity.

18 Nov 2021

Study: Covid-19 vaccine-elicited immune cells persist six months after vaccination

A recent study by Johns Hopkins Medicine researchers provides evidence that CD4+ T lymphocytes — immune system cells also known as helper T cells — produced by people who received either of the two available messenger RNA (mRNA) vaccines for COVID-19 persist six months after vaccination at only slightly reduced levels from two weeks after vaccination and are at significantly higher levels than for those who are unvaccinated.

16 Nov 2021

The case for vaccinating children under 12 against COVID-19

Researchers assess the need for coronavirus disease 2019 (COVID-19) vaccination in children who are 12 years of age or younger.

14 Nov 2021

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Despite clear directives outlined in the updated guidelines published by the American College of Rheumatology/National Psoriasis Foundation (ACR/NPF) in 2018, there is limited data regarding medication use in real-world clinical practice and patient medication preferences for the treatment of psoriatic arthritis (PsA).

9 Nov 2021

Automated method shows predictive power for COVID-19 in-hospital mortality

Researchers focussed on the S-learner strategy of estimating the conditional average treatment effect.

4 Nov 2021

Potential link between SARS-CoV-2 infection and secondary occurrence of anti-NMDAR encephalitis

Scientists explore the link between SARS-CoV-2 infection and anti-NMDAR encephalitis.

1 Nov 2021

How long does natural or vaccine-induced immunity to COVID last?

Researchers present a comprehensive assessment on SARS-CoV-2 induced immunity.

28 Oct 2021

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

One in five cancers affects blood cells and lymph nodes, causing leukemias and lymphomas, respectively. Although their treatment with drugs has led to a great advance in their cure, there are cases where there is no clinical response or resistance to them is generated.

21 Oct 2021

Immune responses to SARS-CoV-2 infection and vaccination in patients with multiple sclerosis

A new study has focused on the immune response in pwMS undergoing anti-CD20 treatment.