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Ludwig Cancer Research study discovers new cellular oxygen sensor

A Ludwig Cancer Research study led by Peter Ratcliffe and colleagues has discovered a previously overlooked oxygen sensor in animal cells that functions very much like one used by plants.

5 Jul 2019

Study sheds light on complex caspase-1-induced cell death mechanisms

Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program.

5 Jul 2019

New biomaterial could encapsulate and protect implanted insulin-producing cells

Transplanting insulin-producing pancreatic cells into people with type 1 diabetes has emerged as a ground-breaking treatment for millions of patients over the past few decades.

4 Jul 2019

Scientists identify mechanism that makes babies more likely than adults to die from sepsis

An immune mechanism that makes babies more likely than adults to die from sepsis has been identified by scientists affiliated with the Center for Research on Inflammatory Diseases in Ribeirão Preto, São Paulo State (Brazil).

4 Jul 2019

New resistance mechanism that prevent formation of blood vessels

Researchers at IDIBELL-ICO describe a new resistance mechanism to therapies that prevent the formation of blood vessels

3 Jul 2019

Brain injury found to be common among domestic violence survivors

Domestic violence survivors commonly suffer repeated blows to the head and strangulation, trauma that has lasting effects that should be widely recognized by advocates, health care providers, law enforcement and others who are in a position to help, according to the authors of a new study.

2 Jul 2019

Scientists discover a new way to kill drug-resistant parasites

Over one billion people, including 880 million children, are infected with intestinal nematode worms, such as roundworms, hookworms and tapeworms, according to the World Health Organization.

2 Jul 2019

Gene mutation discovery leads to novel treatment for patient with severe lymphatic condition

Faced with a preteen boy in pain and struggling to breathe from a severe, deteriorating rare condition, researchers at Children's Hospital of Philadelphia identified the responsible gene mutation and harnessed that knowledge to develop a novel treatment that dramatically improved the problem.

2 Jul 2019

New target identified for treatment of idiopathic pulmonary fibrosis

An article published in Experimental Biology and Medicine (Volume 244, Issue 9, June 2019) (https://journals.sagepub.com/doi/pdf/10.1177/1535370219843827) identifies a new target for the treatment of idiopathic pulmonary fibrosis.

29 Jun 2019

Researchers propose new avenue in the search for anti-obesity drugs

Effective weight-loss strategies call for eating less food, burning more calories--or ideally, both. But for the more than 90 million Americans who suffer from obesity, a disease that contributes to conditions ranging from cancer to heart disease, behavioral change is hard to accomplish or not effective enough--which is why scientists have long sought drugs that would help people shed pounds.

29 Jun 2019

Scientists suggest possible cell-based therapy for premature infants with rare lung condition

Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia, which in the most severe cases can lead to lifelong breathing problems and even death.

27 Jun 2019

How a simple MRI scan can help patients with angina

Using a simple Magnetic Resonance Imaging (MRI) scan can help doctors diagnose their patients with angina, sparing them from the invasive procedure and an overnight stay in the hospital, a new study suggests.

25 Jun 2019

Coffee may boost weight loss, concludes study

Coffee has been shown to increase the release of heat from brown fat, potentially boosting weight loss efforts.

25 Jun 2019

Researchers explore new immune checkpoint for head and neck cancer

A checkpoint may delay travelers but it can help give cancer free rein by suppressing the natural immune response that should destroy it, researchers say.

25 Jun 2019

New promising approach repairs system of blood vessels following stroke

Following a stroke, antibodies that inhibit the signaling molecule Nogo-A can help repair blood vessels in the affected brain regions.

25 Jun 2019

Blastocyst transfer linked to higher risk of preterm birth, large-for-gestational-age rates

The transfer of embryos cultured for five or six days after fertilization in IVF and ICSI has become routine in many fertility clinics.

24 Jun 2019

Exploring the heart at a depth that was previously impossible

An international team of researchers are seeking to explore the heart at a depth that was previously impossible.

24 Jun 2019

More insights into transport protein used by cancer cells

Certain cancer cells depend on exporting the metabolite lactate, which accumulates during the generation on energy. Lactate plays an important role in many biochemical and cellular processes.

21 Jun 2019

Researchers find a potential modulator in revascularization of pancreatic islets

The first cause of the loss of functionality in transplanted pancreatic islets is the low capacity to create new vessels to allow the arrival of nutrients in the cells.

20 Jun 2019

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment's cause and develop a potential and desperately needed nanoparticle-based treatment.

19 Jun 2019