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GLP-1 drugs found to lower cancer risk in diabetes patients

Research finds that GLP-1 receptor agonists significantly reduce the risk of 10 out of 13 obesity-associated cancers in type 2 diabetes patients compared to insulins, but show varied results against metformin.

8 Jul 2024

Algorithm could identify drug-resistant bacteria from microscopy images

Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time taken for a correct diagnosis, Cambridge researchers have shown.

8 Jul 2024

Non-invasive saliva test could identify children missing tetanus immunity

University of Birmingham experts are developing a non-invasive saliva test that - within 15 minutes - might identify children across the Global South missing immunity to tetanus who may also have missed out on essential vaccines.

8 Jul 2024

New tool predicts nerve damage risk from breast cancer treatment

Many women treated for breast cancer using taxanes, a type of cytostatic drug, often experience side effects in the nervous system.

8 Jul 2024

Understanding the reach of pharmaceutical promotional events in healthcare

Promotional events sponsored by the pharmaceutical industry which target health professionals responsible for prescribing medications, such as physicians and nurse practitioners, are a key component of promotional campaigns for new drugs and devices.

8 Jul 2024

Blocking IL-6 in the brain to treat cancer cachexia

Cancer is insidious. Throughout tumor progression, the disease hijacks otherwise healthy biological processes - like the body's immune response - to grow and spread.

8 Jul 2024

UQ researchers unlock crucial molecular secrets of aging in cells

University of Queensland researchers have unlocked crucial molecular secrets of aging in cells, potentially paving the way to improve quality of life as people age.

8 Jul 2024

Case Western Reserve University receives $1.5M grant for oral drug trial to prevent blindness in RP patients

There's only one U.S. Food and Drug Administration-approved therapy for an inherited retinal disease, and dozens of retinitis pigmentosa (RP) genes for which no therapy is available.

8 Jul 2024

Plant-derived substance shows promise against pulmonary hypertension

A substance derived from the plant Ardisia crenata works in a different way than existing drugs. And in doing so, it is highly effective.

8 Jul 2024

New 'band-aid' measures body biomarkers that indicate health or disease through sweat

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a 'band-aid' or plaster that measures body 'biomarkers' that can indicate health or disease through sweat, paving the way for a new non-invasive and effective way for patients to monitor their health.

8 Jul 2024

Scientists identify over 5000 high-risk cancer gene variants

Over 5,000 genetic variants that enable certain cancers to thrive have been identified by scientists, along with a potential therapeutic target to treat or even prevent these cancers from developing.

8 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, has successfully delivered the second preclinical candidate compound (PCC) in its collaboration with Fosun Pharma in June 2024, a potential innovative therapeutic using synthetic lethal strategy for the treatment of solid tumors.

5 Jul 2024

Scientists map all the possible outcomes of changes to key tumor-suppressing gene

Researchers at the Francis Crick Institute have mapped all the possible outcomes of changes to a tumor-suppressing gene called VHL, the first step in a huge research endeavor to unpick the outcomes of tens of thousands of genetic variations in genes associated with cancer.

5 Jul 2024