Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate to all those different cell fates.

15 Nov 2017

Researchers use novel computational tool to understand complex disease processes

Hypertension and heart disease arise from many contributing and interacting factors: genetics, food, and exercise, as well as problems with heart, liver, or kidney function.

14 Nov 2017

Researchers uncover link between abdominal aortic aneurysm and dysregulated tryptophan metabolism

Researchers have found a link between dysregulated tryptophan metabolism and abdominal aortic aneurysm, a life-threatening vascular disease, according to a new study led by Georgia State University.

13 Nov 2017

Absence of VEGF-A in cancer-killing T cells accelerates tumor development

Contrary to what was previously believed, the immune system's cancer-killing T cells are more effective in a tumour's anoxic environment when they have access to growth factor VEGF-A.

13 Nov 2017

Epigenetic editing in healthy breast cells can set off chain reaction for tumor initiation

Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to begin a chain reaction and become abnormal, according to research by Queen Mary University of London.

13 Nov 2017

New research sheds light on negative effects of stress on the brain

Stress can have numerous harmful effects on the mind and body, both immediately and over long periods of time. New research reveals mechanisms by which stress exacts its toll throughout the body, from the brain to the male reproductive system, and points to potential paths for reducing the negative effects of stress.

13 Nov 2017

New discovery in beta-cell pathway shows potential to improve effectiveness of diabetes drugs

Over the past 15 years, University of Alabama at Birmingham endocrinologist Anath Shalev, M.D., has unraveled a crucial biological pathway that malfunctions in diabetes.

8 Nov 2017

Roundworms may provide new clues to nicotine dependence

Researchers at the University of Michigan Life Sciences Institute found that a previously dismissed genetic mechanism may contribute to nicotine dependence, and to the withdrawal effects that can make quitting smoking so difficult.

7 Nov 2017

Stem cells could help improve blood circulation in diabetic patients with peripheral artery disease

Stem cells taken from muscle tissue could promote better blood flow in patients with diabetes who develop peripheral artery disease, a painful complication that can require surgery or lead to amputation.

7 Nov 2017

New study finds enhanced impact of drug combination for FAP patients

People with an inherited syndrome called familial adenomatous polyposis (FAP) have a 100% lifetime risk of developing colorectal cancer if they do not seek appropriate medical care.

7 Nov 2017

Drug can safely and effectively help infants with SMA gain muscle function, study shows

More than half of the babies with infantile-onset spinal muscular atrophy (SMA) who were treated with nusinersen (Spinraza) gained motor milestones, compared to none of the babies in the control group. Infants treated with the drug also had 63 percent lower risk of death.

6 Nov 2017

Research provides path to possible treatment for Fragile X Syndrome and other types of autism

In Fragile X Syndrome--the leading genetic form of intellectual disability and autism--the effects of a single defective gene ripple through a series of chemical pathways, altering signals between brain cells.

3 Nov 2017

New study shows link between gut bacteria and age-related chronic inflammation

A new study shows for the first time that gut bacteria from old mice induce age-related chronic inflammation when transplanted into young mice.

3 Nov 2017

Study solves critical piece of deafness puzzle by identifying long non-coding RNAs

A new Tel Aviv University study solves a critical piece of the puzzle of human deafness by identifying the first group of long non-coding RNAs (lncRNAs) in the auditory system.

2 Nov 2017

Studies identify key characteristics that may allow some obese people to have 'healthier' fat tissue

One little understood paradox in the study of obesity is that overweight people who break down fat at a high rate are less healthy than peers who store their fat more effectively.

1 Nov 2017

Study shows effects of prenatal BPA exposure at low levels in developing rodent brain

New research from North Carolina State University reveals that prenatal exposure to bisphenol A (BPA) at levels below those currently considered safe for humans affects gene expression related to sexual differentiation and neurodevelopment in the developing rat brain.

31 Oct 2017

NASA’s “Twins Study” explores the effects space travel has on the human body

Preliminary results from NASA’s Twins Study have revealed some of the bodily changes that occurred in an astronaught, who spent almost one year in space, compared with his twin brother, who remained on earth.

30 Oct 2017

Biogen and Ionis awarded 2017 Prix Galien USA Award for SPINRAZA

Biogen and Ionis have been awarded the prestigious 2017 Prix Galien USA Award for Best Biotechnology Product for SPINRAZA (nusinersen). The Prix Galien USA Award recognizes extraordinary achievement in scientific innovation that improves the state of human health. The award was presented at a ceremony in New York City on October 26, 2017.

30 Oct 2017

Novel laboratory model may shine light on development of pediatric high-grade glioma

Pediatric high-grade glioma is the primary cause of cancer death in children. Genesis of these tumors is believed to be driven by mutations in proteins that disrupt fundamental mechanisms governing the development of the human brain.

27 Oct 2017

Drexel researchers pinpoint new targets for treating chronic lung disease in premature infants

Researchers at Drexel University have revealed that inhibiting the micro-RNA miR-34a significantly reduces bronchopulmonary dysplasia (BPD) in mice.

27 Oct 2017

Gene Expression News and Research

Further Reading

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

Researchers use novel computational tool to understand complex disease processes

Researchers uncover link between abdominal aortic aneurysm and dysregulated tryptophan metabolism

Absence of VEGF-A in cancer-killing T cells accelerates tumor development

Epigenetic editing in healthy breast cells can set off chain reaction for tumor initiation

New research sheds light on negative effects of stress on the brain

New discovery in beta-cell pathway shows potential to improve effectiveness of diabetes drugs

Roundworms may provide new clues to nicotine dependence

Stem cells could help improve blood circulation in diabetic patients with peripheral artery disease

New study finds enhanced impact of drug combination for FAP patients

Drug can safely and effectively help infants with SMA gain muscle function, study shows

Research provides path to possible treatment for Fragile X Syndrome and other types of autism

New study shows link between gut bacteria and age-related chronic inflammation

Study solves critical piece of deafness puzzle by identifying long non-coding RNAs

Studies identify key characteristics that may allow some obese people to have 'healthier' fat tissue

Study shows effects of prenatal BPA exposure at low levels in developing rodent brain

NASA’s “Twins Study” explores the effects space travel has on the human body

Biogen and Ionis awarded 2017 Prix Galien USA Award for SPINRAZA

Novel laboratory model may shine light on development of pediatric high-grade glioma

Drexel researchers pinpoint new targets for treating chronic lung disease in premature infants

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