Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

COVID-19 vaccine effectiveness against SARS-CoV-2 variants

A commentary published in the journal Cell summarizes international data on vaccine effectiveness against new severe acute respiratory coronavirus 2 (SARS-CoV-2) variants. Evidence shows that the currently approved vaccines continue to be effective in preventing severe and symptomatic illness — even with the widely circulating Delta variant.

21 Sep 2021

New evidence confirms the efficacy of COVID-19 vaccination in cancer patients

The long-awaited confirmation of the efficacy of COVID-19 vaccination in patients with cancer has arrived, on time to be disseminated to a global audience at the annual congress of the European Society for Medical Oncology (ESMO Congress 2021), the leading professional society for medical oncology.

20 Sep 2021

A novel FACS-based approach for SARS-CoV-2 serology

A recent study discusses a simple, sensitive, and quantitative serological test based on FACS assay to evaluate antibodies against SARS-CoV-2.

20 Sep 2021

Failures and findings from randomized clinical trials in COVID-19 convalescent plasma

Researchers complete an extensive search on previously published studies to understand the efficacy of convalescent plasma in treating COVID-19.

20 Sep 2021

Hypertension in COVID-19-affected pregnancy linked to high SARS-CoV-2 load in placenta

A new study finds that hypertension following the viral infection is associated with high placental viral load in pregnant women with COVID-19.

20 Sep 2021

T cell immunity induced after mild COVID could contribute to protection against re-infection

An interesting new study finds that in both adults and children, a mild infection with the SARS-CoV-2 elicits an antigen-specific memory T-cell response.

20 Sep 2021

Atopic dermatitis may stem from poorly regulated sex hormones, study suggests

A study led by UT Southwestern dermatologists suggests that a common inflammatory skin condition may stem from poorly regulated sex hormones.

20 Sep 2021

SARS-CoV-2 antibody models describe differences between the kinetics of different antibodies

Researchers have created kinetic models of IgG and IgM anti-SARS-CoV-2 antibodies over 13.5 months following infection to understand long-lasting immunity better.

20 Sep 2021

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Researchers from the University of Southern California investigated mutations in the N-terminal and RBD domains of the spike protein.

20 Sep 2021

COVID-19 vaccine-related allergies are rare, typically mild and treatable, finds study

Allergic reactions to the new mRNA-based COVID-19 vaccines are rare, typically mild and treatable, and they should not deter people from becoming vaccinated, according to research from the Stanford University School of Medicine.

20 Sep 2021

The influence of prior seasonal coronavirus infection on disease severity in COVID-19

A new study posted to the bioRxiv* server attempted to explore anti-spike IgG responses, Fc-gamma receptor (FcγR) activation, IgG targeting of immunodominant regions, and recall responses due to seasonal hCoV infections in non-hospitalized COVID-19 patients.

20 Sep 2021

Characterizing the flexibility of SARS-CoV-2 variant of concern spike proteins

A novel protein modeling method assesses changes to the conformation of the SARS-CoV-2 spike protein that have been encountered by mutation.

19 Sep 2021

Combining antibody markers to improve serosurveillance for SARS-CoV-2

The current study found that combining N antibodies with nucleocapsid-specific IgG facilitates a better classification of SARS-CoV-2 infection.

19 Sep 2021

Study shows efficacy of mRNA vaccines against SARS-CoV-2 in individuals with obesity

A new study evaluated the antibody response against SARS-CoV-2 between individuals who were affected by abdominal obesity (AO) and those who were not,

19 Sep 2021

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

A specially designed lipid nanoparticle could deliver immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy.

18 Sep 2021

Third dose of Pfizer-BioNTech vaccine increases neutralizing antibody levels against SARS-CoV-2

A third dose of the Pfizer-BioNTech vaccine significantly increased neutralizing antibody levels against SARS-CoV-2, the virus that causes COVID-19, according to new research published in the New England Journal of Medicine.

18 Sep 2021

Novel drug combinations improve progression-free survival for patients with advanced NSCLC

New findings from a large study led by researchers at Yale Cancer Center shows the addition of the drugs oleclumab or monalizumab to durvalumab improved progression-free survival for patients with locally advanced non-small cell lung cancer (NSCLC).

18 Sep 2021

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

In contrast to intramuscular vaccines, only nasal vaccines are able to block the virus in the nose by inducing local immunity in the nasal mucosa, i.e. the portal of entry and multiplication of the virus.

18 Sep 2021

Thousands of vulnerable hospital patients set to benefit from new COVID-19 treatment

Thousands of vulnerable NHS patients in hospital due to COVID-19 are set to benefit from a ground-breaking new antibody treatment, the government has announced today (17 September 2021).

18 Sep 2021

Scientists identify new approach to overcome resistance to cancer immunotherapy

Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in the Journal for Immunotherapy of Cancer.

17 Sep 2021

Antibody News and Research

Further Reading

COVID-19 vaccine effectiveness against SARS-CoV-2 variants

New evidence confirms the efficacy of COVID-19 vaccination in cancer patients

A novel FACS-based approach for SARS-CoV-2 serology

Failures and findings from randomized clinical trials in COVID-19 convalescent plasma

Hypertension in COVID-19-affected pregnancy linked to high SARS-CoV-2 load in placenta

T cell immunity induced after mild COVID could contribute to protection against re-infection

Atopic dermatitis may stem from poorly regulated sex hormones, study suggests

SARS-CoV-2 antibody models describe differences between the kinetics of different antibodies

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

COVID-19 vaccine-related allergies are rare, typically mild and treatable, finds study

The influence of prior seasonal coronavirus infection on disease severity in COVID-19

Characterizing the flexibility of SARS-CoV-2 variant of concern spike proteins

Combining antibody markers to improve serosurveillance for SARS-CoV-2

Study shows efficacy of mRNA vaccines against SARS-CoV-2 in individuals with obesity

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

Third dose of Pfizer-BioNTech vaccine increases neutralizing antibody levels against SARS-CoV-2

Novel drug combinations improve progression-free survival for patients with advanced NSCLC

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

Thousands of vulnerable hospital patients set to benefit from new COVID-19 treatment

Scientists identify new approach to overcome resistance to cancer immunotherapy

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