Genes News and Research

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Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Researchers used a genetically engineered porcine donor to develop kidney grafts.

11 Oct 2023

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

The effect of a novel Kv7.2/Kv7.3 potassium channel opener XEN1101 in reducing monthly seizure frequency in adults.

11 Oct 2023

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Gut microbiota and macrophage-neutrophil interactions in the impact of dietary phenolic acids on intestinal inflammation.

11 Oct 2023

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

The intricate interactions between gut microbiota and drugs.

11 Oct 2023

Fragile X syndrome may be unfolding in brain cells even before birth

Fragile X syndrome, the most common form of inherited intellectual disability, may be unfolding in brain cells even before birth, despite typically going undiagnosed until age 3 or later.

10 Oct 2023

New blood test could detect ovarian cancer early, improve treatment

High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it during the cancer's early stages, when it's easiest to treat.

10 Oct 2023

Living past 100: Healthy habits, good company, and a purpose in life

Researchers explore the secrets behind increased life expectancies, focusing on the influence of diet, lifestyle, and socio-economic changes. Centenarians, individuals living past 100, often delay age-related symptoms, suggesting a lifestyle emphasizing a balanced diet, social interaction, and regular exercise can significantly boost longevity and resilience.

10 Oct 2023

Study sheds light on the role of immune cells in fat tissue inflammation and obesity

Fat tissue, for as much as it's been vilified, is an incredibly complex and essential bodily organ involved in energy storage and hormone production, among other functions.

10 Oct 2023

Study supports genetic predisposition to chronic regional pain syndrome in a third of cases

Genes may be responsible for third of complex regional pain syndrome cases. But the condition is less common in men, even though they are more likely to have the 4 genetic variations implicated in heightened risk, suggesting that there may be sex specific causes, say the researchers.

10 Oct 2023

DNA aptamers: A versatile tool for regenerative medicine and beyond

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

10 Oct 2023

Stress-induced ribosome dysregulation may underlie depression

A group of ribosomal protein genes connects animal models of depression to human patients with major depressive disorder.

10 Oct 2023

Does renting accelerate biological aging? New study sparks housing policy debate

Living in privately rented homes is linked to faster biological aging, with its impact nearly double that of unemployment. However, these effects are reversible, highlighting the potential of housing policies in health improvement.

10 Oct 2023

Neanderthal genes make some humans more pain-sensitive

People with three Neanderthal-inherited gene variants in SCN9A are more sensitive to certain types of pain, revealing past interbreeding's genetic influence on modern humans. This study, led by UCL researchers, underscores pain sensitivity as a crucial evolutionary trait potentially shaped by Neanderthal genetics.

10 Oct 2023

Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Study discovers epigenetic regulator's critical role in mitochondrial metabolism

The intricate control of cellular metabolism relies on the coordinated and harmonious interplay between the nucleus and mitochondria.

9 Oct 2023

Bio-inspired drug restores the effectiveness of immune cells in fighting cancer

A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer, a team led by researchers at The University of Texas at Austin has found.

9 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

Is your DNA steering you towards a vegetarian diet?

Researchers using the UK Biobank identified genetic markers linked to strict vegetarianism, revealing potential connections between vegetarianism, lipid metabolism, and brain activity. The study highlighted genes, particularly those active in the brain and related to cholesterol movement, as influential in an individual's inclination towards a vegetarian lifestyle.

9 Oct 2023

Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

In a study published in the journal Genes & Diseases, researchers from Army Medical University and Shenzhen University investigated the pivotal role of miR-18a-5p, a microRNA, in the development and progression of osteoblastic lesions resulting from prostate cancer (PCa) bone metastasis.

9 Oct 2023

EMC1 protein found to play pivotal role in retinal vascular development

In a groundbreaking study published in the journal Genes & Diseases, researchers from University of Electronic Science and Technology of China have uncovered a key relationship between the EMC1 protein and retinal vascular development.

9 Oct 2023

Genes News and Research

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

Fragile X syndrome may be unfolding in brain cells even before birth

New blood test could detect ovarian cancer early, improve treatment

Living past 100: Healthy habits, good company, and a purpose in life

Study sheds light on the role of immune cells in fat tissue inflammation and obesity

Study supports genetic predisposition to chronic regional pain syndrome in a third of cases

DNA aptamers: A versatile tool for regenerative medicine and beyond

Stress-induced ribosome dysregulation may underlie depression

Does renting accelerate biological aging? New study sparks housing policy debate

Neanderthal genes make some humans more pain-sensitive

Discovery of a novel therapeutic target for pancreatic cancer

Study discovers epigenetic regulator's critical role in mitochondrial metabolism

Bio-inspired drug restores the effectiveness of immune cells in fighting cancer

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

Is your DNA steering you towards a vegetarian diet?

Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

EMC1 protein found to play pivotal role in retinal vascular development

eBook: Using iPSCs models for human disease research and drug discovery eBook

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