Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

New computer program identifies different cell types based on gene expression patterns

"How many different cell types are there in a human body? And how do these differences develop? Nobody really knows," says Professor Stein Aerts from KU Leuven and VIB, Belgium. But thanks to a new method developed by his team, that may be about to change.

10 Oct 2017

Penn Medicine professor receives New Innovator Award from NIH

Hao Wu, PhD, an assistant professor of Genetics in the Perelman School of Medicine at the University of Pennsylvania has received a New Innovator Award from the National Institutes of Health. These awards provide each recipient $1.5 million over five years to pursue high-risk, high-reward investigations that could have implications for human health.

9 Oct 2017

Researchers develop new diagnostic and prognosis method for early detection of liver cancer

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood sample containing circulating tumor DNA.

9 Oct 2017

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Preeclampsia is the most dangerous form of hypertension during a pregnancy and can be fatal for both mother and child. Though it is known to originate in the placenta, the root causes remain largely a mystery.

6 Oct 2017

Researchers uncover promising targets for development of drugs against leishmaniasis

Brazilian researchers at the University of São Paulo's Bioscience Institute (IB-USP) are starting to unravel the molecular mechanisms by which the parasite that causes cutaneous leishmaniasis manages to circumvent the host organism's defenses and infect new cells.

5 Oct 2017

Study sheds light on complex process involved in development of sperm stem cells

New research from scientists at Huntsman Cancer Institute at the University of Utah and collaborators at University of Utah Health sheds light on the complex process that occurs in the development of human sperm stem cells.

5 Oct 2017

Researchers find genetic variation linked to effects of prenatal alcohol exposure

Researchers at the University of Helsinki, Finland, have found a genetic variation, which associates with the damage caused by maternal alcohol consumption. This genetic variation clarifies the role of genetic factors in the alcohol-induced developmental disorders and could be useful in future diagnostics.

5 Oct 2017

Study on cell stress response may hold promise for treating inflammation-related disorders

Stress – defined broadly – can have a profoundly deleterious effect on the human body. Even individual cells have their own way of dealing with environmental strains such as ultraviolet radiation from the sun or germs.

4 Oct 2017

Patented invention has potential to induce and regulate stem cell differentiation

An invention by Florida Institute of Technology’s Shengyuan Yang was found to naturally narrow the spreading of stem cells and has the potential to induce and regulate their differentiation.

4 Oct 2017

Scientists awarded $1.3 million grant to study relationship between traumatic brain injury and dementia

The U.S. Department of Defense has awarded a team of scientists and physicians from leading health care institutions across Phoenix a $1.3 million grant over three years to study traumatic brain injury and its relationship to dementia.

4 Oct 2017

TSRI scientists developed new strategy to discover novel anti-cancer therapies

Scientists at The Scripps Research Institute (TSRI) have developed and demonstrated a promising new strategy for the discovery of novel anti-cancer therapies.

30 Sep 2017

Columbia University receives $9.6 million NIH grant for ME/CFS research center

The National Institutes of Health has awarded a five-year $9.6 million grant to the Center for Infection and Immunity at Columbia University's Mailman School of Public Health to create the Center for Solutions for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (CfS for ME/CFS), an inter-disciplinary, inter-institutional research group dedicated to understanding the biology of the disease in order to develop effective means to diagnose, treat and prevent it.

27 Sep 2017

Adding, removing water from a stem cell can determine its role as bone or fat

Adding or removing water from a stem cell can change the destiny of the cell, researchers have discovered in a new study published in the Proceedings of the National Academy of Sciences.

27 Sep 2017

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

26 Sep 2017

Mother's diet during pregnancy could affect brain reward circuitry of children

Researchers in France found that rats who ate a junk food diet during pregnancy had heavier pups that strongly preferred the taste of fat straight after weaning. While a balanced diet in childhood seemed to reduce the pups' desire for fat, they nevertheless showed altered brain reward circuitry into adulthood.

25 Sep 2017

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

A major health problem in older people is age-associated osteoporosis -- the thinning of bone and the loss of bone density that increases the risk of fractures. Often this is accompanied by an increase in fat cells in the bone marrow.

22 Sep 2017

Researchers discover mechanism of drug resistance for ovarian and breast cancer cells

Researchers from the People's Friendship University of Russia have studied the mechanism of drug resistance for ovarian and breast cancer cells.

22 Sep 2017

Study may contribute to genetic understanding of high-altitude adaptation

Many research groups have recently explored human adaptation and successfully identified candidate genes to high altitude living among three major far-flung global populations: Tibetans, Ethiopians and Peruvians.

22 Sep 2017

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Inspired by the Labyrinth of Greek mythology, a new chip etched with fluid channels sends blood samples through a hydrodynamic maze to separate out rare circulating cancer cells into a relatively clean stream for analysis. It is already in use in a breast cancer clinical trial.

21 Sep 2017

Alcohol use may induce changes to cholesterol-regulating gene

In an analysis of the epigenomes of people and mice, researchers at Johns Hopkins Medicine and the National Institutes of Health report that drinking alcohol may induce changes to a cholesterol-regulating gene.

20 Sep 2017

Gene Expression News and Research

Further Reading

New computer program identifies different cell types based on gene expression patterns

Penn Medicine professor receives New Innovator Award from NIH

Researchers develop new diagnostic and prognosis method for early detection of liver cancer

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Researchers uncover promising targets for development of drugs against leishmaniasis

Study sheds light on complex process involved in development of sperm stem cells

Researchers find genetic variation linked to effects of prenatal alcohol exposure

Study on cell stress response may hold promise for treating inflammation-related disorders

Patented invention has potential to induce and regulate stem cell differentiation

Scientists awarded $1.3 million grant to study relationship between traumatic brain injury and dementia

TSRI scientists developed new strategy to discover novel anti-cancer therapies

Columbia University receives $9.6 million NIH grant for ME/CFS research center

Adding, removing water from a stem cell can determine its role as bone or fat

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Mother's diet during pregnancy could affect brain reward circuitry of children

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

Researchers discover mechanism of drug resistance for ovarian and breast cancer cells

Study may contribute to genetic understanding of high-altitude adaptation

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Alcohol use may induce changes to cholesterol-regulating gene

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