Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Study identifies cluster of dysregulated genes in pancreatic islets of type 2 diabetes patients

Type 2 diabetes, which affects >0.5 billion people worldwide, results from the inability of beta cells in the pancreatic islets to provide the body with enough insulin to maintain blood glucose levels within the range for a healthy life.

1 Dec 2017

Study provides insights on mechanisms involved in tolerance after kidney transplantation

A new study provides insights on the mechanisms that allow an individual's immune system to accept, rather than reject, a donor kidney. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, point to markers that could be monitored to assess and track the health of organs following transplantation.

1 Dec 2017

Study focuses on improving pharmacokinetic properties of therapeutic aptamers

Designing new therapeutic DNA aptamers with diverse side chains can improve their ability to interact with targets, and a new study describes characteristics of these side chains that may determine how long the aptamers remain in the bloodstream.

30 Nov 2017

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

Most complex diseases, such as obesity, longevity, and diabetes, are largely influenced by genetic factors. But at the same time, they are also modulated by environmental stimuli, such as diet and physical activity.

29 Nov 2017

Mental illness linked to early childhood adversity may be passed to next generation

Mental illness associated with early childhood adversity may be passed from generation to generation, according to a study of adults whose parents evacuated Finland as children during World War II.

29 Nov 2017

Specific gene expression patterns could be key to younger looking skin

Some individuals' skin appears more youthful than their chronologic age. Although many people try to achieve this with creams, lotions, injections, and surgeries, new research published in the Journal of the American Academy of Dermatology indicates that increased expression of certain genes may be the key to intrinsically younger looking - and younger behaving - skin.

29 Nov 2017

Research findings will help identify genetic causes of brain disorders

New findings will help to identify the genetic causes of brain disorders: researchers at the Universities of Basel, Bonn and Cologne have presented a systematic catalog of specific variable locations in the genome that influence gene activity in the human hippocampus, as they report in the journal Nature Communications.

27 Nov 2017

Distinct small differences in the human brain may contribute to our cognitive abilities

The most dramatic divergence between humans and other primates can be found in the brain, the primary organ that gives our species its identity.

23 Nov 2017

Metabolites significantly affected in chronic kidney disease, study finds

Chronic kidney disease (CKD) affects 1 in 7 people in the United States, according to the U.S. National Institute of Diabetes & Digestive & Kidney Diseases.

22 Nov 2017

Study finds specific tumor environment that stimulates cancer cells to metastasize

A new study, conducted by a team of researchers from the University of California, San Diego, has identified how the environment surrounding a tumor can stimulate metastatic behavior in the individual cancer cells. Researchers found that the tumor cells activate a particular set of genes and begin to form blood vessel-like structures when they are confined in a densely packed environment.

22 Nov 2017

Scientists discover how tumor environment can trigger metastatic behavior in cancer cells

A team of bioengineers and bioinformaticians at the University of California San Diego have discovered how the environment surrounding a tumor can trigger metastatic behavior in cancer cells.

22 Nov 2017

Analysis of aged brains reveals new details about Alzheimer's disease and dementia

In a comprehensive analysis of samples from 107 aged human brains, researchers at the Allen Institute for Brain Science, UW Medicine and Kaiser Permanente Washington Health Research Institute have discovered details that will help researchers better understand the biological bases for Alzheimer's disease and dementia in older populations.

21 Nov 2017

Researchers identify previously unknown breast cell types

A joint effort by breast cancer researchers and bioinformaticians has provided new insights into the molecular changes that drive breast development.

21 Nov 2017

$10 million gift creates new center at Northwestern University to study effects of environment on genes

A new $10 million gift from University trustees and supporters Louis A. Simpson '58 and Kimberly K. Querrey will create a center at Northwestern University Feinberg School of Medicine to study the effects of environment on the activation and expression of genes.

21 Nov 2017

Study identifies molecular pathway critical to development of fibrosis

A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis - scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.

15 Nov 2017

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate to all those different cell fates.

15 Nov 2017

Gene Expression News and Research

Further Reading

Study identifies cluster of dysregulated genes in pancreatic islets of type 2 diabetes patients

Study provides insights on mechanisms involved in tolerance after kidney transplantation

Study focuses on improving pharmacokinetic properties of therapeutic aptamers

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

Mental illness linked to early childhood adversity may be passed to next generation

Specific gene expression patterns could be key to younger looking skin

Research findings will help identify genetic causes of brain disorders

Distinct small differences in the human brain may contribute to our cognitive abilities

Metabolites significantly affected in chronic kidney disease, study finds

Study finds specific tumor environment that stimulates cancer cells to metastasize

Scientists discover how tumor environment can trigger metastatic behavior in cancer cells

Analysis of aged brains reveals new details about Alzheimer's disease and dementia

Researchers identify previously unknown breast cell types

$10 million gift creates new center at Northwestern University to study effects of environment on genes

Study identifies molecular pathway critical to development of fibrosis

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

Researchers use novel computational tool to understand complex disease processes

Researchers uncover link between abdominal aortic aneurysm and dysregulated tryptophan metabolism

Absence of VEGF-A in cancer-killing T cells accelerates tumor development

Epigenetic editing in healthy breast cells can set off chain reaction for tumor initiation

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