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Can barrier gestures be relaxed without causing a COVID-19 resurgence in France?

A new study focused on determining the magnitudes of a barrier gesture relaxation in France. Read more here.

1 Sep 2021

Studies outlines novel strategies for detecting cancer and minimal residual disease

The latest special issue of PLOS Medicine features five studies outlining novel strategies for detecting cancer and for identifying minimal residual disease - when a small number of tumor cells survive treatment, potentially leading to recurrence of cancer.

1 Sep 2021

A global genetic surveillance gap for SARS-CoV-2

Now a new study posted to the medRxiv* preprint server provides a perspective on the global disparities surrounding SARS-CoV-2 genomic surveillance, their causes and consequences, and possible solutions to maximize the impact of pathogen genome sequencing for efforts on public health.

1 Sep 2021

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of lung disease characterized by relentless scarring leading to death within an average of four years from the time of diagnosis.

31 Aug 2021

Breakthrough study could lead to much needed therapies for Huntington's disease

A new mechanism that stops the progression of Huntington's disease in cells has been identified by scientists at UCL and the University of Cambridge, as part of their research groups at the UK Dementia Research Institute.

31 Aug 2021

New study could help orthopedic surgeons to better identify patients for foot surgery

A new study by researchers at Hospital for Special Surgery in New York City could help orthopedic surgeons better identify which patients will benefit most from surgery to correct debilitating age-related deterioration of their foot arches.

31 Aug 2021

Study uses novel technology to map the brain circuitry of spirituality

Scientists have long suspected that religiosity and spirituality could be mapped to specific brain circuits, but the location of those circuits remains unknown. Now, a new study using novel technology and the human connectome, a map of neural connections, has identified a brain circuit that seems to mediate that aspect of our personality. The work appears in Biological Psychiatry, published by Elsevier.

31 Aug 2021

The tale of mRNA vaccines: Turning calamity into opportunity

In a review paper published in the journal Nature Reviews, researchers from Carnegie Mellon University and the University of Pennsylvania have described the underlying technologies for mRNA vaccines and their future prospects with improved delivery systems and applications in diseases beyond the ongoing COVID-19 pandemic.

31 Aug 2021

Moderate-vigorous physical activity found to be the most efficient at improving fitness

In the largest study performed to date to understand the relationship between habitual physical activity and physical fitness, researchers from Boston University School of Medicine (BUSM) have found that higher amount of time spent performing exercise (moderate-vigorous physical activity) and low-moderate level activity (steps) and less time spent sedentary, translated to greater physical fitness.

28 Aug 2021

Research analyzes the role of RNA tags in Alzheimer’s disease

Understanding the role of tau protein in Alzheimer's disease (AD) has led to new ways to diagnose it as well as the creation of medicines now in clinical trials to treat it.

28 Aug 2021

Researchers test remotely operated implantable drug delivery devices on the ISS

From Novartis to Lamborghini, Alessandro Grattoni and the Houston Methodist Research Institute have partnered with big names to leverage the International Space Station U.S. National Laboratory for space-based research and technology development with important benefits back on Earth.

28 Aug 2021

ACTG announces positive data for monoclonal antibody combination therapy from the ACTIV-2 study

The AIDS Clinical Trials Group, the largest global HIV research network, which has expanded its focus to include evaluating outpatient treatment for COVID-19, today announced positive data for the monoclonal antibody combination therapy BRII-196/BRII-198 from the ACTIV-2 study of Outpatient Monoclonal Antibodies and Other Therapies.

27 Aug 2021

Adding berzosertib to standard treatment for metastatic urothelial cancer does not extend patient survival

A Phase 2 trial led by City of Hope, a world-renowned research and treatment center for cancer and diabetes, suggests that adding the novel ataxia telangiectasia and Rad3-related (ATR) inhibitor drug berzosertib to standard-of-care chemotherapy for patients with metastatic urothelial cancer does not extend progression-free survival.

27 Aug 2021

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

Heart attacks and strokes are the main causes of death and loss of productive years globally. These clinical complications are caused by atherosclerosis, which is a chronic disease that leads to the accumulation of LDL cholesterol and immune cells in the inner layer of arteries and thereby resulting in the build-up of atherosclerotic plaques.

26 Aug 2021

Brain organoids provide a valuable model to study autism

Variations in the 16p11.2 region of the genome are associated with autism spectrum disorder. While people with genetic deletions in this region have larger heads (macrocephaly) and people with genetic duplications have smaller heads (microcephaly), both variation types affect brain development and function.

26 Aug 2021

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

In recent years, immune-based treatments for cancer have buoyed the hopes of doctors and patients alike. Drugs called immune checkpoint inhibitors have provided lifesaving benefits to a growing list of people with several types of cancer, including melanoma, lung cancer, bladder cancer, and many more.

25 Aug 2021

Researchers identify mechanism for formation of rare colorectal cancer subtype

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, recently discovered a mechanism to explain what drives the formation of mucinous colorectal adenocarcinoma (MAC), a rare subtype of colorectal cancer (CRC), and has also identified the genes responsible for the regulation of this mechanism.

25 Aug 2021

Therapeutics News and Research

Can barrier gestures be relaxed without causing a COVID-19 resurgence in France?

Studies outlines novel strategies for detecting cancer and minimal residual disease

A global genetic surveillance gap for SARS-CoV-2

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Breakthrough study could lead to much needed therapies for Huntington's disease

New study could help orthopedic surgeons to better identify patients for foot surgery

Study uses novel technology to map the brain circuitry of spirituality

The tale of mRNA vaccines: Turning calamity into opportunity

Moderate-vigorous physical activity found to be the most efficient at improving fitness

Research analyzes the role of RNA tags in Alzheimer’s disease

Researchers test remotely operated implantable drug delivery devices on the ISS

ACTG announces positive data for monoclonal antibody combination therapy from the ACTIV-2 study

Adding berzosertib to standard treatment for metastatic urothelial cancer does not extend patient survival

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

Brain organoids provide a valuable model to study autism

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

Researchers identify mechanism for formation of rare colorectal cancer subtype

Unconventional T cell and inflammation levels in COVID-19 during pregnancy

Microbiome startups promise to improve your gut health, but is the science solid?

Two studies on gastrointestinal stroma tumors describe advances that may lead to new treatments

Industry Focus eBook - Biotechnology (4th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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