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Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Liver cancer is the third leading cause of cancer death and the sixth most common cancer type worldwide.

12 Apr 2023

Radioimmunotherapy cures human non-Hodgkin lymphoma in animal model

A new nuclear medicine therapy can cure human non-Hodgkin lymphoma in an animal model, according to research published in the April issue of The Journal of Nuclear Medicine.

11 Apr 2023

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options.

11 Apr 2023

Dietary supplement N-acetylcysteine helps overcome treatment resistance in breast cancer

Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medication.

11 Apr 2023

How does e-cigarette vapor alter the gut microbiome, body weight, and systemic inflammation levels?

Researchers examine the effects of electronic cigarette (e-cigarette) vapor on gut microbiome, body weight, and systemic inflammation levels.

11 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Isolating tumor-reactive blood cells to treat cancers

Adoptive cell therapy (ACT) has become a promising immunotherapy tool to help treat advanced melanoma.

10 Apr 2023

Lack of therapeutic markers leads to poorer outcomes in triple negative breast cancer

A new review paper was published in Oncotarget's Volume 14 on March 31, 2023, entitled, "Crosstalk between triple negative breast cancer and microenvironment."

10 Apr 2023

Immunotherapy response in patients with advanced melanoma depends on prior treatments

Research led by scientists at UCLA Jonsson Comprehensive Cancer Center found that responses to a type of immunotherapy called PD-1 checkpoint blockade in patients with advanced melanoma depended on whether or not they had previously received another immunotherapy – CTLA-4 blockade – as well as other factors.

10 Apr 2023

Using the gene-editing tool to model certain liver tumor subtypes

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex.

10 Apr 2023

Immune checkpoint inhibitor treatment is facilitated by dietary tryptophan metabolite synthesized by Lactobacillus reuteri

Researchers highlight how dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment.

10 Apr 2023

Leveraging cell self-destruction to treat glioblastoma tumors

Glioblastoma is the most common type of brain tumor in adults. The disease is 100% fatal and there are no cures, making it the most aggressive type of cancer. Such a poor prognosis has motivated researchers and neurosurgeons to understand the biology of tumors with the goal of creating better therapies.

7 Apr 2023

What makes blackberries a superfood?

Researchers look at the phytochemical components of blackberries.

6 Apr 2023

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict — before treatment begins — how well patients with kidney cancer will respond to immunotherapy, according to new research directed by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

6 Apr 2023

Can metabolic phenotyping of pregnant women, beyond pre-pregnancy obesity or gestational diabetes status, improve the assessment of adiposity risk in offspring?

Researchers assessed whether metabolic phenotyping during pregnancy increases the risk of adiposity risk in the offspring.

6 Apr 2023

Tumor News and Research

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Radioimmunotherapy cures human non-Hodgkin lymphoma in animal model

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Dietary supplement N-acetylcysteine helps overcome treatment resistance in breast cancer

How does e-cigarette vapor alter the gut microbiome, body weight, and systemic inflammation levels?

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Isolating tumor-reactive blood cells to treat cancers

Lack of therapeutic markers leads to poorer outcomes in triple negative breast cancer

Immunotherapy response in patients with advanced melanoma depends on prior treatments

Using the gene-editing tool to model certain liver tumor subtypes

Immune checkpoint inhibitor treatment is facilitated by dietary tryptophan metabolite synthesized by Lactobacillus reuteri

Leveraging cell self-destruction to treat glioblastoma tumors

What makes blackberries a superfood?

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Can metabolic phenotyping of pregnant women, beyond pre-pregnancy obesity or gestational diabetes status, improve the assessment of adiposity risk in offspring?

Exploring the gut microbiome's role in rheumatoid arthritis pathogenesis

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Childhood cancer survivors maintaining a healthy lifestyle may have lower risk of mortality

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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