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Cellular maps capture COVID-19 pathogenesis in detail

Researchers in the United States and Finland have used tissues from people who died from coronavirus disease 2019 (COVID-19) to generate detailed cellular maps of the pathogenetic processes that occur within affected organs during severe disease.

1 Mar 2021

Study could offer a new way to treat Type 1 and Type 2 diabetes

Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team led by UT Southwestern reports in a new study.

1 Mar 2021

Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

A new study by researchers at Imperial College London, UK, discusses the effect of a vaccine dose, specifically the BNT162b2 candidate (also known as the ‘Pfizer-BioNTech’ vaccine), on neutralizing antibody titers in individuals who have already been infected with the virus.

1 Mar 2021

SARS-CoV-2 modulates host cell central carbon metabolism for reproduction

A team of scientists from Sweden and India has recently characterized the host cell metabolic alterations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Their findings reveal that SARS-CoV-2 modulates the host cell's central carbon metabolism to facilitate replication and infection propagation.

28 Feb 2021

Researchers review data related to high number of cancer deaths in China

The past century or so has seen unprecedented technological, scientific, and sociological evolution worldwide.

27 Feb 2021

Scientists develop a simple method to make drug precursor

Save your silver! It's better used for jewelry than as a catalyst for drugs. Rice University scientists have developed a greatly simplified method to make fluoroketones, precursors for drug design and manufacture that typically require a silver catalyst.

27 Feb 2021

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.

26 Feb 2021

New study aims to improve anti-cancer drug response predictions across cancer types

The goal of "precision oncology" is to be able to tailor treatments to each individual patient based on their cancer's unique molecular fingerprints.

26 Feb 2021

Researchers identify cells responsible for maintenance and regeneration of liver

While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery.

26 Feb 2021

Current screening guidelines may not detect liver cancer soon enough in African Americans

Early detection could reduce the number of African Americans dying from liver cancer, but current screening guidelines may not find cancer soon enough in this community, according to a study published in Cancer in February.

25 Feb 2021

Study provides new insight into the genetics of coronary artery disease

According to a new study published in The American Journal of Human Genetics, more than one third of genetic variants that increase the risk of coronary artery disease regulate the expression of genes in the liver. These variants have an impact on the expression of genes regulating cholesterol metabolism, among other things.

25 Feb 2021

Insilico Medicine discovers novel preclinical candidate to address idiopathic pulmonary fibrosis

Insilico Medicine has demonstrated a breakthrough in Artificial Intelligence ("AI") and drug discovery -- linking together generative chemistry and biology for the first time -- to discover a novel preclinical candidate addressing idiopathic pulmonary fibrosis ("IPF") and be validated with multiple human cell and animal model experiments.

25 Feb 2021

Study shows reliability and robustness of injectable anti-obesity medication

A second study of the injectable anti-obesity medication, semaglutide, has confirmed the large weight losses reported in a study earlier this month, establishing the reliability and robustness of this new drug.

24 Feb 2021

A practical guide to critical parameters in acute care testing

The acute care testing handbook is a practical guide to critical parameters in acute care testing such as pO2, lactate and troponin.

From Radiometer Medical 24 Feb 2021

Study offers new insights into "Niemann-Pick type C disease"

In the journal Nature Communications, scientists of the German Center for Neurodegenerative Diseases (DZNE) report new findings on the mechanisms of "Niemann-Pick type C disease" (NPC).

24 Feb 2021

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma

Cancer cells acquire growth advantages over normal cells in myriad ways. Changes in cell programming allow these cells to grow in an uncontrolled fashion, thereby forming the cancer mass.

23 Feb 2021

WVU researchers set to identify SARS-CoV-2 variants, mitigate strain outbreaks

West Virginia University scientists knew it was coming. When health officials confirmed the first three cases of a COVID-19 variant in West Virginia late Friday (Feb. 19), they were not surprised.

22 Feb 2021

High fructose diets might prevent proper functioning of peoples' immune system

New research by Swansea scientists in collaboration with researchers at the University of Bristol and the Francis Crick Institute in London has indicated that consuming a diet high in sugar fructose might prevent the proper functioning of peoples' immune systems in ways that have, until now, largely been unknown.

22 Feb 2021

Researchers urge European policymakers to make adequate resources available to tackle pancreatic cancer

Researchers have called on European policymakers to make adequate resources available to tackle pancreatic cancer, a disease that is almost invariably fatal and where little progress has been made over the past 40 years.

21 Feb 2021

Researchers seek to develop new cell culture technique to replace animal testing

While many studies take place in a petri glass in toxicology research, for some processes there is still a need for animal components such as serum or liver cell tissue.

20 Feb 2021

Liver News and Research

Cellular maps capture COVID-19 pathogenesis in detail

Study could offer a new way to treat Type 1 and Type 2 diabetes

Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

SARS-CoV-2 modulates host cell central carbon metabolism for reproduction

Researchers review data related to high number of cancer deaths in China

Scientists develop a simple method to make drug precursor

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

New study aims to improve anti-cancer drug response predictions across cancer types

Researchers identify cells responsible for maintenance and regeneration of liver

Current screening guidelines may not detect liver cancer soon enough in African Americans

Study provides new insight into the genetics of coronary artery disease

Insilico Medicine discovers novel preclinical candidate to address idiopathic pulmonary fibrosis

Study shows reliability and robustness of injectable anti-obesity medication

A practical guide to critical parameters in acute care testing

Study offers new insights into "Niemann-Pick type C disease"

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma

WVU researchers set to identify SARS-CoV-2 variants, mitigate strain outbreaks

High fructose diets might prevent proper functioning of peoples' immune system

Researchers urge European policymakers to make adequate resources available to tackle pancreatic cancer

Researchers seek to develop new cell culture technique to replace animal testing

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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