Genetic Engineering News and Research

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Low-carb potato will help win back die-hard carbohydrate counters

Potatoes may be on the no-no list for high-protein diets, but a University of Florida researcher says a new low-carb potato will help win back die-hard carbohydrate counters.

9 Jun 2004

Closed door session on genetically modified (GM) foods

Three officials who will judge on the controversial transatlantic trade dispute on genetically modified (GM) foods will today (Wednesday 2nd June) begin to take evidence behind closed doors.

2 Jun 2004

Novel molecular targeting technologies to deliver gene-silencing therapy

Researchers have combined novel molecular targeting technologies to deliver gene-silencing therapy specifically to tumor cells shielded by a normally impermeable obstacle, the blood brain barrier.

1 Jun 2004

Engineered virus could be ideal for targeting cancers with lethal gene therapy

Scientists from Cancer Research UK have taken advantage of the selfish behaviour of cancer cells to target them with a genetically engineered virus.

1 Jun 2004

Trial shows Daclizumab therapy improves multiple sclerosis outcome

A small clinical trial of patients with multiple sclerosis (MS) who did not respond to interferon alone found that adding the human antibody daclizumab improved patient outcome. Patients who received the combined therapy had a 78 percent reduction in new brain lesions and a 70 percent reduction in total lesions, along with other significant clinical improvements.

24 May 2004

Scientists have genetically engineered a mouse with extraordinary resistance to bowel cancer

Scientists have genetically engineered a mouse with extraordinary resistance to bowel cancer, delegates at the Cancer Research UK senior researchers' conference in Harrogate will hear today.

24 May 2004

Using gene therapy to fight rheumatoid arthritis

Guided by a similar principle, arthritis researchers at the University of Florida and Harvard University hope to use gene therapy to help joint cells pump out a harmless protein that parks in receptor sites, leaving a notorious inflammatory agent “circling the lot” and unable to cause pain, swelling and possible joint damage.

21 May 2004

Scientists have taken the first steps towards producing a sustainable and pure source of the healthy fats found in oily fish

Eating such fish is encouraged as part of a healthy diet as their oils are rich in very long chain polyunsaturated fatty acids (VLCPUFAs). However, views on the health-promoting nature of VLCPUFAs have to be balanced against the marine pollution that can cause fish, and the oils extracted from them, to be contaminated with heavy metals and dioxins, and the fact that fish stocks are in global decline.

20 May 2004

Launch of Crucial Genetics, a state-of-the-art genetic profiling service

The University of Glasgow has linked up with venture capital company Fifty-Six Ltd. to launch Crucial Genetics, a state-of-the-art genetic profiling service. The company is based within customised laboratory facilities at the Southern General Hospital, Glasgow and is equipped with the latest automated fluorescent DNA laser scanning machinery.

19 May 2004

Genetically engineered viruses may create new class of cancer therapies

A genetically engineered virus can selectively kill cancerous cells in the lung and colon while leaving healthy cells intact, according to new research published today in Cancer Research by William Wold and colleagues at Saint Louis University School of Medicine.

15 May 2004

Cancer-causing gene identified that may play a key role in the development of leukemia and other cancers

Using genetically engineered mice, researchers at the Johns Hopkins Children's Center have identified a gene that functions as a cancer-causing gene (or oncogene) and may play a key role in the development of leukemia and other cancers in children and adults.

15 May 2004

Strategy to treat obesity through molecular liposuction

Researchers at The University of Texas M. D. Anderson Cancer Center have designed a strategy to treat obesity through “molecular liposuction.” The therapy destroys blood vessels supporting fat accumulation — causing the fat to rapidly break down and disappear.

10 May 2004

$FDA approves INFUSE® bone graft which improves fracture healing$

FDA approves INFUSE® bone graft which improves fracture healing

Medtronic, Inc. has announced that the U.S. Food and Drug Administration (FDA) approved the use of INFUSE® Bone Graft in the treatment of acute, open fractures of the tibial shaft, a long bone in the lower leg. The approval broadens the indications for INFUSE Bone Graft, a product that has been used since 2002 in spinal surgery with metallic cages to treat tens of thousands of patients.

4 May 2004

New technique to deliver gene therapy to soft-tissue tumors

Using new research and technology that shows bone marrow-derived mesenchymal stem cells (MSCs) will engraft at the site of a tumor and contribute to the growth of stromal fibroblasts (the healthy tissue surrounding a tumor)

2 May 2004

How flexing of blood vessels during a heartbeat might contribute to heart disease

Duke biomedical engineers have received more than $2.2 million from the National Institutes of Health (NIH) to continue their explorations of how the complex moving and flexing of blood vessels during a heartbeat might contribute to heart disease.

28 Apr 2004

Results look promising in Alzheimer’s gene therapy trial

Surgical placement of genetically modified tissue directly into the brains of patients with Alzheimer’s disease, an experimental approach to delaying brain cell loss associated with the disease, leads to increased metabolic activity in the brain, with cells apparently responding to the insertion of growth factor-producing grafts

28 Apr 2004

Discovery shows how single genetic mutation can cause complex disorders

Bardet-Biedl syndrome (BBS), characterized by obesity, learning disabilities and eye and kidney problems, is caused by genetic mutations in the BBS family of genes. Now, researchers who've long studied the condition have discovered that genetic mutations in one of those genes, called BBS4, lead to cell death by disrupting the cells' internal "highway" system.

25 Apr 2004

Genetically engineered bugs to fight cancer

GENETICALLY engineered bacteria could become the latest weapons against cancer, Cancer Research UK scientists suggest in a study published today 22nd April 2004.

22 Apr 2004

Link between iron regulation and the immune system

Patients with chronic inflammatory disorders, including infections, inflammatory bowel disease, arthritis and cancer, commonly become anemic. The anemia can make them sicker, is sometimes severe enough to require a blood transfusion, and responds only partially to current treatments.

20 Apr 2004

Genetic trick makes gene therapy vectors more versatile

A genetic trick used by viruses to replicate themselves has been adapted for laboratory use to build complex protein structures required by immune system cells, according to investigators at St. Jude Children’s Research Hospital.

7 Apr 2004