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Exciting cost-effective SARS-CoV-2 vaccine candidate using Newcastle disease

Experts warn that the world may see repeated waves of the COVID-19 pandemic. However, scientists around the world are working hard to create a protective vaccine or antiviral, which could help to reduce the number of deaths and cases the next time around.

29 Jul 2020

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Analyses of lung fluid cells from COVID-19 patients conducted on the nation's fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body's response to SARS-CoV-2.

28 Jul 2020

A new cell-based gene therapy approach to better treat patients with hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

28 Jul 2020

Moderna coronavirus vaccine candidate moves to phase 3 with 30,000 participants

The world’s most significant coronavirus disease (COVID-19) vaccine study is underway in the United States, with a planned 30,000 volunteers. The phase 3 clinical trial aims to examine the efficacy and safety of the candidate vaccine developed by the National Institutes of Health and Moderna Inc.

28 Jul 2020

Curi Bio Acquires Dana Solutions

Curi Bio has acquired Dana Solutions, a pioneer in the application of artificial intelligence and machine learning to in vitro cell-based assays.

From Curi Bio 27 Jul 2020

National clinical trial to test potential vaccine against SARS-CoV-2

UC San Diego Health and the Altman Clinical and Translational Research Institute, part of UC San Diego School of Medicine, will be sites for an accelerated national clinical trial to assess the efficacy and immunogenicity of a vaccine intended to protect against SARS-CoV-2, the novel coronavirus that causes COVID-19.

25 Jul 2020

New study helps identify patients at higher risk of statin-related myopathy

Statins are prescribed to millions of people worldwide to reduce their risks of suffering heart attacks and strokes.

25 Jul 2020

Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

An experimental messenger RNA (mRNA)-based vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits protective immune responses in mice and non-human primates, researchers report on July 23rd in the journal Cell.

24 Jul 2020

Study investigates the causes and effects of excessive exercise in people with eating disorders

For most people, exercise is healthy for both body and mind. Hours spent jogging, bike riding or lifting weights can elevate mood, boost heart health, build muscle and spur weight loss.

24 Jul 2020

Hypertension drugs are associated with elevated incidence of heart failure

L-type calcium channel blockers (LCCBs) -- the most widely used drugs for treating hypertension -- may harm the heart as much as help it, according to a new study.

24 Jul 2020

Century-old mercury pollution is persistent in Connecticut's Still River

Western Connecticut is known for rolling hills, rich history, and industry, such as hat making. Once called the "Hat City of the World," Danbury thrived.

23 Jul 2020

Gene in fat cells plays a key role in regulating insulin sensitivity

Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows.

23 Jul 2020

New strategy allows long-term, non-invasive tracking of cardiomyocytes

A new platform reported on today in STEM CELLS Translational Medicine (SCTM) will enable long-term tracking of cardiomyocytes produced from induced pluripotent stem cells (iPSCs) after implantation into the heart.

23 Jul 2020

Genetic testing can help make well-informed decisions about heart health

Genetic testing and counseling for inherited cardiovascular diseases may help patients and their families make well-informed decisions about managing their heart health, according to "Genetic Testing for Inherited Cardiovascular Diseases," a new scientific statement from the American Heart Association, published today in the Association's journal Circulation: Genomic and Precision Medicine.

23 Jul 2020

C-Path gets positive response from FDA for drug-induced skeletal muscle injury safety biomarkers

Critical Path Institute announced today that the Biomarker Qualification Program at the Center for Drug Evaluation and Research in the U.S. Food and Drug Administration issued a positive response to the Letter of Intent developed by C-Path's Predictive Safety Testing Consortium and Duchenne Regulatory Science Consortium, for a panel of four safety biomarkers of acute drug-induced skeletal muscle injury.

23 Jul 2020

Vesigen Therapeutics to develop and commercialize novel drug-delivery technologies

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Erectile dysfunction drugs lower the accumulation of toxic proteins in zebrafish models

The aberrant buildup of misfolded proteins is a hallmark of a host of disorders, including neurodegenerative diseases such as Alzheimer's and Parkinson's.

22 Jul 2020

Scientific evidence shows GLDH is a safe biomarker for drug-induced liver injury

Critical Path Institute (C-Path) announced today that the Biomarker Qualification Program (BQP) at the Center for Drug Evaluation and Research (CDER) from the U.S. Food and Drug Administration (FDA) issued a positive response to the Qualification Plan (QP) for glutamate dehydrogenase (GLDH) as a safety biomarker for drug-induced liver injury (DILI), developed by C-Path's Predictive Safety Testing Consortium (PSTC) and Duchenne Regulatory Science Consortium (D-RSC).

22 Jul 2020

Cutting-edge surgery enables patients with facial paralysis to close their eyes

Surgeons at UT Southwestern have developed and analyzed the benefits of a cutting-edge technique that provides patients with facial paralysis the ability to close their eyes.

21 Jul 2020

Autopsies reveal unexpected changes in the hearts of COVID-19 patients

A series of autopsies conducted by LSU Health New Orleans pathologists shows the damage to the hearts of COVID-19 patients is not the expected typical inflammation of the heart muscle associated with myocarditis, but rather a unique pattern of cell death in scattered individual heart muscle cells.

21 Jul 2020

Muscle News and Research

Exciting cost-effective SARS-CoV-2 vaccine candidate using Newcastle disease

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

A new cell-based gene therapy approach to better treat patients with hemophilia A

Moderna coronavirus vaccine candidate moves to phase 3 with 30,000 participants

Curi Bio Acquires Dana Solutions

National clinical trial to test potential vaccine against SARS-CoV-2

New study helps identify patients at higher risk of statin-related myopathy

Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

Study investigates the causes and effects of excessive exercise in people with eating disorders

Hypertension drugs are associated with elevated incidence of heart failure

Century-old mercury pollution is persistent in Connecticut's Still River

Gene in fat cells plays a key role in regulating insulin sensitivity

New strategy allows long-term, non-invasive tracking of cardiomyocytes

Genetic testing can help make well-informed decisions about heart health

C-Path gets positive response from FDA for drug-induced skeletal muscle injury safety biomarkers

Vesigen Therapeutics to develop and commercialize novel drug-delivery technologies

Erectile dysfunction drugs lower the accumulation of toxic proteins in zebrafish models

Scientific evidence shows GLDH is a safe biomarker for drug-induced liver injury

Cutting-edge surgery enables patients with facial paralysis to close their eyes

Autopsies reveal unexpected changes in the hearts of COVID-19 patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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