Pathogen News and Research

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Too much of c-FLIPR protein can trigger autoimmune diseases

So-called c-FLIP proteins inhibit signaling cascades that can lead to apoptosis. This is important temporarily in the response to pathogens to ensure that lymphocytes, a type of immune cells, can proliferate sufficiently.

11 Apr 2014

Novel study uncovers way coughs and sneezes stay airborne for long distances

The next time you feel a sneeze coming on, raise your elbow to cover up that multiphase turbulent buoyant cloud you're about to expel.

9 Apr 2014

Humans appear to develop immunity against strain-specific Lyme disease that lasts for years

Lyme disease, if not treated promptly with antibiotics, can become a lingering problem for those infected. But a new study led by researchers from the University of Pennsylvania has some brighter news: Once infected with a particular strain of the disease-causing bacteria, humans appear to develop immunity against that strain that can last six to nine years.

3 Apr 2014

UM researchers awarded FDA contract to expand high-throughput sequencing database

Researchers at the Institute for Genome Sciences at the University of Maryland School of Medicine have been awarded a research program contract from the U.S. Food and Drug Administration (FDA) to sequence, assemble, and annotate a population of bacterial pathogens using two high-throughput sequencing (HTS) technologies in support of the expansion of a vetted public reference database.

2 Apr 2014

Novel proteins may lead to new ways to combat venereal disease

Researchers at Oregon State University have discovered novel proteins in, or on the surface of the bacteria that causes gonorrhea, which offer a promising new avenue of attack against a venereal disease that is showing increased resistance to the antibiotics used to treat it.

1 Apr 2014

S. pneumoniae is commonest cause of paediatric CAP

Streptococcus pneumoniae is the predominant cause of community-acquired pneumonia among children in Belgium, with non-vaccine serotypes accounting for the majority of cases, a Belgian study shows.

31 Mar 2014

Experimental vaccine for HSV-2 infection reduces rate of viral shedding at 6 months

Updated Phase 1/2a results with GEN-003, a vaccine candidate under development by Genocea Biosciences, Inc. (Nasdaq: GNCA) for the treatment of herpes simplex virus type 2 (HSV-2) infection, showed the experimental vaccine to generate highly significant reductions in both the number of clinical lesion days and rate of viral shedding at six months after the final vaccine dose.

27 Mar 2014

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

Infectious disease specialists at the Johns Hopkins Children's Center have identified a protein that regulates the body's immune response to cytomegalovirus (CMV), a common pathogen that causes lifelong infections and can lead to devastating illness in newborns and those with weakened immune systems.

27 Mar 2014

Emergence of community-acquired infections due to ESBL-producing bacteria on the rise

The emergence of community-acquired infections, such as urinary tract infections (UTI), due to strains resistant to common antibiotics are on the rise, according to Rhode Island Hospital researchers. The study is published online in the journal Antimicrobial Resistance and Infection Control.

26 Mar 2014

Scientist receives $275,000 grant to study human papillomavirus that causes head and neck cancer

Basic scientists focus on understanding how things work, so most don't get the chance to directly impact other people's lives. That's why Michelle Ozbun, PhD, is very excited about her recent grant to study human papillomavirus.

25 Mar 2014

Study examines events that lead to sepsis by Streptococcus pneumoniae

An international team of academics, including Professor Marco Oggioni from the University of Leicester's Department of Genetics, has studied how localised infections can turn into the dangerous systematic disease sepsis - and has identified for the first time through genetic evidence that a single bacteria could be the cause.

24 Mar 2014

Researchers find immune receptor for uric acid crystals

The surface of immune system cells is home to a number of receptors which are able to detect pathogens. As soon as these receptors are activated, inflammation occurs and the body's defense mechanisms kick in. Immune cells also have receptors that regulate or even suppress immunological responses to prevent damage to individual cells.

21 Mar 2014

Scientist receives $147,157 grant from NIH to find cure for infectious disease

A Clemson University scientist was awarded a two-year, $147,157 grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to find a cure for an infectious disease.

20 Mar 2014

Many community hospitals prescribe ineffective antibiotics for patients with bloodstream infections

Growing drug resistance, a high prevalence of S. aureus bacteria and ineffective antibiotics prescribed to one in three patients are among the challenges facing community hospitals in treating patients with serious bloodstream infections, according to researchers at Duke Medicine.

19 Mar 2014

Pathogen News and Research

Too much of c-FLIPR protein can trigger autoimmune diseases

Novel study uncovers way coughs and sneezes stay airborne for long distances

Humans appear to develop immunity against strain-specific Lyme disease that lasts for years

UM researchers awarded FDA contract to expand high-throughput sequencing database

Novel proteins may lead to new ways to combat venereal disease

S. pneumoniae is commonest cause of paediatric CAP

Experimental vaccine for HSV-2 infection reduces rate of viral shedding at 6 months

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

Emergence of community-acquired infections due to ESBL-producing bacteria on the rise

Scientist receives $275,000 grant to study human papillomavirus that causes head and neck cancer

Study examines events that lead to sepsis by Streptococcus pneumoniae

Researchers find immune receptor for uric acid crystals

Scientist receives $147,157 grant from NIH to find cure for infectious disease

Many community hospitals prescribe ineffective antibiotics for patients with bloodstream infections

New research raises hopes of new class of drugs to combat antibiotic resistant infections

Gut bacteria and blood cell development relationship helps immune system fight infection

Parasites in human are most likely to interact via food source

UNIGE discovers new class of molecules toxic for Plasmodium pathogen

Sleep apnoea may be risk factor for pneumonia

Researchers examine association between diabetes and obesity

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