Immune System News and Research

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Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Immune checkpoint inhibitor (ICI) therapy is a type of treatment for melanoma, the deadliest form of skin cancer, which blocks proteins on tumor or immune cells that prevent the immune system from killing cancer cells.

19 Sep 2022

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

If a secretion in the lungs’ alveoli is not cleared regularly, breathing difficulties can develop. In a study published in Science Immunology, a team led by Alexander Mildner and Achim Leutz has now explained the pivotal role of the transcription factor C/EBPb in this process.

16 Sep 2022

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19's viral pathogenesis - a theory that was posited two years ago by a team of researchers at the Department of Energy's Oak Ridge National Laboratory.

16 Sep 2022

Mortality risk higher among children with primary immunodeficiency diseases infected with SARS-CoV-2

Children with certain immunodeficiency diseases carry mutations in genes that regulate the body's immune system against viral infections and they have a higher mortality rate due to COVID-19.

16 Sep 2022

Itchy eczema in children finally gets relief

This is the first large-scale, randomized, placebo-controlled trial of a monoclonal antibody in any skin disease, including eczema, in children as young as six months. The study, which included 31 sites in Europe and North America, was published in The Lancet.

16 Sep 2022

Higher levels of microbiota engraftment linked to greater chances of transplantation success

From incurable intestinal infections to metabolic syndrome, from melanoma, to chronic inflammatory bowel disease, such as irritable bowel syndrome, to Tourette's syndrome: many diseases can potentially be cured by Fecal Microbiota Transplantation (FMT), and researchers from the Catholic University, Rome and the University of Trento have shown that the greater the level of engraftment of the transplanted microorganisms, the greater the chances of success of the therapy.

15 Sep 2022

Moral values determine COVID vaccination acceptance rates in the United States

Even though COVID-19 vaccines are safe, effective and widely available in the United States, many Americans are still hesitant to get vaccinated.

15 Sep 2022

New mechanism may prevent the natural aging of immune cells

A new mechanism that slows down and may even prevent the natural aging of immune cells – one of the nine 'hallmarks of aging' – has been identified by an international team led by UCL scientists.

15 Sep 2022

Disruption of actin cytoskeleton is key to triggering human immune response, research finds

Researchers from Cleveland Clinic's Florida Research and Innovation Center (FRIC) found that disruption of a cellular structure, known as the actin cytoskeleton, is a "priming signal" for the body to respond to a virus.

15 Sep 2022

New immunotherapy approach may lead to an effective treatment for fibrosis

Chronic diseases often lead to fibrosis, a condition in which organ tissue suffers from excessive scarring.

15 Sep 2022

COVID-19 vaccine safety concerns result in lower vaccination rates among pregnant individuals in the United States

In a new study, researchers evaluated the factors associated with lower coronavirus disease 2019 (COVID-19) vaccination rates among pregnant individuals in the United States (U.S.).

15 Sep 2022

What is the COVID-19 prevalence among neonates?

A new study evaluated the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in newborns.

15 Sep 2022

Development of improved monoclonal antibodies against SARS-CoV-2

In a new study, researchers explored strategies for the development of effective monoclonal antibodies (mAbs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2022

Extra caution needed while screening depressed teenagers with Type 1 diabetes

The scoring results of widely used depression-screening tools should be carefully adjusted to better detect the condition in teenagers with Type 1 diabetes mellitus (T1D), according to a new study published in the American Diabetes Association journal Diabetes Care.

14 Sep 2022

Immune System News and Research

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

Mortality risk higher among children with primary immunodeficiency diseases infected with SARS-CoV-2

Itchy eczema in children finally gets relief

Higher levels of microbiota engraftment linked to greater chances of transplantation success

Moral values determine COVID vaccination acceptance rates in the United States

New mechanism may prevent the natural aging of immune cells

Disruption of actin cytoskeleton is key to triggering human immune response, research finds

New immunotherapy approach may lead to an effective treatment for fibrosis

COVID-19 vaccine safety concerns result in lower vaccination rates among pregnant individuals in the United States

What is the COVID-19 prevalence among neonates?

Development of improved monoclonal antibodies against SARS-CoV-2

Extra caution needed while screening depressed teenagers with Type 1 diabetes

Exploring successional infectious disease ecology among human pathogens

New drug marks cancer cells for destruction by the immune system

Gut commensal bacteria promote the development of virus-induced cancer by suppressing the immune system

Study shows vaccine-derived poliovirus in infant with severe immunodeficiency

How effective is vitamin D supplementation in COVID-19?

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